{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T17:58:06Z","timestamp":1766167086951,"version":"3.48.0"},"reference-count":42,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T00:00:00Z","timestamp":1765324800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Segmental rim defect (SRD) of the acetabulum is a common type of osteolysis following primary total hip arthroplasty. Accurate quantitative evaluation of severity and morphology of the SRD can provide critical information to surgeons for decision-making on surgical reconstruction. Therefore, we aim to investigate the effect of morphologic features of SRDs on the press-fit stability of cementless cups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A 3D finite element model of Sawbones hemipelvic bone was developed using CT scan. Submodels with varying SRD geometries and locations were created, followed by Boolean reaming and virtual 1-mm press-fit implantation of a cementless cup. The press-fit stability was evaluated by using the push-out and lever-out tests based on quasi-static non-linear finite element analysis. The peak micromotion (PM) levels of all submodels at the bone-cup interface during the gait cycle were also compared.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Despite the depth and width, the defect in the weight-bearing zone exhibited the lowest average push-out load of 2429 \u00b1 294.19 N and lever-out moment of 100 \u00b1 8.40 Nm comparing to those in other zones. The maximal push-out and lever-out loads of the cup decreased as either the width or depth of defect increased. The percentages of strength reduction for push-out and lever-out tests, respectively up to 47.8 and 34.1%, were significantly higher in the weight-bearing zone comparing to those in the other zones. During the gait cycle, all worst-scenario defects resulted in varying levels of increase in interfacial PM comparing to the intact acetabular rim. In the second half of the gait cycle, the defect in the weight-bearing zone produced the highest level of PM.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In revision total hip arthroplasty (r-THA), a large SRD in the weight-bearing zone can result in the utmost loss of press-fit stability and a detrimental interfacial micromotion, which may lead to early loosening of the cup. Thus, an accurate quantitative evaluation of defect morphology is valuable for surgeons to develop a refined plan for reconstruction of initial stability of a cementless cup.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fmed.2025.1729549","type":"journal-article","created":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T06:35:44Z","timestamp":1765348544000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Effect of segmental rim defect morphology on press-fit stability of the cementless acetabular cup: a finite element analysis"],"prefix":"10.3389","volume":"12","author":[{"given":"Xin","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kewei","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bolin","family":"Feng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haicong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huan","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanbin","family":"Ouyang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2025,12,10]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"780","DOI":"10.2106\/JBJS.F.00222","article-title":"Projections of primary and revision hip and knee arthroplasty in the United States from 2005 to 2030.","volume":"89","author":"Kurtz","year":"2007","journal-title":"J Bone Joint Surg Am."},{"key":"B2","doi-asserted-by":"publisher","first-page":"935","DOI":"10.1186\/s12891-022-05885-7","article-title":"Classification and reconstruction of femoral bone defect in the revision of aseptic loosening of distal femoral endoprostheses: a 10-year multicenter retrospective analysis.","volume":"23","author":"Hou","year":"2022","journal-title":"BMC Musculoskelet Disord."},{"key":"B3","doi-asserted-by":"publisher","first-page":"179","DOI":"10.15386\/mpr-2136","article-title":"Causes of revision after total hip arthroplasty in an orthopedics and traumatology regional center.","volume":"95","author":"Oltean-Dan","year":"2022","journal-title":"Med Pharm Rep."