{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T10:57:31Z","timestamp":1783421851240,"version":"3.54.6"},"reference-count":34,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T00:00:00Z","timestamp":1764720000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:p>\n                    Bloodstream infections caused by anaerobic bacteria present a serious threat to patients. Rapid and accurate diagnosis is crucial for treatment and patient prognosis. Herein, we report a rare case of\n                    <jats:italic>Clostridium paraputrificum<\/jats:italic>\n                    bacteremia in an 82-year-old woman who developed an infection after undergoing necrotic small bowel resection. The patient was treated with 5-day anti-infective therapy with meropenem and linezolid, successfully controlling the disease. We also constructed a phylogenetic tree with other similar bacteria using gene sequencing and showed the virulence and antimicrobial resistance of\n                    <jats:italic>C. paraputrificum<\/jats:italic>\n                    . Additionally, the clinical features and antibiotic treatment of this case were reviewed and discussed in the existing literature. This case and review illustrate the insidious nature of\n                    <jats:italic>C. paraputrificum<\/jats:italic>\n                    infections, emphasizing the need for greater clinician awareness and improved diagnostic and treatment strategies.\n                  <\/jats:p>","DOI":"10.3389\/fmed.2025.1702526","type":"journal-article","created":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T06:40:28Z","timestamp":1764744028000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["A rare case of Clostridium paraputrificum bloodstream infection in a patient with intestinal necrosis: case report and literature review"],"prefix":"10.3389","volume":"12","author":[{"given":"Caixia","family":"Ji","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ke","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zongyao","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Jianfei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yayun","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziqian","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,12,3]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"2912","DOI":"10.1096\/fj.201902861R","article-title":"Gradual 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