{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T04:55:34Z","timestamp":1768280134354,"version":"3.49.0"},"reference-count":18,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T00:00:00Z","timestamp":1768176000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:p>\n                    Autoimmune gastritis (AIG) is an under-recognized, corpus-predominant autoimmune loss of oxyntic glands that creates a metaplastic, inflamed field in which hyperplastic polyps are common, while epithelial dysplasia is uncommon but management-defining. We report a 35-year-old woman with corpus-predominant atrophy and three pedunculated polyps removed by endoscopic mucosal resection (EMR); initial pathology called a hyperplastic polyp with focal low-grade dysplasia (LGD). On tertiary review, the background was identified as AIG (corpus-restricted oxyntic atrophy with pseudopyloric, also called oxyntic, metaplasia and mild intestinal metaplasia) and a small polyp-head focus was upgraded to high-grade dysplasia (HGD); margins were negative.\n                    <jats:italic>Helicobacter pylori<\/jats:italic>\n                    was negative on histology\/immunohistochemistry and urea breath testing. Targeted serology at index and follow-up showed persistently elevated anti-parietal-cell antibodies and fasting gastrin, with intrinsic-factor antibody negative and vitamin B\n                    <jats:sub>12<\/jats:sub>\n                    within range. Early follow-up confirmed a healed EMR site with a persistent corpus-predominant background, and a small body polyp that proved to be a hyperplastic polyp without dysplasia. This case highlights that concurrent AIG and HGD shift management from routine post-polypectomy care to definitive excision plus corpus-focused surveillance, and it argues for actively considering AIG when dysplasia is found in a body polyp\u2014and considering dysplasia when AIG is present.\n                  <\/jats:p>","DOI":"10.3389\/fmed.2025.1716969","type":"journal-article","created":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T08:12:59Z","timestamp":1768205579000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Case Report: Concurrent autoimmune gastritis and high-grade dysplasia in a gastric hyperplastic 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