{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T07:16:39Z","timestamp":1767683799247,"version":"3.48.0"},"reference-count":25,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T00:00:00Z","timestamp":1767657600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:p>\n                    Over the past decade,\n                    <jats:italic>Shewanella<\/jats:italic>\n                    spp. have been increasingly recognized as opportunistic pathogens, particularly in patients with malignancies, neutropenia, severe heart failure, renal insufficiency, and hepatobiliary diseases.\n                    <jats:italic>Shewanella indica<\/jats:italic>\n                    is a rarely reported species within the\n                    <jats:italic>Shewanella<\/jats:italic>\n                    genus, and its role in human infection remains poorly documented. In this study, we report the first case of\n                    <jats:italic>S. indica<\/jats:italic>\n                    isolated from the stool of a critically ill 72-year-old man in Serbia with multiple pre-existing comorbidities and co-infections. Initial identification using the VITEK 2 system misclassified the strain as\n                    <jats:italic>Shewanella algae<\/jats:italic>\n                    , while species-level identification by the matrix-assisted laser desorption\/ionization-time-of-flight mass spectrometry (MALDI-TOF MS) was inconclusive. However, whole-genome sequencing (WGS) definitively identified the isolate as\n                    <jats:italic>S. indica<\/jats:italic>\n                    and revealed a multidrug-resistant profile together with numerous virulence-associated genes. Minimum inhibitory concentrations (MICs) were determined for 32 antibiotics, although interpretation was constrained by the lack of species-specific breakpoints. This case highlights the diagnostic challenges in differentiating\n                    <jats:italic>Shewanella indica<\/jats:italic>\n                    , discusses its possible clinical roles, and underscores the value of genomic tools for accurate identification. It also reinforces the importance of recognizing rare pathogens in complex clinical scenarios.\n                  <\/jats:p>","DOI":"10.3389\/fmed.2025.1715579","type":"journal-article","created":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T07:11:42Z","timestamp":1767683502000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["First case report of Shewanella indica isolated from a hospitalized patient in Serbia"],"prefix":"10.3389","volume":"12","author":[{"given":"Brankica","family":"Filipi\u0107","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vladimir","family":"\u017dugi\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Majda","family":"Golob","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martina Hrast","family":"Rambaher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lidija","family":"Bo\u0161kovi\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marina T.","family":"Milenkovi\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2026,1,6]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"1115","DOI":"10.3390\/microorganisms13051115","article-title":"Characterization of antibiotic resistance in Shewanella species: an emerging pathogen in clinical and environmental settings","volume":"13","author":"Sher","year":"2025","journal-title":"Microorganisms"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"1515","DOI":"10.1080\/21505594.2022.2117831","article-title":"Shewanella infection in humans: epidemiology, clinical features and 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