{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T23:02:33Z","timestamp":1792623753359,"version":"4.5.0"},"reference-count":28,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T00:00:00Z","timestamp":1760572800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:p>During last years, new methods of advanced ventilatory monitoring have been introduced to implement lung-protective ventilation. We present a unique case of a 66-year-old female admitted to the ICU with severe unilateral lung injury due to COVID-19 pneumococcal superinfection. By combining electrical impedance tomography (EIT) and esophageal pressure measurements, individualized positive end-expiratory pressure (PEEP) titration was performed. Initially, high PEEP levels (18 cmH<jats:sub>2<\/jats:sub>O) were optimal. Over the course of a week, reflecting dynamic lung recovery, PEEP levels could be reduced to 8 cmH<jats:sub>2<\/jats:sub>O followed by extubation. This case emphasizes the importance of personalized PEEP titration in managing asymmetric lung injury, highlighting how EIT-based monitoring can optimize alveolar recruitment while minimizing overdistension.<\/jats:p>","DOI":"10.3389\/fmed.2025.1675679","type":"journal-article","created":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T05:32:02Z","timestamp":1760592722000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Electrical impedance tomography to guide mechanical ventilation for asymmetrical lung injury: a case report"],"prefix":"10.3389","volume":"12","author":[{"given":"Albina","family":"Musaj","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louis","family":"Tronchet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corstiaan","family":"den 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