{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T16:00:27Z","timestamp":1753891227610,"version":"3.41.2"},"reference-count":31,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,6,12]],"date-time":"2024-06-12T00:00:00Z","timestamp":1718150400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:p>Rosai-Dorfman disease (RDD) is an uncommon histiocytic disorder that occurs in nodal and\/or extranodal sites. Extranodal RDD exhibits a wide range of clinical and radiological presentations, frequently leading to misdiagnoses. Involvement of the gastrointestinal (GI) system is uncommon, accounting for less than 1% of the reported cases. Here we present a case of a 54-year-old male who complained of abdominal distention and was diagnosed with RDD affecting the sigmoid colon, manifesting as a sigmoid mass. The patient had a past medical history of liver transplantation due to hepatocellular carcinoma (HC). This report details the multiphase contrast-enhanced computed tomography (CT) and fluorodeoxyglucose (<jats:sup>18<\/jats:sup>F-FDG) positron emission tomography (PET-CT) imaging findings of RDD involving the sigmoid colon without lymphadenopathy, and a review of the relevant literature is provided.<\/jats:p>","DOI":"10.3389\/fmed.2024.1425112","type":"journal-article","created":{"date-parts":[[2024,6,12]],"date-time":"2024-06-12T04:23:31Z","timestamp":1718166211000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Case report: A rare case of isolated sigmoid Rosai-Dorfman disease on contrast-enhanced CT and 18F-FDG PET\/CT"],"prefix":"10.3389","volume":"11","author":[{"given":"Wanling","family":"Qi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhehuang","family":"Luo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mingyan","family":"Shao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fengxiang","family":"Liao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linfeng","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2024,6,12]]},"reference":[{"key":"ref1","first-page":"1169","article-title":"Ad\u00e9nites avec surcharge lipidique, de l'enfant ou de l'adulte jeune, observ\u00e9es aux Antilles et au Mali. (Quatre observations) [Adenitis with lipid excess, in children or young adults, seen in the Antilles and in Mali. (4 cases)]","volume":"58","author":"Destombes","year":"1965","journal-title":"Bull Soc Pathol Exot Filiales"},{"key":"ref2","first-page":"63","article-title":"Sinus histiocytosis with massive lymphadenopathy. 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(sinus histiocytosis with massive lymphadenopathy): review of 11 cases","volume":"31","author":"Lauwers","year":"2000","journal-title":"Hum Pathol"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1093\/ajcp\/aqad047","article-title":"How I diagnose Rosai-Dorfman disease","volume":"160","author":"Ravindran","year":"2023","journal-title":"Am J Clin Pathol"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"2877","DOI":"10.1182\/blood-2018-03-839753","article-title":"Consensus recommendations for the diagnosis and clinical management of Rosai-Dorfman-Destombes disease","volume":"131","author":"Abla","year":"2018","journal-title":"Blood"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1111\/j.1365-2141.1995.tb05313.x","article-title":"Evidence for a polyclonal nature of the cell infiltrate in sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease)","volume":"91","author":"Paulli","year":"1995","journal-title":"Br 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