{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T22:47:04Z","timestamp":1792622824031,"version":"4.5.0"},"reference-count":38,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T00:00:00Z","timestamp":1757462400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>This study aimed to report the preliminary surgical outcomes of a new minimally invasive glaucoma surgery (MIGS), namely trabeculotome tunneling trabeculoplasty (3T) in primary open-angle glaucoma (POAG).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This retrospective observational study with prospective follow-up included POAG patients who underwent 3T surgery at Chengdu First People\u2019s Hospital between December 2022 and June 2024. Postoperative follow-up was conducted at 1\u202fday, 1\u202fweek, 1\u202fmonth, 3\u202fmonths, 6\u202fmonths, and 12\u202fmonths. Evaluations included intraocular pressure (IOP), number of medications, surgical success rate, and postoperative complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Baseline mean IOP was 23.06\u202f\u00b1\u202f0.72\u202fmmHg with a median of 3 (interquartile range, IQR: 2\u20133) medications. Postoperative IOP significantly decreased at all follow-up points except at 1\u202fweek (<jats:italic>p<\/jats:italic>\u202f&amp;lt;\u202f0.05). At 12\u202fmonths, the mean IOP was 16.22\u202f\u00b1\u202f0.76\u202fmmHg with a median of 0 (IQR: 0\u20131) medications. Complete surgical success rates were 80.0% at 6\u202fmonths and 79.8% at 12\u202fmonths. Early postoperative complications included IOP spikes in 34.9% and clinically significant hyphema in 6.3% (all grade 1). Cyclodialysis was rare (1.1%), and no severe adverse events were reported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>3T appears to be a safe and effective surgical option for POAG, providing sustained IOP reduction and medication burden relief with a low incidence of postoperative complications. Larger, controlled studies with longer follow-up are warranted to further validate these findings.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fmed.2025.1641952","type":"journal-article","created":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T05:25:59Z","timestamp":1757481959000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["Safety and effectiveness of a new minimally invasive glaucoma surgery namely trabeculotome tunneling trabeculoplasty in primary open-angle 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