{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T20:42:18Z","timestamp":1757623338907,"version":"3.44.0"},"reference-count":30,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T00:00:00Z","timestamp":1757376000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>The aim of this study is to evaluate sarcopenia in female patients with Fibromyalgia Syndrome (FMS), according to diagnostic algorithms, in terms of total and regional muscle mass measurements.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study included 60 female patients diagnosed with FMS (mean [M]\u202f=\u202f47.78\u202fyears, Standard deviation [SD]\u202f=\u202f4.72\u202fyears) and 30 healthy women (M\u202f=\u202f49.8\u202fyears, SD\u202f=\u202f4.8\u202fyears). The ages and anthropometric measurements were noted, and participants evaluated using the Widespread Pain Index, Symptom Severity Scale, Visual Analog Scale, Fatigue Severity Scale, Beck Depression Inventory, International Physical Activity Questionnaire, and the Fibromyalgia Impact Questionnaire.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The hand grip strength and gait speed values of the patient group were found to be lower than those of the control group, and the chair stand test value higher than that of the control group. There was a statistically significant difference between the groups (<jats:italic>p<\/jats:italic>\u202f&amp;lt;\u202f0.01). Two individuals in the patient group were classified as having sarcopenia according to the ISarcoPRM algorithm. No statistically significant difference was found between the patient group and the control group in terms of anterior thigh muscle thickness, sonographic thigh adjustment ratio, and skeletal muscle mass index (<jats:italic>p<\/jats:italic>\u202f=\u202f0.897, <jats:italic>p<\/jats:italic>\u202f=\u202f0.829, <jats:italic>p<\/jats:italic>\u202f=\u202f0.706).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The female patients with FMS were dynapenic, which means a loss of muscle function without a loss of muscle mass.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fmed.2025.1680355","type":"journal-article","created":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T05:56:51Z","timestamp":1757397411000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of sarcopenia in female patients with fibromyalgia syndrome: an ultrasonographic approach"],"prefix":"10.3389","volume":"12","author":[{"given":"Salih","family":"Karvanli","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serdar","family":"Karakose","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hatice","family":"Ugurlu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2025,9,9]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"ITC33-ITC48","DOI":"10.7326\/AITC202003030","article-title":"Fibromyalgia","volume":"172","author":"Bair","year":"2020","journal-title":"Ann Intern Med"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"1857","DOI":"10.1093\/brain\/awt053","article-title":"Small fibre pathology in patients with fibromyalgia syndrome","volume":"136","author":"\u00dc\u00e7eyler","year":"2013","journal-title":"Brain"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1007\/s00281-018-0672-2","article-title":"Neurogenic inflammation in fibromyalgia","volume":"40","author":"Littlejohn","year":"2018","journal-title":"Semin Immunopathol"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1007\/978-981-19-7376-5_16","article-title":"A link between inflammatory mechanisms and fibromyalgia","volume":"1411","author":"Bains","year":"2023","journal-title":"Adv Exp Med Biol"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"155557","DOI":"10.1016\/j.metabol.2023.155557","article-title":"Sarcopenia in youth","volume":"144","author":"Jung","year":"2023","journal-title":"Metabolism"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1007\/s00296-021-04973-6","article-title":"Assessment of sarcopenia in patients with fibromyalgia","volume":"42","author":"Kapuczinski","year":"2022","journal-title":"Rheumatol Int"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"816","DOI":"10.1007\/s00508-015-0821-8","article-title":"The evaluation in terms of sarcopenia of patients with fibromyalgia syndrome","volume":"128","author":"Koca","year":"2016","journal-title":"Wien Klin Wochenschr"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"703","DOI":"10.23736\/S1973-9087.24.08348-5","article-title":"Risk of secondary sarcopenia in Europeans with fibromyalgia according to the EWGSOP2 guidelines: systematic review and meta-analysis","volume":"60","author":"Rodr\u00edguez-Lumbreras","year":"2024","journal-title":"Eur J Phys Rehabil Med"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"5552","DOI":"10.3390\/jcm10235552","article-title":"Sarcopenia: diagnosis and management, state of the art and contribution of ultrasound","volume":"10","author":"Giovannini","year":"2021","journal-title":"J Clin Med"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"902","DOI":"10.1097\/PHM.0000000000001439","article-title":"STAR-sonographic thigh adjustment ratio: a Golden formula for the diagnosis of sarcopenia","volume":"99","author":"Kara","year":"2020","journal-title":"Am J Phys Med Rehabil"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"jrm00209","DOI":"10.2340\/16501977-2851","article-title":"Diagnosing sarcopenia: functional perspectives and a new algorithm from the ISarcoPRM","volume":"53","author":"Kara","year":"2021","journal-title":"J Rehabil Med"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1016\/j.semarthrit.2016.08.012","article-title":"2016 revisions to the 2010\/2011 fibromyalgia diagnostic criteria","volume":"46","author":"Wolfe","year":"2016","journal-title":"Semin Arthritis Rheum"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1001\/archneur.1989.00520460115022","article-title":"The fatigue severity scale. 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