{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:17:47Z","timestamp":1787026667482,"version":"build-2736575974"},"reference-count":110,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,5,2]],"date-time":"2025-05-02T00:00:00Z","timestamp":1746144000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:p>Adhesive intestinal obstruction (AIO) represents a common postoperative complication, particularly following abdominal surgery, with reported incidence rates varying between 50 and 80%. Traditional Chinese Medicine (TCM) has proven clinically effective in managing AIO, offering diverse therapeutic approaches that facilitate multi-pathway and multi-target treatment. Clinical evidence consistently supports the favorable safety profile of Traditional Chinese Medicine (TCM). Nevertheless, several critical challenges remain to be addressed, including its complex multi-component nature, insufficiently elucidated mechanisms of action, lack of precise dosage standards, inconsistencies in decoction preparation methods, inconvenient administration procedures, and a paucity of large-scale, multicenter clinical trials with robust evidence. These barriers hinder the widespread adoption and clinical integration of TCM. Moving forward, large-scale, multicenter studies are essential to further investigate the safety and efficacy of TCM. Moreover, reforms in its administration methods and deeper exploration of its mechanisms in AIO treatment are crucial.<\/jats:p>","DOI":"10.3389\/fmed.2025.1573655","type":"journal-article","created":{"date-parts":[[2025,5,2]],"date-time":"2025-05-02T07:42:46Z","timestamp":1746171766000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["Traditional Chinese medicine for adhesive intestinal obstruction: theory, methods and mechanisms of action"],"prefix":"10.3389","volume":"12","author":[{"given":"Pengfei","family":"Zhou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huiju","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiawen","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingming","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuai","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,5,2]]},"reference":[{"key":"ref1","first-page":"D7320","article-title":"Adhesions after abdominal surgery: developments in diagnosis and treatment","volume":"167","author":"Ten Broek","year":"2023","journal-title":"Ned Tijdschr 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