{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T17:20:34Z","timestamp":1780507234436,"version":"3.54.1"},"reference-count":26,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T00:00:00Z","timestamp":1770336000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"\n Objective<\/jats:title>\n To explore the risk factors of shoulder stiffness after traumatic proximal humeral fracture in patients with osteoporosis, and to develop targeted prevention strategies to provide a basis for clinical optimization of perioperative management.<\/jats:p>\n <\/jats:sec>\n \n Method<\/jats:title>\n A retrospective analysis of 236 patients with osteoporosis and proximal humeral fractures treated from January to December 2024 was performed. According to whether shoulder stiffness occurred at 6\u202fmonths after surgery, they were divided into stiffness group (119 cases) and non-stiffness group (117 cases). Clinical data such as age, body mass index (BMI), smoking history, and preoperative physical therapy were collected. Univariate and multivariate logistic regression analysis were used to analyze risk factors.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n The incidence of shoulder stiffness was 50.4%. Univariate analysis showed that the stiffness group was older (52.83\u202f\u00b1\u202f6.65\u202fyears vs. 43.31\u202f\u00b1\u202f6.48\u202fyears), P24 kg\/m\n 2<\/jats:sup>\n ratio was higher (73.1% vs. 50.4%,\n p<\/jats:italic>\n \u202f&lt;\u202f0.001), more smokers (42.9% vs. 19.7%,\n p<\/jats:italic>\n \u202f&lt;\u202f0.001), and lower preoperative physical therapy rate (10.9% vs. 25.6%,\n p<\/jats:italic>\n \u202f=\u202f0.003). Multivariate analysis confirmed that advanced age (OR\u202f=\u202f1.297), overweight (OR\u202f=\u202f5.599), smoking (OR\u202f=\u202f3.270) and prolonged course of disease (OR\u202f=\u202f2.409) were independent risk factors, while preoperative standardized physical therapy was a protective factor (OR\u202f=\u202f0.187). Subgroup analysis further indicated no significant difference in the incidence of shoulder stiffness between plate and nail fixation methods. ROC curve analysis demonstrated that age and course of disease possessed high predictive value (AUC\u202f=\u202f0.857 and 0.770, respectively), whereas the predictive value of a history of standard physical therapy was relatively low (AUC\u202f=\u202f0.570).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Patients with osteoporosis undergoing surgery for proximal humeral fractures may develop shoulder joint stiffness. To optimize perioperative management, a three-tiered prevention strategy centered on smoking cessation, weight management and early physical therapy is recommended, supplemented by personalized comprehensive preventive measures.<\/jats:p>\n <\/jats:sec>","DOI":"10.3389\/fmed.2025.1641583","type":"journal-article","created":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T06:37:16Z","timestamp":1770359836000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Analysis of risk factors and prevention strategies of shoulder joint stiffness after traumatic proximal humeral fracture in patients with osteoporosis"],"prefix":"10.3389","volume":"12","author":[{"given":"Qiming","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Trauma and Orthopedics, General Hospital of Ningxia Medical University","place":["Yinchuan, Ningxia, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Qin","sequence":"additional","affiliation":[{"name":"Department of Trauma and Orthopedics, General Hospital of Ningxia Medical University","place":["Yinchuan, Ningxia, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Trauma and Orthopedics, General Hospital of Ningxia Medical University","place":["Yinchuan, Ningxia, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiwei","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Trauma and Orthopedics, General Hospital of Ningxia Medical University","place":["Yinchuan, Ningxia, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teng","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Trauma and Orthopedics, General Hospital of Ningxia Medical University","place":["Yinchuan, Ningxia, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Cardiology, General Hospital of Ningxia Medical University","place":["Yinchuan, Ningxia, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,2,6]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"739","DOI":"10.20945\/2359-3997000000563","article-title":"Male osteoporosis","volume":"66","author":"Bandeira","year":"2022","journal-title":"Arch Endocrinol Metab"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"2137","DOI":"10.1007\/s00198-022-06454-3","article-title":"Global, regional prevalence, and risk factors of osteoporosis according to the World Health Organization diagnostic criteria: a systematic review and 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