{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T19:58:37Z","timestamp":1791575917722,"version":"4.3.4"},"reference-count":57,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,8,4]],"date-time":"2025-08-04T00:00:00Z","timestamp":1754265600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Worldwide, millions of people suffer from snakebites every year. In Ecuador, as of epidemiological week 30 of 2024, approximately 271 cases have been reported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical case<\/jats:title><jats:p>A 54-year-old male patient suffered a snakebite from the Viperidae family 24\u202fh ago, on his right upper limb. Classified as moderate envenomation, he was given antivenom and admitted to the hospital. During his stay, he began to show clinical and paraclinical alterations, including sinus bradycardia on the electrocardiogram and acute renal injury, requiring dialysis therapy sessions. In daily ECG controls on day 13, the heart rate normalized. However, after day 22, he was discharged but remained under triweekly dialysis therapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Complications from snakebites are rare, both cardiovascular and renal, but can be potentially fatal without early detection and timely treatment.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fmed.2025.1600067","type":"journal-article","created":{"date-parts":[[2025,8,4]],"date-time":"2025-08-04T06:15:55Z","timestamp":1754288155000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Sinus bradycardia and acute renal injury secondary to Viperidae snakebite: first case report"],"prefix":"10.3389","volume":"12","author":[{"given":"El\u00edas David","family":"Guam\u00e1n-Charco","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anabel","family":"Paredes-Ponce","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugo","family":"Orellana-Chimbay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nelson","family":"Omares","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Genesis","family":"Guam\u00e1n-Charco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Rubio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge","family":"Vasconez-Gonzalez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esteban","family":"Ortiz-Prado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,8,4]]},"reference":[{"key":"ref1","volume-title":"Snakebite","year":"2024"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"3829","DOI":"10.1007\/s00467-020-04911-x","article-title":"Snake bite associated with acute kidney injury","volume":"36","author":"Sarkar","year":"2021","journal-title":"Pediatr Nephrol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1016\/j.toxicon.2020.06.009","article-title":"Disorders on cardiovascular parameters in rats and in human blood cells caused by Lachesis acrochorda snake venom","volume":"184","author":"Angel-Camilo","year":"2020","journal-title":"Toxicon"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"1528","DOI":"10.1177\/1535370215590818","article-title":"Bothrops jararaca envenomation: pathogenesis of hemostatic disturbances and intravascular hemolysis","volume":"240","author":"Senise","year":"2015","journal-title":"Exp Biol Med"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"93","DOI":"10.7705\/biomedica.6587","article-title":"Epidemiolog\u00eda y caracter\u00edsticas cl\u00ednicas de las mordeduras de serpientes venenosas en el norte de la Amazon\u00eda del Ecuador (2017-2021)","volume":"43","author":"Calvopi\u00f1a","year":"2023","journal-title":"Biomedica"},{"key":"ref6","volume-title":"Direcci\u00f3n Nacional de Vigilancia Epidemiol\u00f3gica","year":"2024"},{"key":"ref7","volume-title":"Manual de normas y procedimientos sobre prevenci\u00f3n y tratamiento de accidentes ocasionados por mordedura de serpientes","year":"2008"},{"key":"ref8","first-page":"179","article-title":"Insuficiencia card\u00edaca secundaria a mordedura de serpiente. 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