{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T06:46:19Z","timestamp":1766040379560,"version":"3.48.0"},"reference-count":11,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T00:00:00Z","timestamp":1766016000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"\n Background<\/jats:title>\n \n Central Serous Retinopathy (CSR) is a retinal disorder characterized by serous detachment of the neurosensory retina, commonly associated with psychological stress and Type A personality traits. From an Ayurvedic perspective, these features correspond to Vata predominance, marked by hyperactivity, anxiety, and autonomic instability. Such individuals may be constitutionally predisposed to disorders of Vata imbalance, including retinal pathologies resembling\n Vataja Shopha<\/jats:italic>\n . This case series explores therapeutic outcomes of Ayurvedic management in CSR among individuals with\n Vata Prakriti<\/jats:italic>\n .\n <\/jats:p>\n <\/jats:sec>\n \n Case presentation<\/jats:title>\n \n Three patients-two males (aged 65 and 46 years) and one female (aged 40 years), diagnosed with CSR and confirmed as\n Vata Prakriti<\/jats:italic>\n through a standardized questionnaire, were treated with an identical Ayurvedic regimen comprising\n Ashwagandha<\/jats:italic>\n tablets,\n Punarnavadi Kashaya, Tiktaka Ghrita, Kalyanaka Ghrita<\/jats:italic>\n , and\n Triphala Churna<\/jats:italic>\n . Local ocular therapies included\n Shiro Pichu<\/jats:italic>\n with\n Brahmi Ghrita, Pratimarsha Nasya<\/jats:italic>\n with\n Anu Taila<\/jats:italic>\n , and\n Anjana Karma<\/jats:italic>\n with\n Elaneer Kozhumbu<\/jats:italic>\n . Lifestyle advice emphasized regular sleep, timely meals, guided meditation, and reduced screen exposure. All three patients demonstrated marked improvement in visual acuity and complete anatomical resolution of macular fluid on Optical Coherence Tomography within 4\u201317 months. No recurrence was observed over 1 year of follow-up.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n This case series highlights a possible association between CSR and\n Vata Prakriti<\/jats:italic>\n . Vata pacifying and\n Rasayana<\/jats:italic>\n based Ayurvedic interventions showed favorable visual and structural outcomes. Incorporating\n Prakriti<\/jats:italic>\n phenotyping in ocular disease management may enhance personalized, integrative approaches to retinal disorders.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.3389\/fmed.2025.1722235","type":"journal-article","created":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T06:43:14Z","timestamp":1766040194000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Prakriti phenotyping in Central Serous Retinopathy (CSR): case series on Ayurvedic therapeutic outcomes in Vata individuals"],"prefix":"10.3389","volume":"12","author":[{"given":"Shanti.","family":"K","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gopinathan.","family":"G","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2025,12,18]]},"reference":[{"key":"B1","first-page":"14","article-title":"Central serous chorioretinopathy: pathophysiology and management","volume":"10","year":"2023","journal-title":"Eye Vis (Lond)"},{"key":"B2","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1097\/00006982-198700720-00009","article-title":"Type-A behavior and central serous chorioretinopathy","volume":"7","author":"Yannuzzi","year":"1987","journal-title":"Retina."},{"key":"B3","doi-asserted-by":"publisher","first-page":"S60","DOI":"10.4103\/IJO.IJO_1180_23","article-title":"Association of central serous chorioretinopathy with type of personality, anxiety and depression","volume":"72","author":"Mukherji","year":"2024","journal-title":"Indian J Ophthalmol."},{"key":"B4","doi-asserted-by":"publisher","first-page":"930","DOI":"10.4103\/IJO.IJO_267_25","article-title":"Central serous chorioretinopathy and autonomic dysfunction","volume":"73","author":"Dudani","year":"2025","journal-title":"Indian J Ophthalmol."},{"key":"B5","doi-asserted-by":"publisher","first-page":"3474","DOI":"10.1167\/iovs.05-1246","article-title":"Sympathetic-parasympathetic activity and reactivity in central serous chorioretinopathy: a case-control study","volume":"47","author":"Tewari","year":"2006","journal-title":"Invest Ophthalmol Vis Sci."},{"key":"B6","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/j.survophthal.2012.07.004","article-title":"Central serous chorioretinopathy: update on pathophysiology and treatment","volume":"58","author":"Nicholson","year":"2013","journal-title":"Surv Ophthalmol."},{"key":"B7","first-page":"38","article-title":"A deep dive on central serous chorioretinopathy","author":"Nicholson","year":"2018","journal-title":"Retina Today"},{"key":"B8","first-page":"799","volume":"816","author":"Paradakara","year":"2010","journal-title":"AstangaHridaya of Vagbhatta, Nidanasthana (13\/21, 13\/22)"},{"key":"B9","first-page":"691","author":"Kushwaha","year":"2014","journal-title":"Charaka Samhita, Vimanasthana (08\/101)"},{"key":"B10","first-page":"903","author":"Paradakara","year":"2010","journal-title":"AstangaHridaya of Vagbhatta, Utharasthana (12\/08)"},{"key":"B11","doi-asserted-by":"publisher","first-page":"1057","DOI":"10.3390\/pharmaceutics15041057","article-title":"Ashwagandha (Withania somnifera)-current research on the health-promoting activities: a narrative review","volume":"15","author":"Mikulska","year":"2023","journal-title":"Pharmaceutics."}],"container-title":["Frontiers in Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2025.1722235\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T06:43:18Z","timestamp":1766040198000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2025.1722235\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,18]]},"references-count":11,"alternative-id":["10.3389\/fmed.2025.1722235"],"URL":"https:\/\/doi.org\/10.3389\/fmed.2025.1722235","relation":{},"ISSN":["2296-858X"],"issn-type":[{"value":"2296-858X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,18]]},"article-number":"1722235"}}