{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T01:22:53Z","timestamp":1755220973859,"version":"3.43.0"},"reference-count":11,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,8,8]],"date-time":"2025-08-08T00:00:00Z","timestamp":1754611200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:p>Embolism has variable manifestations in infective endocarditis (IE) and might be misinterpreted in clinical settings. In this study, we reported the case of a 67-year-old man with erysipelas and septic shock who had developed a new onset of blurred vision and subsequently convulsions and multiple cerebral infarctions. Valve vegetations and patent foramen ovale were negative on the first echocardiography. After the neurologic symptom occurred, repeated echocardiography was performed and revealed vegetations on the mitral valve. As the patient had immunological complications, we suggested prolonged antibiotic therapy, but the patient requested an early discharge due to financial concerns. Under such circumstances, administering a long-acting penicillin G via an intramuscular injection once was an alternative therapy before discharge. For patients with bloodstream infection who develop any new onset symptoms related to arterial occlusion, infective endocarditis should be suspected, and repeated echocardiography is necessary.<\/jats:p>","DOI":"10.3389\/fmed.2025.1605482","type":"journal-article","created":{"date-parts":[[2025,8,8]],"date-time":"2025-08-08T04:10:41Z","timestamp":1754626241000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Case Report: A man with septic shock developed convulsions"],"prefix":"10.3389","volume":"12","author":[{"given":"Linxiang","family":"Huang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peiliang","family":"Gao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xueying","family":"Fu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuran","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jihong","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guiying","family":"Dong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2025,8,8]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1001\/jama.2018.7596","article-title":"Management considerations in infective endocarditis: a review","volume":"320","author":"Wang","year":"2018","journal-title":"JAMA"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"16059","DOI":"10.1038\/nrdp.2016.59","article-title":"Infective endocarditis","volume":"2","author":"Holland","year":"2016","journal-title":"Nat Rev Dis Primers"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"2936","DOI":"10.1161\/01.cir.98.25.2936","article-title":"Diagnosis and management of infective endocarditis and its complications","volume":"98","author":"Bayer","year":"1998","journal-title":"Circulation"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"107749","DOI":"10.1016\/j.clineuro.2023.107749","article-title":"Visual symptoms in acute stroke - A systematic review of observational studies","volume":"229","author":"Helboe","year":"2023","journal-title":"Clin Neurol Neurosurg"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1016\/j.jacc.2016.10.066","article-title":"Challenges in infective endocarditis","volume":"69","author":"Cahill","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"633","DOI":"10.1086\/313753","article-title":"Proposed modifications to the Duke criteria for the diagnosis of infective endocarditis","volume":"30","author":"Li","year":"2000","journal-title":"Clin Infect Dis"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"1743","DOI":"10.1016\/j.ultrasmedbio.2013.03.016","article-title":"Diagnostic value of transthoracic echocardiography for patent foramen ovale: a meta-analysis","volume":"39","author":"Ren","year":"2013","journal-title":"Ultrasound Med Biol"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1038\/nrneurol.2012.183","article-title":"Sepsis-associated encephalopathy","volume":"8","author":"Gofton","year":"2012","journal-title":"Nat Rev Neurol"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1016\/S0140-6736(24)01098-5","article-title":"Infective endocarditis","volume":"404","author":"Li","year":"2024","journal-title":"Lancet"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"1371","DOI":"10.1016\/j.amjmed.2022.06.015","article-title":"Characteristics and diagnostic challenge of antineutrophil cytoplasmic antibody positive infective endocarditis","volume":"135","author":"Ai","year":"2022","journal-title":"Am J Med"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"2917","DOI":"10.1161\/STROKEAHA.113.001602","article-title":"Thrombolysis for ischemic stroke associated with infective endocarditis: results from the nationwide inpatient sample","volume":"44","author":"Asaithambi","year":"2013","journal-title":"Stroke"}],"container-title":["Frontiers in Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2025.1605482\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,8]],"date-time":"2025-08-08T04:10:42Z","timestamp":1754626242000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2025.1605482\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,8]]},"references-count":11,"alternative-id":["10.3389\/fmed.2025.1605482"],"URL":"https:\/\/doi.org\/10.3389\/fmed.2025.1605482","relation":{},"ISSN":["2296-858X"],"issn-type":[{"value":"2296-858X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,8]]},"article-number":"1605482"}}