{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T00:15:20Z","timestamp":1777076120088,"version":"3.51.4"},"reference-count":50,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,11,28]],"date-time":"2024-11-28T00:00:00Z","timestamp":1732752000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Capsule endoscopy (CE) is widely used for intestinal examination; however, capsule aspiration into the airway is a serious complication that requires urgent intervention. We present a management case report and review 39 cases from 2003 to 2023, providing insights into the prevention and treatment of capsule aspiration.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case presentation<\/jats:title><jats:p>A 69-year-old man with chronic bronchitis and emphysema presented with 7\u202fmonths of intermittent melena. After swallowing a capsule endoscope (PillCam<jats:sup>\u2122<\/jats:sup> SB 3), he had a brief cough and chest tightness. Imaging confirmed aspiration in the right intermediate bronchus, and non-invasive removal procedures were unsuccessful.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Real-time imaging confirmed the lodged capsule. Non-invasive methods, such as coughing and chest percussion, were unsuccessful. Therefore, flexible bronchoscopy was performed under general anesthesia to retrieve the capsule using a snare, which was then placed into the duodenum using a gastroscope.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The capsule was successfully retrieved, and the patient recovered well, completing the endoscopy without further issues.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our case study and literature review highlight the need for careful attention to high-risk groups in CE, including the elderly and individuals with neurological or swallowing difficulties. A thorough history review and real-time monitoring are essential for preventing complications. Bronchoscopy is preferred for CE retrieval due to its advantages. Manufacturers are urged to improve CE safety, with respiratory physicians helping internists in managing this potentially life-threatening complication.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fmed.2024.1442245","type":"journal-article","created":{"date-parts":[[2024,11,28]],"date-time":"2024-11-28T04:20:06Z","timestamp":1732767606000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Capsule endoscopy aspiration and respiratory physician\u2019s treatment insights: a case report and literature review"],"prefix":"10.3389","volume":"11","author":[{"given":"Yinxue","family":"Zhou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongmei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min","family":"Zhuang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hua","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lijie","family":"Qi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lingyun","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiaxing","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2024,11,28]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1016\/j.gie.2005.05.002","article-title":"Complications, limitations, and failures of capsule endoscopy: a review of 733 cases","volume":"62","author":"Rondonotti","year":"2005","journal-title":"Gastrointest Endosc"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"784","DOI":"10.1016\/j.gie.2020.12.001","article-title":"Video capsule endoscopy","volume":"93","author":"Melson","year":"2021","journal-title":"Gastrointest Endosc"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1111\/jgh.16379","article-title":"Long-term outcomes of patients with obscure gastrointestinal bleeding after negative capsule endoscopy","volume":"39","author":"Hirata","year":"2023","journal-title":"J Gastroenterol Hepatol"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"399","DOI":"10.5662\/wjm.v13.i5.399","article-title":"Crohn\u2019s disease and clinical management today: how it does?","volume":"13","author":"da Silva J\u00fanior","year":"2023","journal-title":"World J Methodol"},{"key":"ref5","first-page":"58","article-title":"Diagnostic and therapeutic approach to small bowel disorders through capsule endoscopy and double-balloon endoscopy","volume":"37","author":"De Simone","year":"2017","journal-title":"Revista de gastroenterologia del Peru"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"644","DOI":"10.3390\/jpm12040644","article-title":"Computer-aided diagnosis of gastrointestinal protruded lesions using wireless capsule endoscopy: a systematic review and diagnostic test accuracy meta-analysis","volume":"12","author":"Kim","year":"2022","journal-title":"J Pers Med"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"428","DOI":"10.1097\/MEG.0000000000000821","article-title":"Short article: aspiration of capsule endoscopes: a comprehensive review of the existing literature","volume":"29","author":"Yung","year":"2017","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"2758","DOI":"10.1007\/s10620-011-1666-2","article-title":"Tracheal aspiration of a capsule endoscope: a new case report and literature compilation of an increasingly reported complication","volume":"56","author":"Lucendo","year":"2011","journal-title":"Dig Dis Sci"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"b3420","DOI":"10.1136\/bmj.b3420","article-title":"Capsule endoscopy","volume":"339","author":"Moglia","year":"2009","journal-title":"BMJ"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"200","DOI":"10.3949\/ccjm.89a.20061","article-title":"Capsule