},{"key":"B4","doi-asserted-by":"publisher","first-page":"5624","DOI":"10.3390\/ijerph17155624","article-title":"Synthetic bone grafting in aseptic loosening of acetabular cup: good clinical and radiological outcomes in contained bone defects at medium-term follow up.","volume":"17","author":"Parchi","year":"2020","journal-title":"Int J Environ Res Public Health."},{"key":"B5","doi-asserted-by":"publisher","first-page":"1494","DOI":"10.1016\/j.arth.2022.02.060","article-title":"Diagnosis and detection of subtle aseptic loosening in total hip arthroplasty.","volume":"37","author":"Anil","year":"2022","journal-title":"J Arthroplasty."},{"key":"B6","first-page":"7080","article-title":"Primary total hip arthroplasty failure: aseptic loosening remains the most common cause of revision.","volume":"15","author":"Feng","year":"2022","journal-title":"Am J Transl Res."},{"key":"B7","doi-asserted-by":"publisher","first-page":"32","DOI":"10.2340\/17453674.2023.26190","article-title":"Radiographic signs and hip pain 5 years after THA with a cemented stem predict future revision for aseptic loosening: a prospective cohort study.","volume":"95","author":"L\u00fcbbeke","year":"2024","journal-title":"Acta Orthop."},{"key":"B8","doi-asserted-by":"publisher","first-page":"1275086","DOI":"10.3389\/fcimb.2023.1275086","article-title":"Nano wear particles and the periprosthetic microenvironment in aseptic loosening induced osteolysis following joint arthroplasty.","volume":"13","author":"Xie","year":"2023","journal-title":"Front Cell Infect Microbiol."},{"key":"B9","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1186\/s40779-022-00404-0","article-title":"Propionate and butyrate attenuate macrophage pyroptosis and osteoclastogenesis induced by CoCrMo alloy particles.","volume":"9","author":"Wu","year":"2022","journal-title":"Mil Med Res."},{"key":"B10","doi-asserted-by":"publisher","first-page":"128","DOI":"10.5435\/JAAOS-21-03-128","article-title":"Acetabular bone loss in revision total hip arthroplasty: evaluation and management.","volume":"21","author":"Sheth","year":"2013","journal-title":"J Am Acad Orthop Surg."},{"key":"B11","doi-asserted-by":"publisher","first-page":"799443","DOI":"10.3389\/fbioe.2022.799443","article-title":"Acetabular revision arthroplasty based on 3-dimensional reconstruction technology using jumbo cups.","volume":"10","author":"Shen","year":"2022","journal-title":"Front Bioeng Biotechnol."},{"key":"B12","doi-asserted-by":"publisher","first-page":"432","DOI":"10.1007\/s00132-020-03895-8","article-title":"Acetabular defect classification and management : Revision arthroplasty of the acetabular cup based on 3-point fixation.","volume":"49","author":"Ghanem","year":"2020","journal-title":"Orthopade."},{"key":"B13","doi-asserted-by":"publisher","first-page":"1154","DOI":"10.1007\/s11999-016-5169-5","article-title":"One-third of hips after periacetabular osteotomy survive 30 years with good clinical results, no progression of arthritis, or conversion to THA.","volume":"475","author":"Lerch","year":"2017","journal-title":"Clin Orthop Relat Res."},{"key":"B14","doi-asserted-by":"publisher","first-page":"1912","DOI":"10.1111\/os.13368","article-title":"Revision total hip arthroplasty with severe acetabular defect: a preliminary exploration and attempt of robotic-assisted technology.","volume":"14","author":"Zhang","year":"2022","journal-title":"Orthop Surg."},{"key":"B15","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1007\/s00402-019-03318-0","article-title":"Mid-term results after revision total hip arthroplasty with custom-made acetabular implants in patients with Paprosky III acetabular bone loss.","volume":"140","author":"Fr\u00f6schen","year":"2020","journal-title":"Arch Orthop Trauma Surg."},{"key":"B16","doi-asserted-by":"publisher","first-page":"929103","DOI":"10.3389\/fsurg.2022.929103","article-title":"Clinical and radiological outcomes of jumbo cup in revision total hip arthroplasty: a systematic review.","volume":"9","author":"Wang","year":"2022","journal-title":"Front Surg."},{"key":"B17","doi-asserted-by":"publisher","first-page":"1515","DOI":"10.1007\/s00264-022-05353-w","article-title":"Porous tantalum shell and augment for acetabular defect reconstruction in revision total hip arthroplasty: a mid-term follow-up study.","volume":"46","author":"Alqwbani","year":"2022","journal-title":"Int Orthop."