{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T14:39:20Z","timestamp":1754145560951,"version":"3.41.2"},"reference-count":49,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T00:00:00Z","timestamp":1752710400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Digestive system autotransplantation is an emerging surgical technique used to treat complex digestive diseases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This study conducted a bibliometric analysis of 748 publications from the Web of Science Core Collection (WoSCC) database, using VOSviewer and CiteSpace tools to map research trends, author contributions, and institutional collaborations. Articles were selected based on their relevance to digestive system autotransplantation, focusing on autologous liver, pancreatic, and small intestine transplantation. The analysis included publication volume, citation counts, key authors, leading journals, and keyword co-occurrence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The analysis revealed a steady rise in publications between 2004 and 2015, followed by a gradual decline after 2016. The United States leads in research output, accounting for 40.11% of publications, followed by China. The leading institutions are predominantly based in the United States, with the University of Minnesota System producing the most publications. High-frequency keywords include autologous transplantation, pancreatic transplantation, chronic pancreatitis (CP), and postoperative complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Digestive system autotransplantation is a promising approach for complex cases. Continued interdisciplinary collaboration and focus on clinical outcomes will drive future advancements.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fmed.2025.1537446","type":"journal-article","created":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T05:25:41Z","timestamp":1752729941000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Advancements and trends in digestive system autotransplantation: a bibliometric and visualization analysis"],"prefix":"10.3389","volume":"12","author":[{"given":"Aimitaji","family":"Abulaiti","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Talaiti","family":"Tuergan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alimu","family":"Tulahong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruiqing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yingmei","family":"Shao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tuerganaili","family":"Aji","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2025,7,17]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1097\/SLA.0000000000001059","article-title":"Total pancreatectomy with islet autotransplantation: summary of an NIDDK workshop","volume":"261","author":"Bellin","year":"2015","journal-title":"Ann Surg."},{"key":"B2","first-page":"1002","volume-title":"J Hepatol.","author":"Hwang","year":"2018"},{"key":"B3","doi-asserted-by":"publisher","first-page":"1976","DOI":"10.1111\/ajt.12812","article-title":"The current state of intestine transplantation: indications, techniques, outcomes and challenges","volume":"14","author":"Sudan","year":"2014","journal-title":"Am J Transplant"},{"key":"B4","doi-asserted-by":"publisher","first-page":"873","DOI":"10.3390\/cancers11060873","article-title":"Multidisciplinary management of patients with unresectable hepatocellular carcinoma: a critical appraisal of current evidence","volume":"11","author":"Gholam","year":"2019","journal-title":"Cancers"},{"key":"B5","doi-asserted-by":"publisher","first-page":"766","DOI":"10.1097\/SLA.0000000000004270","volume":"272","author":"Kato","year":"2020","journal-title":"Ann Surg."},{"key":"B6","doi-asserted-by":"publisher","first-page":"106126","DOI":"10.1016\/j.ijsu.2021.106126","article-title":"Unresectable GIST liver metastases and liver transplantation: a review and theoretical basis for a new indication","volume":"94","author":"Fern\u00e1ndez","year":"2021","journal-title":"Inte J Surg."},{"key":"B7","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1038\/nrgastro.2014.216","article-title":"The concept of gut rehabilitation and the future of visceral transplantation","volume":"12","author":"Abu-Elmagd","year":"2015","journal-title":"Nat Rev Gastroenterol Hepatol."},{"key":"B8","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1016\/j.suc.2017.09.012","volume":"98","author":"Liou","year":"2018","journal-title":"Surg Clin North Am."},{"key":"B9","first-page":"117","volume-title":"Hepatobiliary Pancreat Dis Int.","author":"Yang","year":"2024"},{"key":"B10","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1093\/gastro\/gox027","article-title":"Intestinal autotransplantation","volume":"5","author":"Wu","year":"2017","journal-title":"Gastroenterol Rep."},{"key":"B11","doi-asserted-by":"publisher","first-page":"1037","DOI":"10.1016\/j.jhep.2018.07.006","volume":"69","author":"Aji","year":"2018","journal-title":"J Hepatol."},{"key":"B12","doi-asserted-by":"publisher","first-page":"e230808","DOI":"10.1136\/bcr-2019-230808","volume":"12","author":"George","year":"2019","journal-title":"BMJ Case Rep"},{"key":"B13","doi-asserted-by":"publisher","first-page":"640","DOI":"10.4269\/ajtmh.23-0276","article-title":"Case report: semi-ex vivo hepatectomy combined with autologous liver transplantation for alveolar echinococcosis in children","volume":"109","author":"Xia","year":"2023","journal-title":"Am J Trop Med Hyg."