endoscopy in gastrointestinal disease: evaluation, diagnosis, and treatment","volume":"89","author":"Akpunonu","year":"2022","journal-title":"Cleve Clin J Med"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"1157","DOI":"10.1016\/j.gie.2016.12.024","article-title":"Retention associated with video capsule endoscopy: systematic review and meta-analysis","volume":"85","author":"Rezapour","year":"2017","journal-title":"Gastrointest Endosc"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1055\/s-2003-41527","article-title":"Aspiration of an M2A capsule","volume":"35","author":"Schneider","year":"2003","journal-title":"Endoscopy"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"220","DOI":"10.11604\/pamj.2014.19.220.4952","article-title":"Tracheobronchial foreign bodies in adults","volume":"19","author":"Benjelloun","year":"2014","journal-title":"Pan Afr Med J"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"604","DOI":"10.7326\/0003-4819-112-8-604","article-title":"Tracheobronchial foreign bodies in adults","volume":"112","author":"Limper","year":"1990","journal-title":"Ann Intern Med"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"e0269493","DOI":"10.1371\/journal.pone.0269493","article-title":"Foreign-body aspiration into the lower airways in adults; multicenter study","volume":"17","author":"Jang","year":"2022","journal-title":"PLoS One"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"1168","DOI":"10.1016\/j.amjsurg.2022.05.032","article-title":"Foreign body aspirations in children and adults","volume":"224","author":"Ulas","year":"2022","journal-title":"Am J Surg"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"746","DOI":"10.1055\/s-2004-825685","article-title":"Endoscopy-assisted capsule endoscopy in patients with swallowing disorders","volume":"36","author":"Toth","year":"2004","journal-title":"Endoscopy"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1097\/MEG.0b013e328326cae2","article-title":"Unintentional video capsule bronchoscopy","volume":"21","author":"Bredenoord","year":"2009","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"472","DOI":"10.1136\/gut.2003.033845","article-title":"Mild respiratory distress after wireless capsule endoscopy","volume":"53","author":"Buchkremer","year":"2004","journal-title":"Gut"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"926","DOI":"10.1016\/S0016-5107(04)00291-3","article-title":"Aspiration of a capsule endoscope","volume":"59","author":"Sinn","year":"2004","journal-title":"Gastrointest Endosc"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"845","DOI":"10.1016\/S0016-5107(04)02032-2","article-title":"Asymptomatic aspiration of a capsule endoscope","volume":"60","author":"Tabib","year":"2004","journal-title":"Gastrointest Endosc"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"E343","DOI":"10.1055\/s-2007-995327","article-title":"Aspiration - an important complication of small-bowel video capsule endoscopy","volume":"39","author":"Nathan","year":"2007","journal-title":"Endoscopy"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1016\/j.otohns.2007.09.011","article-title":"Aspiration of a capsule endoscope and description of a unique retrieval technique","volume":"137","author":"Sepehr","year":"2007","journal-title":"Otolaryngology"},{"key":"ref24","first-page":"215","article-title":"Pulmonary aspiration of a capsule endoscope","volume":"102","author":"Shiff","year":"2007","journal-title":"Am J Gastroenterol"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"568","DOI":"10.1510\/icvts.2008.190058","article-title":"Asymptomatic bronchial aspiration of a video capsule","volume":"8","author":"Guy","year":"2009","journal-title":"Interact Cardiovasc Thorac Surg"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"1602","DOI":"10.1038\/ajg.2009.93","article-title":"Aspiration of video capsule: rare but potentially life-threatening complication to include in your consent form","volume":"104","author":"Koulaouzidis","year":"2009","journal-title":"Am J Gastroenterol"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1016\/j.gie.2008.09.044","article-title":"Asymptomatic bronchial aspiration and retention of a capsule endoscope","volume":"69","author":"Leeds","year":"2009","journal-title":"Gastrointest Endosc"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"114","DOI":"10.5009\/gnl.2010.4.1.114","article-title":"A case of asymptomatic aspiration of a capsule endoscope with a successful resolution","volume":"4","author":"Choi","year":"2010","journal-title":"Gut Liver"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1159\/000255763","article-title":"Capsule endoscopy removal through flexible bronchoscopy","volume":"79","author":"Depriest","year":"2010","journal-title":"Respiration"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"e37","DOI":"10.1016\/j.cgh.2009.10.024","article-title":"Electronic image of the month. Small bowel video capsule aspiration with bronchoscopic-assisted extraction","volume":"8","author":"Kurtz","year":"2010","journal-title":"Clin Gastroenterol Hepatol"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1186\/1752-1947-5-341","article-title":"Asymptomatic bronchial aspiration and prolonged retention of a capsule endoscope: a case report","volume":"5","author":"Pezzoli","year":"2011","journal-title":"J Med Case Rep"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1097\/LBR.0b013e31826e3b53","article-title":"Aspiration