},{"key":"B18","doi-asserted-by":"publisher","first-page":"823","DOI":"10.1016\/j.arth.2017.10.031","article-title":"Acetabular revision using trabecular metal augments for paprosky type 3 defects.","volume":"33","author":"O\u2019Neill","year":"2018","journal-title":"J Arthroplasty."},{"key":"B19","doi-asserted-by":"publisher","first-page":"6403","DOI":"10.1007\/s00402-023-04843-9","article-title":"Outcome of different reconstruction options using allografts in revision total hip arthroplasty for severe acetabular bone loss: a systematic review and meta-analysis.","volume":"143","author":"Strahl","year":"2023","journal-title":"Arch Orthop Trauma Surg."},{"key":"B20","doi-asserted-by":"publisher","first-page":"890","DOI":"10.1054\/arth.2000.8323","article-title":"Radiographic anatomic structure of the arthritic acetabulum and its influence on total hip arthroplasty.","volume":"15","author":"Dorr","year":"2000","journal-title":"J Arthroplasty."},{"key":"B21","doi-asserted-by":"publisher","first-page":"1720","DOI":"10.1016\/j.arth.2020.01.019","article-title":"Fixation stability of uncemented acetabular cups with respect to different bone defect sizes.","volume":"35","author":"Schulze","year":"2020","journal-title":"J Arthroplasty."},{"key":"B22","doi-asserted-by":"publisher","first-page":"1177","DOI":"10.1016\/j.clinbiomech.2014.09.006","article-title":"Factors influencing initial cup stability in total hip arthroplasty.","volume":"29","author":"Amirouche","year":"2014","journal-title":"Clin Biomech."},{"key":"B23","doi-asserted-by":"publisher","first-page":"104607","DOI":"10.1016\/j.compbiomed.2021.104607","article-title":"Determinants of the primary stability of cementless acetabular cup implants: a 3D finite element study.","volume":"135","author":"Immel","year":"2021","journal-title":"Comput Biol Med."},{"key":"B24","doi-asserted-by":"publisher","first-page":"1527","DOI":"10.1007\/s00264-016-3369-y","article-title":"Segmental acetabular rim defects, bone loss, oversizing, and press fit cup in total hip arthroplasty evaluated with a probabilistic finite element analysis.","volume":"41","author":"Amirouche","year":"2017","journal-title":"Int Orthop."},{"key":"B25","doi-asserted-by":"crossref","first-page":"217","DOI":"10.2106\/00004623-197860020-00014","article-title":"Dislocations after total hip-replacement arthroplasties.","volume":"60","author":"Lewinnek","year":"1978","journal-title":"J Bone Joint Surg Am."},{"key":"B26","doi-asserted-by":"publisher","first-page":"888","DOI":"10.1186\/s13018-024-05389-1","article-title":"Morphological and bone defect mapping analysis of true acetabulum in Crowe type IV hip dysplasia.","volume":"19","author":"Yang","year":"2024","journal-title":"J Orthop Surg Res."},{"key":"B27","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1007\/s00132-016-3378-y","article-title":"Acetabular defect classification in times of 3D imaging and patient-specific treatment protocols.","volume":"46","author":"Horas","year":"2017","journal-title":"Orthopade."},{"key":"B28","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1016\/j.cmpb.2006.08.002","article-title":"The relation between micromotion and screw fixation in acetabular cup.","volume":"84","author":"Hsu","year":"2006","journal-title":"Comput Methods Programs Biomed."},{"key":"B29","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1080\/10255842.2018.1524884","article-title":"Calibration of crushable foam plasticity models for synthetic bone material for use in finite element analysis of acetabular cup deformation and primary stability.","volume":"22","author":"Schulze","year":"2019","journal-title":"Comput Methods Biomech Biomed Engin."},{"key":"B30","doi-asserted-by":"publisher","first-page":"859","DOI":"10.1016\/s0021-9290(01)00040-9","article-title":"Hip contact forces and gait patterns from routine activities.","volume":"34","author":"Bergmann","year":"2001","journal-title":"J Biomech."},{"key":"B31","doi-asserted-by":"publisher","first-page":"3982","DOI":"10.3390\/ma13183982","article-title":"Comparison of test setups for the experimental evaluation of the primary fixation stability of acetabular cups.","volume":"13","author":"Schulze","year":"2020","journal-title":"Materials."