{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,19]],"date-time":"2026-07-19T17:38:50Z","timestamp":1784482730314,"version":"3.55.0"},"reference-count":19,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,12,4]],"date-time":"2024-12-04T00:00:00Z","timestamp":1733270400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:p>Negative pressure pulmonary edema (NPPE) is a form of non-cardiogenic pulmonary edema triggered by a swift increase in negative intrapleural pressure due to upper airway obstruction and represents a potential cause of acute respiratory failure. This study documents a case of NPPE post-endotracheal extubation subsequent to general anesthesia. The patient, a young female, underwent a \u201claparoscopy-assisted unilateral salpingectomy\u201d under general anesthesia for an ectopic pregnancy. Immediately post-extubation, the patient exhibited a sudden decline in oxygen saturation and tachypnea. Pink frothy secretions were suctioned from the oral and nasal cavities. Swift interventions, including oxygen therapy, non-invasive ventilation, diuretics, and corticosteroids, were administered. The patient\u2019s condition was effectively managed, and after 6\u202fdays of treatment, she was discharged from the hospital following full recovery.<\/jats:p>","DOI":"10.3389\/fmed.2024.1467541","type":"journal-article","created":{"date-parts":[[2024,12,4]],"date-time":"2024-12-04T04:26:01Z","timestamp":1733286361000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":5,"title":["Negative pressure pulmonary edema: a case report and literature 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