{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T20:56:12Z","timestamp":1782334572624,"version":"3.54.5"},"reference-count":41,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,7,21]],"date-time":"2025-07-21T00:00:00Z","timestamp":1753056000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:sec><jats:title>Objective or purpose<\/jats:title><jats:p>To detect the short-term impact of cataract surgery on retinal layers thickness, as the exact mechanism of fundus changes after phacoemulsification has not yet been fully clarified.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>A retrospective observational study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects, participants, and\/or controls<\/jats:title><jats:p>Seventy eyes of 70 patients with age ranging from 49 to 92 years, scheduled for cataract surgery, were included.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods, intervention, or testing<\/jats:title><jats:p>All subjects underwent a complete ophthalmological examination, including ART-OCT volume with Heidelberg Spectralis before and approximately one month later cataract surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>The macula was divided into a central foveal region and four parafoveal regions (superior, inferior, nasal, temporal). The scans were then automatically segmented into the different retinal layers and the changes in each layer were assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The results revealed that both the inner retinal layers and the entire retina exhibited a statistically significant thickening in foveal and parafoveal region: IRL (<jats:italic>p<\/jats:italic> &amp;lt; 0.001), ONL (<jats:italic>p<\/jats:italic> &amp;lt; 0.001), GCL (<jats:italic>p<\/jats:italic> = 0.010), RNFL (<jats:italic>p<\/jats:italic> = 0.020), and ALL (<jats:italic>p<\/jats:italic> &amp;lt; 0.001). Conversely, the outer retinal layers showed a statistically significant reduction in thickness only within the parafoveal regions: ORL (<jats:italic>p<\/jats:italic> &amp;lt; 0.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study may provide a pathophysiological explanation for post-phacoemulsification changes affecting the retina.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fmed.2025.1537402","type":"journal-article","created":{"date-parts":[[2025,7,21]],"date-time":"2025-07-21T05:23:04Z","timestamp":1753075384000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["The short term impact of uncomplicated cataract surgery on retinal layers thickness"],"prefix":"10.3389","volume":"12","author":[{"given":"Marco","family":"Gioia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maddalena","family":"De 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