{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T02:19:45Z","timestamp":1791944385761,"version":"4.3.4"},"reference-count":9,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,5,15]],"date-time":"2024-05-15T00:00:00Z","timestamp":1715731200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:p>Anti interleukin (IL)-17A therapy is a common and effective treatment for psoriasis, but there are also risks of infection. In this case, we presented a patient who experienced a swift progression of condyloma acuminatum on the genitals during psoriasis treatment with secukinumab, a human IL-17A antagonist. Through this case, we strongly suspect that anti IL-17A treatment may promote the onset and rapid progression of low-risk HPV-associated condyloma acuminatum.<\/jats:p>","DOI":"10.3389\/fmed.2024.1387620","type":"journal-article","created":{"date-parts":[[2024,5,15]],"date-time":"2024-05-15T05:08:52Z","timestamp":1715749732000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":4,"title":["Rapid progression of condyloma acuminatum caused by IL-17A antibody treatment: a case report"],"prefix":"10.3389","volume":"11","author":[{"given":"Fang","family":"Sun","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenze","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2024,5,15]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"1301","DOI":"10.1016\/S0140-6736(20)32549-6","article-title":"Psoriasis","volume":"397","author":"Griffiths","year":"2021","journal-title":"Psoriasis Lancet"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"107925","DOI":"10.1016\/j.pharmthera.2021.107925","article-title":"Secukinumab for the treatment of psoriasis, psoriatic arthritis, and axial spondyloarthritis: physical and pharmacological properties underlie the observed clinical efficacy and safety","volume":"229","author":"Kolbinger","year":"2022","journal-title":"Pharmacol Ther"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"1945","DOI":"10.1001\/jama.2020.4006","article-title":"Pathophysiology, clinical presentation, and treatment of psoriasis: a review","volume":"323","author":"Armstrong","year":"2020","journal-title":"JAMA"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1111\/ajd.14227","article-title":"Adult genital psoriasis: An updated review for clinicians","author":"Wu","year":"2024","journal-title":"Australas J Dermatol"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1111\/ajd.13865","article-title":"The impact of systemic psoriasis treatments on human papillomavirus activation and propagation","volume":"63","author":"Korecka","year":"2022","journal-title":"Australas J Dermatol"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"786","DOI":"10.1093\/ije\/dyaa027","article-title":"Human papillomavirus infection associated with increased risk of new-onset psoriasis: a nationwide population-based cohort study","volume":"49","author":"Chen","year":"2020","journal-title":"Int J Epidemiol"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"e15735","DOI":"10.1111\/dth.15735","article-title":"Prevalence of genital and oral human papillomavirus infection among psoriasis patients on biologic therapy","volume":"35","author":"Rob","year":"2022","journal-title":"Dermatol Ther"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"1179","DOI":"10.1111\/bjd.16799","article-title":"Impact of anti-interleukin-17 treatment on cutaneous and genital human papillomavirus infection","volume":"179","author":"Brunet-Possenti","year":"2018","journal-title":"Br J Dermatol"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"e256","DOI":"10.1111\/ijd.14910","article-title":"Spontaneous resolution of human papillomavirus infection in a patient with psoriasis given secukinumab","volume":"59","author":"Ayhan","year":"2020","journal-title":"Int J Dermatol"}],"container-title":["Frontiers in Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2024.1387620\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,15]],"date-time":"2024-05-15T05:08:53Z","timestamp":1715749733000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2024.1387620\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,15]]},"references-count":9,"alternative-id":["10.3389\/fmed.2024.1387620"],"URL":"https:\/\/doi.org\/10.3389\/fmed.2024.1387620","relation":{},"ISSN":["2296-858X"],"issn-type":[{"value":"2296-858X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,15]]},"article-number":"1387620"}}