},{"key":"B32","doi-asserted-by":"publisher","first-page":"1271","DOI":"10.1007\/s00590-015-1697-z","article-title":"Influence of cup-center-edge angle on micro-motion at the interface between the cup and host bone in cementless total hip arthroplasty: three-dimensional finite element analysis.","volume":"25","author":"Kaku","year":"2015","journal-title":"Eur J Orthop Surg Traumatol."},{"key":"B33","doi-asserted-by":"publisher","first-page":"562","DOI":"10.1016\/j.arth.2010.05.025","article-title":"The results of a press-fit-only technique for acetabular fixation in hip dysplasia.","volume":"26","author":"Takao","year":"2011","journal-title":"J Arthroplasty."},{"key":"B34","doi-asserted-by":"publisher","first-page":"1448","DOI":"10.55730\/1300-0144.5712","article-title":"The press-fit technique without screws and bone graft can be used as an alternative method in crowe type II and III hip dysplasia.","volume":"53","author":"\u00c7ataltepe","year":"2023","journal-title":"Turk J Med Sci."},{"key":"B35","doi-asserted-by":"publisher","first-page":"1595","DOI":"10.1007\/s00264-015-2951-z","article-title":"Experimental study of the installation acetabular component with uncoverage in arthroplasty patients with severe developmental hip dysplasia.","volume":"40","author":"Tikhilov","year":"2016","journal-title":"Int Orthop."},{"key":"B36","doi-asserted-by":"publisher","first-page":"1471","DOI":"10.1016\/s0021-9290(00)00096-8","article-title":"Interfacial conditions between a press-fit acetabular cup and bone during daily activities: implications for achieving bone in-growth.","volume":"33","author":"Spears","year":"2000","journal-title":"J Biomech."},{"key":"B37","doi-asserted-by":"publisher","first-page":"926","DOI":"10.1054\/arth.2002.34526","article-title":"Load transfer and fixation mode of press-fit acetabular sockets.","volume":"17","author":"Widmer","year":"2002","journal-title":"J Arthroplasty."},{"key":"B38","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1243\/09544119JEIM645","article-title":"Computational assessment of press-fit acetabular implant fixation: the effect of implant design, interference fit, bone quality, and frictional properties.","volume":"224","author":"Janssen","year":"2010","journal-title":"Proc Inst Mech Eng H."},{"key":"B39","doi-asserted-by":"publisher","first-page":"354","DOI":"10.1186\/s13018-023-03845-y","article-title":"Is the construct stability of the acetabular cup affected by the acetabular screw configuration in bone defect models?","volume":"18","author":"Nam","year":"2023","journal-title":"J Orthop Surg Res."},{"key":"B40","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1007\/s00590-014-1571-4","article-title":"Initial stability of cementless acetabular cups: press-fit and screw fixation interaction\u2013an in vitro biomechanical study.","volume":"25","author":"Tabata","year":"2015","journal-title":"Eur J Orthop Surg Traumatol."},{"key":"B41","doi-asserted-by":"publisher","first-page":"101431","DOI":"10.1016\/j.artd.2024.101431","article-title":"Preoperative three-dimensional planning using computed tomography improves screw placement in patients undergoing acetabular revision surgery.","volume":"29","author":"Brandt","year":"2024","journal-title":"Arthroplast Today."},{"key":"B42","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1016\/j.arth.2006.02.082","article-title":"Neurovascular injuries in acetabular reconstruction cage surgery: an anatomical study.","volume":"22","author":"Lavernia","year":"2007","journal-title":"J Arthroplasty."}],"container-title":["Frontiers in Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2025.1729549\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T17:54:08Z","timestamp":1766166848000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2025.1729549\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,10]]},"references-count":42,"alternative-id":["10.3389\/fmed.2025.1729549"],"URL":"https:\/\/doi.org\/10.3389\/fmed.2025.1729549","relation":{},"ISSN":["2296-858X"],"issn-type":[{"type":"electronic","value":"2296-858X"}],"subject":[],"published":{"date-parts":[[2025,12,10]]},"article-number":"1729549"}}