},{"key":"B14","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1016\/j.ijid.2018.11.016","volume":"79","author":"Shen","year":"2019","journal-title":"Int J Infect Dis."},{"key":"B15","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1093\/bjs\/znaa112","article-title":"Parenchyma-sparing vessel-guided major hepatectomy: nonsense or new paradigm in liver surgery?","volume":"108","author":"Torzilli","year":"2021","journal-title":"Br J Surg."},{"key":"B16","doi-asserted-by":"publisher","first-page":"2217","DOI":"10.1007\/s00423-021-02310-w","article-title":"Vascular surgery in liver resection","volume":"406","author":"Radulova-Mauersberger","year":"2021","journal-title":"Langenbeck Arch Surg."},{"key":"B17","doi-asserted-by":"publisher","first-page":"1964","DOI":"10.1007\/s11605-018-4022-4","article-title":"Remnant liver-to-standard liver volume ratio below 40% is safe in ex vivo liver resection and autotransplantation","volume":"23","author":"Shen","year":"2019","journal-title":"J Gastrointest Surg."},{"key":"B18","doi-asserted-by":"publisher","first-page":"20240926","DOI":"10.1515\/med-2024-0926","article-title":"Autologous liver transplantation for unresectable hepatobiliary malignancies in enhanced recovery after surgery model","volume":"19","author":"Liu","year":"2024","journal-title":"Open Med."},{"key":"B19","doi-asserted-by":"publisher","first-page":"1668","DOI":"10.1111\/ajt.14621","article-title":"Novel techniques and preliminary results of ex vivo liver resection and autotransplantation for end-stage hepatic alveolar echinococcosis: a study of 31 cases","volume":"18","author":"Yang","year":"2018","journal-title":"Am J Transplant."},{"key":"B20","doi-asserted-by":"publisher","first-page":"2663","DOI":"10.4240\/wjgs.v15.i11.2663","article-title":"Systematic sequential therapy for ex vivo liver resection and autotransplantation: a case report and review of literature","volume":"15","author":"Hu","year":"2023","journal-title":"World J Gastrointest Surg."},{"key":"B21","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1001\/jamasurg.2014.932","article-title":"Autologous islet transplantation with remote islet isolation after pancreas resection for chronic pancreatitis","volume":"150","author":"Tai","year":"2015","journal-title":"JAMA Surg."},{"key":"B22","doi-asserted-by":"publisher","first-page":"761","DOI":"10.3390\/cancers15030761","article-title":"Pancreatic cancer in chronic pancreatitis: pathogenesis and diagnostic approach","volume":"15","author":"Le Cosquer","year":"2023","journal-title":"Cancers"},{"key":"B23","doi-asserted-by":"publisher","first-page":"1034","DOI":"10.1016\/j.hpb.2019.10.2440","article-title":"Diabetes development after distal pancreatectomy: results of a 10 year series","volume":"22","author":"Tariq","year":"2020","journal-title":"HPB."},{"key":"B24","doi-asserted-by":"publisher","first-page":"435","DOI":"10.3949\/ccjm.83a.15056","article-title":"Total pancreatectomy and islet cell autotransplantation: definitive treatment for chronic pancreatitis","volume":"83","author":"Arce","year":"2016","journal-title":"Cleve Clin J Med."},{"key":"B25","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1210\/er.2018-00154","article-title":"Pancreatic islet transplantation in humans: recent progress and future directions","volume":"40","author":"Rickels","year":"2019","journal-title":"Endocr Rev."},{"key":"B26","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1016\/j.surg.2019.12.001","article-title":"Gastrointestinal tract reconstruction in adults with ultra-short bowel syndrome: surgical and nutritional outcomes","volume":"168","author":"Cruz RJ","year":"2020","journal-title":"Surgery"},{"key":"B27","doi-asserted-by":"publisher","first-page":"462","DOI":"10.1097\/SLA.0000000000006178","article-title":"Intestinal autotransplantation for locally advanced or locally recurrent colon cancer invading SMA","volume":"281","author":"Wu","year":"2025","journal-title":"Ann Surg."},{"key":"B28","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1002\/bjs.1800810404","article-title":"Short bowel syndrome: metabolic and surgical management","volume":"81","author":"Shanbhogue","year":"1994","journal-title":"Br J Surg."},{"key":"B29","doi-asserted-by":"publisher","first-page":"S16","DOI":"10.1053\/j.gastro.2005.12.002","article-title":"Causes and management of intestinal failure in children","volume":"130","author":"Goulet","year":"2006","journal-title":"Gastroenterology"},{"key":"B30","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1016\/j.gtc.2018.01.011","article-title":"Adult intestinal transplantation","volume":"47","author":"Matsumoto","year":"2018","journal-title":"Gastroenterol Clin North Am."},{"key":"B31","doi-asserted-by":"publisher","first-page":"2388","DOI":"10.1056\/NEJMc0909351","article-title":"Intestinal transplantation","volume":"361","author":"Pironi","year":"2009","journal-title":"N Engl J Med"},{"key":"B32","doi-asserted-by":"publisher","first-page":"2177","DOI":"10.1007\/s00423-021-02093-0","article-title":"The technical aspects of ex vivo hepatectomy with autotransplantation: a systematic review and meta-analysis","volume":"406","author":"Baimas-George","year":"2021","journal-title":"Langenbeck Arch Surg."},{"key":"B33","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1016\/j.surg.2020.05.036","article-title":"Outcomes of ex vivo liver resection and autotransplantation: a systematic review and meta-analysis","volume":"168","author":"Zawistowski","year":"2020","journal-title":"Surgery."