{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T04:48:49Z","timestamp":1770353329783,"version":"3.49.0"},"reference-count":24,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T00:00:00Z","timestamp":1764633600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:p>Pulmonary Lymphatic Perfusion Syndrome (PLPS) is a rare condition characterized by abnormal lymphatic drainage into the lungs, leading to symptoms such as chyloptysis and chylous effusions. We report a case of a 54-year-old male with PLPS who presented with persistent cough, milky sputum, and pericardial effusion. Following initial misdiagnosis and ineffective empirical treatment for a presumed pulmonary infection, a definitive diagnosis of PLPS was established. The patient underwent successful percutaneous thoracic duct embolization, resulting in complete resolution of symptoms and imaging findings at follow-up. This case highlights the importance of considering PLPS in patients with unexplained chylous effusions and the efficacy of lymphatic intervention as a treatment option.<\/jats:p>","DOI":"10.3389\/fmed.2025.1696594","type":"journal-article","created":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T05:14:14Z","timestamp":1764652454000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Successful treatment of pulmonary lymphatic perfusion syndrome with lymphatic intervention embolization: a case 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