{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T11:32:34Z","timestamp":1774611154668,"version":"3.50.1"},"reference-count":24,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,1,27]],"date-time":"2025-01-27T00:00:00Z","timestamp":1737936000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>Nausea and vomiting in pregnancy (NVP) affect approximately 70\u201385% of pregnant women, starting between weeks 6 and 8 and often subsiding by week 20. This study evaluates the therapeutic approaches of Italian gynecologists in the treatment of NVP. In the Italian healthcare system, gynecologists play a central role in prenatal care and are the primary healthcare providers for pregnant women, unlike in other countries where midwives may have a more prominent role.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>From June to September 2022, a survey of Italian gynecologists was conducted during 15 scientific conferences. The questionnaire collected demographic data and information on clinical practices to support the management of NVP. Statistical analysis assessed the effect of demographic characteristics on clinical behavior.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Data from 157 participants, mainly women (72.61%) and professionals from the Public Health System (63.69%), were analyzed. 77.71% always checked NVP during the first visit, based on patients\u2019 reports (84.71%). 54.78% prescribed medication in mild cases, mainly the doxylamine\/pyridoxine combination (64.97%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>The results show varied practices influenced by demographic and professional factors. Many physicians treat only severe cases of NVP, perceiving it as a transient discomfort, which may lead to poor management. Balanced care is needed to improve the quality of life for pregnant women with NVP.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fmed.2025.1462860","type":"journal-article","created":{"date-parts":[[2025,1,27]],"date-time":"2025-01-27T11:26:52Z","timestamp":1737977212000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Assessing the approaches to nausea and vomiting in pregnancy: insights from a nationwide survey of Italian gynecologists (PURITY light)"],"prefix":"10.3389","volume":"12","author":[{"given":"Romolo","family":"Di Iorio","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paola","family":"Bianchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Casolati","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Piccolo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario","family":"Mangrella","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2025,1,27]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-024-06376-4","article-title":"Genome-wide association study of nausea and vomiting during pregnancy in Japan: The TMM BirThree cohort study.","volume":"24","author":"Yonezawa","year":"2024","journal-title":"BMC Pregnancy Childbirth."},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.3390\/nu15040933","article-title":"Nausea and vomiting during early pregnancy among Chinese women and its association with nutritional intakes.","volume":"15","author":"Zhu","year":"2023","journal-title":"Nutrients."},{"key":"B3","doi-asserted-by":"publisher","first-page":"30","DOI":"10.5468\/ogs.2018.61.1.30","article-title":"Evaluation of nausea and vomiting in pregnancy using the pregnancy-unique quantification of emesis and nausea scale in Korea.","volume":"61","author":"Choi","year":"2018","journal-title":"Obstet Gynecol Sci."},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-017-1249-0","article-title":"The burden of nausea and vomiting during pregnancy: Severe impacts on quality of life, daily life functioning and willingness to become pregnant again - results from a cross-sectional study.","volume":"17","author":"Heitmann","year":"2017","journal-title":"BMC Pregnancy Childbirth."},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2021-058364","article-title":"Usability of pregnancy-unique quantification of emesis questionnaire in women hospitalised for hyperemesis gravidarum: A prospective cohort study.","volume":"12","author":"Laitinen","year":"2022","journal-title":"BMJ Open."},{"key":"B6","doi-asserted-by":"publisher","first-page":"1553","DOI":"10.3390\/healthcare9111553","article-title":"The pregnancy-unique quantification of emesis and nausea (Puqe-24): Configural, measurement, and structural invariance between nulliparas and multiparas and across two measurement time points.","volume":"9","author":"Hada","year":"2021","journal-title":"Healthcare (Switzerland)."},{"key":"B7","first-page":"965","article-title":"Nausea and vomiting of pregnancy.","volume":"89","author":"Herrell","year":"2014","journal-title":"Am. 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