{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T14:53:26Z","timestamp":1776437606639,"version":"3.51.2"},"reference-count":14,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T00:00:00Z","timestamp":1762992000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"\n Introduction<\/jats:title>\n Menstruation marks a significant developmental milestone, typically indicating healthy and normal pubertal changes in females. Primary amenorrhea can arise from various causes, including outflow tract abnormalities, resistant endometrium, primary ovarian insufficiency, and disorders of the hypothalamus, pituitary gland, or other endocrine organs. This report presents an exceptionally rare M\u00fcllerian malformation that does not conform perfectly to existing classification systems, necessitating an individualized management approach.<\/jats:p>\n <\/jats:sec>\n \n Case presentation<\/jats:title>\n We present the case of a 12-year-old girl with a rare M\u00fcllerian malformation, who presented with cyclic lower abdominal pain persisting for over 9 months, with acute exacerbation in the preceding day. Comprehensive clinical evaluation and preoperative pelvic CT imaging revealed multiple anomalies: an unilateral rudimentary horn uterus with cavity and unilateral absence of the ovary and fallopian tube. Digital 3D CT reconstruction was utilized to confirm the diagnosis, revealing a left rudimentary horn uterus with cavity, hydrosalpinx of the left fallopian tube, and absence of the right ovary, fallopian tube and hemi-uterus. Surgical management included laparoscopic resection of the left rudimentary horn uterus and left fallopian tube. Postoperatively, the patient achieved complete resolution of cyclic lower abdominal pain.<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Digital 3D CT reconstruction technology is instrumental in diagnosing rare M\u00fcllerian malformations, providing crucial anatomical insights for surgical planning and patient counseling.<\/jats:p>\n <\/jats:sec>","DOI":"10.3389\/fmed.2025.1657613","type":"journal-article","created":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T06:29:35Z","timestamp":1763015375000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Case Report: Rare M\u00fcllerian malformation assisted by digital 3D CT reconstruction technology for diagnosis and treatment"],"prefix":"10.3389","volume":"12","author":[{"given":"Xiuzhen","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Genhai","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2025,11,13]]},"reference":[{"key":"ref1","first-page":"1374","article-title":"Amenorrhea: evaluation and treatment","volume":"73","author":"Master-Hunter","year":"2006","journal-title":"Am Fam Physician"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1093\/humupd\/dmv048","article-title":"The presentation and management of complex female genital malformations","volume":"22","author":"Aci\u00e9n","year":"2016","journal-title":"Hum Reprod Update"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1007\/s10397-013-0800-x","article-title":"The ESHRE-ESGE consensus on the classification of female genital tract congenital anomalies","volume":"10","author":"Grimbizis","year":"2013","journal-title":"Gynecol Surg"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"1238","DOI":"10.1016\/j.fertnstert.2021.09.025","article-title":"ASRM m\u00fcllerian anomalies classification 2021","volume":"116","author":"Pfeifer","year":"2021","journal-title":"Fertil Steril"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1016\/j.ejogrb.2018.07.007","article-title":"Using 3D MRI can potentially enhance the ability of trained surgeons to more precisely diagnose mullerian duct anomalies compared to MR alone","volume":"228","author":"Pan","year":"2018","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"944","DOI":"10.1016\/s0015-0282(16)59942-7","article-title":"The American Fertility Society. 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