{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T16:24:42Z","timestamp":1785860682364,"version":"3.56.0"},"reference-count":30,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T00:00:00Z","timestamp":1760486400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>Adenomyosis is a chronic gynecological disorder characterized by the infiltration of ectopic endometrial tissue into the myometrium, affecting approximately 20\u201335% of women of reproductive age. Although hormonal therapy and surgery are common treatments, their side effects and impact on fertility highlight the need for alternative approaches. Recently, integrative medicine, including traditional Korean medicine, has gained attention. However, well-documented long-term case studies using objective imaging are limited.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A 40-year-old woman with severe adenomyosis symptoms unresponsive to conventional therapies received long-term herbal medicine based on modified Bojungikgi-tang, with regular ultrasound monitoring and clinical assessments over 12\u202fmonths.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>After treatment, menstrual pain decreased from a numeric rating scale score of 7\u20138 to 1\u20132, hemoglobin normalized, and ultrasonography revealed reduced adenomyosis and improved uterine structure. The patient\u2019s quality of life improved markedly with no adverse effects.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This case suggests that herbal medicine may be a safe and effective option for managing adenomyosis, supporting further research into integrative treatment strategies.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fmed.2025.1679449","type":"journal-article","created":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T05:42:05Z","timestamp":1760506925000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Management of symptoms of suspected adenomyosis uteri using herbal medicine modified Bojungikgi-tang: a case report with ultrasound monitoring"],"prefix":"10.3389","volume":"12","author":[{"given":"Hyunsuk","family":"Park","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyein","family":"Jeong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyeong Han","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung Jeong","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stella","family":"Roh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,10,15]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1055\/s-0040-1718920","article-title":"Epidemiology of adenomyosis","volume":"38","author":"Upson","year":"2020","journal-title":"Semin Reprod 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