{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T16:02:08Z","timestamp":1753891328882,"version":"3.41.2"},"reference-count":14,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,3,5]],"date-time":"2025-03-05T00:00:00Z","timestamp":1741132800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:p>Afferent loop obstruction (ALO) induced by gallstone ileus after pancreaticoduodenectomy (PD) is rare. We present a case of ALO after the Whipple procedure in a 62-year-old male with a rare cause of gallstone ileus. He was admitted to the hospital with epigastric pain, fever, and jaundice two years after experiencing intermittent abdominal pain. With the help of computed tomography (CT) and magnetic resonance cholangiopancreatography (MRCP) gallstone ileus was confirmed and the patient underwent emergency surgery. Intraoperative findings indicated that internal herniation, adhesions and a stuck intra-pancreatic duct catheter caused gallstone formation and eventually led to ALO. The patient underwent prompt surgical intervention and ultimately recovered well. This case report holds a significant potential to contribute to the focus on the details of the Whipple procedure to prevent ALO and gallstone ileus.<\/jats:p>","DOI":"10.3389\/fmed.2025.1522046","type":"journal-article","created":{"date-parts":[[2025,3,5]],"date-time":"2025-03-05T07:10:48Z","timestamp":1741158648000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Afferent loop obstruction induced by gallstone ileus after Whipple procedure: a case report and literature review"],"prefix":"10.3389","volume":"12","author":[{"given":"Danfeng","family":"Shen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haibin","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peng","family":"Chang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiang","family":"Gu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongxing","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2025,3,5]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1002\/jhbp.656","article-title":"Comparative analysis of afferent loop obstruction between laparoscopic and open approach in pancreaticoduodenectomy","volume":"26","author":"Song","year":"2019","journal-title":"J Hepatobiliary Pancreat Sci"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"1841","DOI":"10.1080\/08941939.2022.2113188","article-title":"Developments in the diagnosis and Management of Cholecystoenteric Fistula","volume":"35","author":"Liu","year":"2022","journal-title":"J Investig Surg"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"8866254","DOI":"10.1155\/2020\/8866254","article-title":"Gallstone ileus decades after cholecystectomy and pylorus-preserving Whipples","volume":"2020","author":"Mugino","year":"2020","journal-title":"Case Rep Surg"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"106177","DOI":"10.1016\/j.ijscr.2021.106177","article-title":"Bezoar as a cause of jejunal afferent loop mass after pylorus preserving pancreaticoduodedectomy: a case report","volume":"85","author":"Lee","year":"2021","journal-title":"Int J Surg Case Rep"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"E176","DOI":"10.1055\/a-1046-1845","article-title":"Endoscopic electrohydraulic lithotripsy of an enterolith causing afferent loop syndrome after Whipple\u2019s operation","volume":"52","author":"Lim","year":"2020","journal-title":"Endoscopy"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"1136","DOI":"10.1097\/JS9.0000000000000373","article-title":"The SCARE 2023 guideline: updating consensus surgical CAse REport (SCARE) guidelines","volume":"109","author":"Sohrabi","year":"2023","journal-title":"Int J Surg"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"892","DOI":"10.3238\/arztebl.m2021.0096","article-title":"Gallstone ileus without Pneumobilia","volume":"118","author":"Miller","year":"2021","journal-title":"Dtsch Arztebl Int"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"5018","DOI":"10.1016\/j.radcr.2024.07.166","article-title":"What are the clues to gallstone ileus when stones don\u2019t show up on scans? 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