{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T16:00:46Z","timestamp":1753891246882,"version":"3.41.2"},"reference-count":33,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,3,19]],"date-time":"2025-03-19T00:00:00Z","timestamp":1742342400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:p>A trichobezoar is an intraluminal mass of hair growing continuously with additional ingestion, while Rapunzel syndrome refers to a giant gastric trichobezoar that extends from the stomach into the small intestine. We present a case of Rapunzel syndrome as an uncommon cause of upper gastrointestinal (GI) symptoms in a young adult woman who denied trichotillomania and trichophagia. Preoperative radiological assessment was pivotal in planning a preferable therapeutic approach. The patient underwent laparotomy and prepyloric gastrotomy, resulting in satisfactory postoperative outcomes. Trichobezoars are extremely rare and predominantly affect young women with underlying psychiatric conditions. Although uncommon, they cause severe upper gastrointestinal symptoms and may even lead to various complications. This case report helps in understanding the presentation of gastric trichobezoar and Rapunzel syndrome, including their range of symptoms, radiological appearance, and associated findings, to make an accurate diagnosis and guide an appropriate treatment approach.<\/jats:p>","DOI":"10.3389\/fmed.2025.1504822","type":"journal-article","created":{"date-parts":[[2025,3,19]],"date-time":"2025-03-19T07:08:29Z","timestamp":1742368109000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Case Report on Rapunzel syndrome: a large gastric trichobezoar extending to the proximal jejunum in a young adult female"],"prefix":"10.3389","volume":"12","author":[{"given":"Ksenija","family":"Mijovi\u0107","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dragan","family":"Vasin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanela","family":"Hasanagi\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jelica","family":"Vukmirovi\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tijana","family":"Tomi\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vasko","family":"To\u0161i\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aleksandar","family":"Pavlovi\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dragan","family":"Ma\u0161ulovi\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aleksandra","family":"\u0110uri\u0107 Stefanovi\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2025,3,19]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"54","DOI":"10.4240\/wjgs.v3.i4.54","article-title":"Trichobezoar: a rare cause of bowel obstruction","volume":"3","author":"Gaujoux","year":"2011","journal-title":"World J Gastrointest Surg"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"31","DOI":"10.5334\/jbsr.2478","article-title":"Trichobezoar","volume":"105","author":"De Melio","year":"2021","journal-title":"J Belg Soc Radiol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"330","DOI":"10.5114\/pg.2013.38738","article-title":"The giant in the stomach - trichobezoar","volume":"8","author":"Kazanowski","year":"2013","journal-title":"Prz Gastroenterol"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"TD01","DOI":"10.7860\/JCDR\/2017\/28593.10594","article-title":"Rapunzel Syndrome","volume":"11","author":"Lalith","year":"2017","journal-title":"J Clin Diagn Res"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"2504","DOI":"10.1016\/j.jpedsurg.2020.04.020","article-title":"Gastrointestinal trichobezoar: an experience with 17 cases","volume":"55","author":"Mirza","year":"2020","journal-title":"J Pediatr Surg"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"20180080","DOI":"10.1259\/bjrcr.20180080","article-title":"Large gastric trichobezoar causing failure to thrive and iron deficiency anaemia in an adolescent girl: a case report emphasising the imaging findings and review of the literature","volume":"5","author":"Lyons","year":"2019","journal-title":"BJR Case Rep"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1016\/j.ajp.2016.07.008","article-title":"Trichobezoar (Rapunzel syndrome) in an adolescent patient with trichotillomania and generalized anxiety disorder: a case report","volume":"23","author":"Kumar Bn","year":"2016","journal-title":"Asian J Psychiatr"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"136963","DOI":"10.1155\/2012\/136963","article-title":"Gastric trichobezoar: an enduring intrigue","volume":"2012","author":"Mewa Kinoo","year":"2012","journal-title":"Case Rep Gastrointest Med"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1186\/1752-1947-8-79","article-title":"Unusual trichobezoar of the stomach and the intestine: a case report","volume":"8","author":"Al-Janabi","year":"2014","journal-title":"J Med Case Rep"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"99","DOI":"10.3121\/cmr.2009.822","article-title":"Rapunzel syndrome: a comprehensive review of an unusual case of trichobezoar","volume":"7","author":"Gonuguntla","year":"2009","journal-title":"Clin Med Res"},{"key":"ref11","first-page":"339","article-title":"The Rapunzel syndrome. 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