{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T16:47:38Z","timestamp":1793119658542,"version":"4.5.0"},"reference-count":14,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T00:00:00Z","timestamp":1770681600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"\n Introduction<\/jats:title>\n Mucormycosis is a catastrophic fungal infection in immunocompromised patients and has a high mortality rate. Amphotericin B colloidal dispersions have demonstrated clinical efficacy in the treatment of mucormycosis; however, there is limited literature on the management of severe skin damage secondary to the extravasation of amphotericin B colloidal dispersions.<\/jats:p>\n <\/jats:sec>\n \n Case presentation<\/jats:title>\n A 36-year-old diabetic woman with severe pulmonary mucormycosis developed skin damage on her left foot after 34\u202fdays of amphotericin B colloidal dispersion treatment via a peripheral vein. The medication was switched to a central vein, and nursing interventions, including silver alginate ion dressing and saline wet compress, successfully managed the injury. By day 155, the skin had completely healed with minimal residual pigmentation.<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n This case report describes the management of a severe skin injury caused by amphotericin B colloidal dispersion extravasation in an immunocompromised patient, carried out by bedside nurses.<\/jats:p>\n <\/jats:sec>\n \n Relevance for clinical practice<\/jats:title>\n This study presents an effective management strategy for skin damage caused by amphotericin B colloidal dispersions extravasation, emphasizing timely intervention and optimizing care for patients receiving prolonged or high-dose therapy.<\/jats:p>\n <\/jats:sec>","DOI":"10.3389\/fmed.2025.1723602","type":"journal-article","created":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T05:30:34Z","timestamp":1770701434000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Nursing management of pulmonary mucormycosis with skin damage secondary to amphotericin B colloidal dispersion: a case report"],"prefix":"10.3389","volume":"12","author":[{"given":"Yu","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine, Shengjing Hospital of China Medical University","place":["Shenyang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine, Shengjing Hospital of China Medical University","place":["Shenyang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiyao","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine, Shengjing Hospital of China Medical University","place":["Shenyang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,2,10]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"1415","DOI":"10.1007\/s00134-017-4857-2","article-title":"Focus on immunocompromised patients","volume":"43","author":"Darmon","year":"2017","journal-title":"Intensive Care Med"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"1896","DOI":"10.1016\/j.chest.2020.05.598","article-title":"Treatment of community-acquired pneumonia in immunocompromised adults: a consensus statement regarding initial strategies","volume":"158","author":"Ramirez","year":"2020","journal-title":"Chest"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1016\/j.idc.2021.03.009","article-title":"Mucormycosis","volume":"35","author":"Steinbrink","year":"2021","journal-title":"Infect Dis Clin N 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infection control and healing: review of the literature","volume":"33","author":"Atiyeh","year":"2007","journal-title":"Burns"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1016\/j.jtv.2023.03.003","article-title":"Moist dressings in the treatment of pressure injuries: a network meta-analysis","volume":"32","author":"Geng","year":"2023","journal-title":"J Tissue Viability"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"5857","DOI":"10.1002\/nop2.1867","article-title":"Efficacy of different types of dressings on pressure injuries: systematic review and network meta-analysis","volume":"10","author":"Zhang","year":"2023","journal-title":"Nurs Open"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"1414","DOI":"10.1016\/j.ijbiomac.2020.07.311","article-title":"Alginate hydrogel dressings for advanced wound management","volume":"162","author":"Zhang","year":"2020","journal-title":"Int J Biol Macromol"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"856","DOI":"10.1038\/s41423-019-0252-y","article-title":"GnRH impairs diabetic wound healing through enhanced NETosis","volume":"17","author":"Lee","year":"2020","journal-title":"Cell Mol Immunol"}],"container-title":["Frontiers in Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2025.1723602\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T05:30:35Z","timestamp":1770701435000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2025.1723602\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,10]]},"references-count":14,"alternative-id":["10.3389\/fmed.2025.1723602"],"URL":"https:\/\/doi.org\/10.3389\/fmed.2025.1723602","relation":{},"ISSN":["2296-858X"],"issn-type":[{"value":"2296-858X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,10]]},"article-number":"1723602"}}