{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T05:08:39Z","timestamp":1780376919040,"version":"3.54.1"},"reference-count":33,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T00:00:00Z","timestamp":1780358400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Acute aortic dissection (AAD) is a life-threatening emergency requiring rapid diagnosis and treatment. Vital signs obtained at triage are immediately available and may provide useful information for early risk stratification.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate whether triage vital signs are independently associated with in-hospital mortality in patients with AAD, with a specific focus on analyzing heart rate as a categorical variable and blood pressure in clinically relevant units.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We performed a retrospective cohort study of 702 consecutive patients with AAD admitted to the emergency department of a tertiary hospital in China between January 1 and November 23, 2024. Heart rate was categorized as bradycardia (&amp;lt;60 bpm), normal (60\u2013100 bpm), or tachycardia (&amp;gt;100 bpm). Blood pressure was analyzed per 10-mmHg change. Variables significant in univariate analysis (\n                      <jats:italic>P<\/jats:italic>\n                      &amp;lt; 0.10) were entered into a multivariate model. Model performance was assessed using the area under the receiver operating characteristic curve (AUC) with 10-fold cross-validation.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 702 patients, 293 (41.7%) died during hospitalization. Multivariate logistic regression identified older age (adjusted OR 1.029 per year, 95% CI 1.017\u20131.041), male sex (adjusted OR 1.495, 95% CI 1.036\u20132.157), bradycardia (adjusted OR 2.500, 95% CI 1.300\u20134.800), tachycardia (adjusted OR 1.800, 95% CI 1.100\u20132.900), lower body temperature (adjusted OR 1.499 per 1 \u00b0C decrease, 95% CI 1.082\u20132.075), and higher diastolic blood pressure (adjusted OR 1.105 per 10-mmHg increase, 95% CI 1.001\u20131.220) as independent risk factors for in-hospital mortality. The model demonstrated acceptable discrimination (mean cross-validated AUC 0.71, 95% CI 0.68\u20130.74).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Initial triage vital signs, particularly deviations in heart rate (both low and high), lower body temperature, and higher diastolic blood pressure, are independent predictors of in-hospital mortality in patients with AAD. Assessing these readily available parameters can support early risk stratification in the emergency department.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fmed.2026.1721657","type":"journal-article","created":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T04:29:33Z","timestamp":1780374573000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Predictive value of initial triage vital signs for in-hospital mortality in acute aortic dissection patients: a retrospective study in the emergency department"],"prefix":"10.3389","volume":"13","author":[{"given":"Nan","family":"Xie","sequence":"first","affiliation":[{"name":"Emergency Department of West China Hospital, West China School of Nursing, Sichuan University","place":["Chengdu, China"]},{"name":"Disaster Medicine Center, Sichuan University","place":["Chengdu, 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