},{"key":"B34","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1111\/ctr.12695","article-title":"Current principles and practice in autologous intraportal islet transplantation: a meta-analysis of the technical considerations","volume":"30","author":"Kumar","year":"2016","journal-title":"Clin Transplant."},{"key":"B35","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1097\/MOT.0000000000000999","article-title":"From liver surgery to liver transplant surgery: new developments in autotransplantation","volume":"27","author":"Lu","year":"2022","journal-title":"Curr Opin Organ Transplant."},{"key":"B36","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1186\/s12951-023-02033-8","article-title":"Research trends on nanomaterials in gastric cancer: a bibliometric analysis from 2004 to 2023","volume":"21","author":"Ling","year":"2023","journal-title":"J Nanobiotechnology."},{"key":"B37","doi-asserted-by":"publisher","first-page":"4823","DOI":"10.7150\/jca.44126","article-title":"Research trends on the relationship between microbiota and gastric cancer: a bibliometric analysis from 2000 to 2019","volume":"11","author":"Zhang","year":"2020","journal-title":"J Cancer."},{"key":"B38","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1016\/j.jconrel.2022.10.023","article-title":"Current perspectives and trend of nanomedicine in cancer: a review and bibliometric analysis","volume":"352","author":"Pei","year":"2022","journal-title":"J Control Release."},{"key":"B39","doi-asserted-by":"publisher","first-page":"1089788","DOI":"10.3389\/fsurg.2023.1089788","article-title":"Single-center experience of ex vivo liver resection and autotransplantation for complex hepatic alveolar echinoccosis","volume":"10","author":"Yuan","year":"2023","journal-title":"Front Surg."},{"key":"B40","doi-asserted-by":"publisher","first-page":"2271","DOI":"10.21037\/apm-20-184","article-title":"Current status of ex-vivo liver resection and autologous liver transplantation for end-stage hepatic alveolar echinococcosis","volume":"9","author":"Yang","year":"2020","journal-title":"Ann Palliat Med."},{"key":"B41","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/j.pan.2013.10.009","article-title":"Total pancreatectomy and islet autotransplantation in chronic pancreatitis: recommendations from PancreasFest","volume":"14","author":"Bellin","year":"2014","journal-title":"Pancreatology."},{"key":"B42","doi-asserted-by":"publisher","first-page":"530","DOI":"10.1016\/j.jamcollsurg.2013.12.037","article-title":"Long-term outcomes of total pancreatectomy and islet auto transplantation for hereditary\/genetic pancreatitis","volume":"218","author":"Chinnakotla","year":"2014","journal-title":"J Am Coll Surg."},{"key":"B43","doi-asserted-by":"publisher","first-page":"3262","DOI":"10.1097\/JS9.0000000000000604","article-title":"A novel remnant liver-first strategy for liver autotransplantation in patients with end-stage hepatic alveolar echinococcosis: a retrospective case series","volume":"109","author":"Lv","year":"2023","journal-title":"Int J Surg."},{"key":"B44","doi-asserted-by":"publisher","first-page":"2784","DOI":"10.3390\/ijms26062784","article-title":"Human alveolar echinococcosis-a neglected zoonotic disease requiring urgent attention","volume":"26","author":"Rostami","year":"2025","journal-title":"Int J Mol Sci"},{"key":"B45","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/j.hbpd.2024.12.005","article-title":"Particular Chinese contributions to extracorporeal liver surgery","volume":"24","author":"Aini","year":"2025","journal-title":"Hepatobiliary Pancreat Dis."},{"key":"B46","doi-asserted-by":"publisher","first-page":"762","DOI":"10.1016\/j.pan.2020.04.005","article-title":"The role of total pancreatectomy with islet autotransplantation in the treatment of chronic pancreatitis: a report from the International Consensus Guidelines in chronic pancreatitis","volume":"20","author":"Abu-El-Haija","year":"2020","journal-title":"Pancreatology."},{"key":"B47","doi-asserted-by":"publisher","first-page":"11409","DOI":"10.3389\/ti.2023.11409","article-title":"Improved quality of life among chronic pancreatitis patients undergoing total pancreatectomy with islet autotransplantation-single center experience with large cohort of patients","volume":"36","author":"Coluzzi","year":"2023","journal-title":"Transplant Int."},{"key":"B48","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1080\/17446651.2023.2256407","article-title":"Current practices in islet cell autotransplantation","volume":"18","author":"Chen","year":"2023","journal-title":"Expert Rev Endocrinol Metab."},{"key":"B49","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1016\/S1499-3872(13)60040-5","article-title":"Comprehensive application of modern technologies in precise liver resection","volume":"12","author":"Qian","year":"2013","journal-title":"Hepatobiliary Pancreat Dis."}],"container-title":["Frontiers in Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2025.1537446\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T05:25:44Z","timestamp":1752729944000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2025.1537446\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,17]]},"references-count":49,"alternative-id":["10.3389\/fmed.2025.1537446"],"URL":"https:\/\/doi.org\/10.3389\/fmed.2025.1537446","relation":{},"ISSN":["2296-858X"],"issn-type":[{"value":"2296-858X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,17]]},"article-number":"1537446"}}