of capsule endoscope and successful bronchoscopic extraction","volume":"19","author":"Girdhar","year":"2012","journal-title":"J Bronchol Interven Pulmonol"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"1727","DOI":"10.1007\/s10620-012-2173-9","article-title":"Tracheal aspiration of a capsule endoscope: not always a benign event","volume":"57","author":"Parker","year":"2012","journal-title":"Dig Dis Sci"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"761","DOI":"10.1111\/jgh.12173","article-title":"Education and imaging. Gastrointestinal: symptomatic bronchial aspiration of capsule endoscope - a significant complication","volume":"28","author":"Ding","year":"2013","journal-title":"J Gastroenterol Hepatol"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"E185","DOI":"10.1177\/000313481307900503","article-title":"Video endoscope removal from the right main bronchus using a flexible esophagogastroduodenoscope","volume":"79","author":"Hall","year":"2013","journal-title":"Am Surg"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"438","DOI":"10.4321\/S1130-01082013000700015","article-title":"Aspiration of capsule endoscope","volume":"105","author":"Pereira","year":"2013","journal-title":"Rev Esp Enferm Dig"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1016\/j.rgmx.2013.04.003","article-title":"Capsule endoscope aspiration: a common complication?","volume":"78","author":"S\u00e1nchez-Ch\u00e1vez","year":"2013","journal-title":"Revista de gastroenterologia de Mexico"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"69","DOI":"10.14309\/crj.2014.2","article-title":"Unexpected capsule endoscopy images reveal aspiration","volume":"1","author":"Hussan","year":"2014","journal-title":"ACG Case Rep J"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"E6","DOI":"10.1055\/s-0034-1377543","article-title":"Late presentation of capsule endoscope aspiration with successful extraction by flexible bronchoscopy utilizing a snare wire loop","volume":"47","author":"Amarna","year":"2015","journal-title":"Endoscopy"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1016\/j.jpge.2015.03.004","article-title":"Aspiration of capsule endoscopy","volume":"22","author":"Magalh\u00e3es-Costa","year":"2015","journal-title":"GE Port J Gastroenterol"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1159\/000441382","article-title":"Capsule endoscope aspiration after repeated attempts for ingesting a patency capsule","volume":"9","author":"Mannami","year":"2015","journal-title":"Case Rep Gastroenterol"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"605","DOI":"10.17235\/reed.2016.4363\/2016","article-title":"Asymptomatic bronchial aspiration of capsule endoscope: a significant complication","volume":"108","author":"Juanmarti\u00f1ena Fern\u00e1ndez","year":"2016","journal-title":"Rev Esp Enferm Dig"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1159\/000453587","article-title":"Bronchial aspiration of capsule endoscope","volume":"93","author":"Buscot","year":"2017","journal-title":"Respiration"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"e 1556","DOI":"10.7759\/cureus.1556","article-title":"Bravo\u00ae capsule aspiration: a rare case report","volume":"9","author":"Haseeb","year":"2017","journal-title":"Cureus"},{"key":"ref45","first-page":"441","article-title":"Transient tracheo-bronquial aspiration of capsule endoscope","volume":"80","author":"Juanmarti\u00f1ena Fern\u00e1ndez","year":"2017","journal-title":"Acta Gastro-Enterol Belg"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"878","DOI":"10.17235\/reed.2017.5244\/2017","article-title":"Real time visualization may be advisable to exclude aspiration in patients undergoing capsule endoscopy examination","volume":"109","author":"Ribaldone","year":"2017","journal-title":"Rev Esp Enferm Dig"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1016\/j.rgmx.2018.01.002","article-title":"Ten-hour asymptomatic bronchoaspiration of a capsule endoscopy camera","volume":"83","author":"Keil-R\u00edos","year":"2018","journal-title":"Revista de gastroenterologia de Mexico"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"e24138","DOI":"10.7759\/cureus.24138","article-title":"Necessity of swallow evaluations in the elderly prior to capsule endoscopy","volume":"14","author":"Gaisinskaya","year":"2022","journal-title":"Cureus"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"rjac385","DOI":"10.1093\/jscr\/rjac385","article-title":"Capsule endoscopy in airway: a difficult extraction","volume":"2022","author":"Tamang","year":"2022","journal-title":"J Surg Case Rep"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"e12242","DOI":"10.1002\/anr3.12242","article-title":"Tubeless field anaesthesia for surgical removal of an aspirated endoscopy capsule","volume":"11","author":"Grounds","year":"2023","journal-title":"Anaesthesia Rep"}],"container-title":["Frontiers in Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2024.1442245\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,28]],"date-time":"2024-11-28T04:20:10Z","timestamp":1732767610000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2024.1442245\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,28]]},"references-count":50,"alternative-id":["10.3389\/fmed.2024.1442245"],"URL":"https:\/\/doi.org\/10.3389\/fmed.2024.1442245","relation":{},"ISSN":["2296-858X"],"issn-type":[{"value":"2296-858X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,28]]},"article-number":"1442245"}}