{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T05:06:47Z","timestamp":1775797607716,"version":"3.50.1"},"reference-count":20,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T00:00:00Z","timestamp":1775779200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"\n Background<\/jats:title>\n Infectious diseases education faces dual challenges: addressing knowledge sensitivity and bridging the theory-practice gap. Traditional didactic teaching inadequately cultivates both technical skills and humanistic literacy.<\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n To evaluate the tripartite efficacy of the BOPPPS model in AIDS education, focusing on knowledge acquisition, skill-attitude integration, and learning experience.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n A randomized controlled trial (RCT) enrolled 80 clinical medicine undergraduates, randomly assigned to an experimental group (BOPPPS pedagogy,\n n<\/jats:italic>\n = 40) or a control group (traditional teaching,\n n<\/jats:italic>\n = 40). Pre-class, intra-class, and post-class assessments included test scores, operational skills, and satisfaction surveys.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n The experimental group demonstrated significantly superior outcomes (\n p<\/jats:italic>\n &lt; 0.01). Cognitive dimension: immediate post-test scores (85.4 \u00b1 5.2 vs. 75.1 \u00b1 8.3;\n t<\/jats:italic>\n = 6.84) increased by 13.7%, and 1-week knowledge retention (80.1 \u00b1 6.0 vs. 63.7 \u00b1 9.5;\n t<\/jats:italic>\n = 9.12) improved by 25.8%. Skill-attitude dimension: protective operation qualification rate (92.5 vs. 67.5%; \u03c7\n 2<\/jats:sup>\n = 8.32) rose by 37.0%, and anti-discrimination attitude excellence rate (60.0 vs. 25.0%; \u03c7\n 2<\/jats:sup>\n = 10.26) increased by 140.0%. Experience dimension: overall satisfaction reached 4.63 \u00b1 0.42 (vs. 3.02 \u00b1 0.88;\n t<\/jats:italic>\n = 10.95,\n d<\/jats:italic>\n = 2.47), reflecting a 53.3% enhancement.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n The BOPPPS model, through its \u201cobjective-focused, participatory, feedback-driven\u201d mechanism, effectively integrates knowledge, skills, and humanistic competencies in infectious diseases education, providing an evidence-based paradigm for medical curriculum reform.<\/jats:p>\n <\/jats:sec>","DOI":"10.3389\/fmed.2026.1723420","type":"journal-article","created":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T04:25:32Z","timestamp":1775795132000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Practical application of the BOPPPS model in infectious diseases education: a randomized controlled trial"],"prefix":"10.3389","volume":"13","author":[{"given":"Xiaohao","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases, Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Institute for Viral Hepatitis, The Second Affiliated Hospital, Chongqing Medical University","place":["Chongqing, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shan","family":"Zhong","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Institute for Viral Hepatitis, The Second Affiliated Hospital, Chongqing Medical University","place":["Chongqing, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hu","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Institute for Viral Hepatitis, The Second Affiliated Hospital, Chongqing Medical University","place":["Chongqing, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2026,4,10]]},"reference":[{"key":"B1","first-page":"578","article-title":"Epidemic intensity in the Anthropocene","volume":"23","author":"Baker","year":"2023","journal-title":"Lancet Infect Dis"},{"key":"B2","first-page":"1461","article-title":"Translating medical evidence into education: the growing gap between knowledge production and curricular integration","volume":"385","author":"Patel","year":"2021","journal-title":"N Engl J Med."},{"key":"B3","unstructured":"Geneva\n WHO Press\n Framework for Strengthening Education on Emerging Infectious Diseases\n \n 2022"},{"key":"B4","first-page":"553","article-title":"Enhancing knowledge retention through structured lesson design: a randomized controlled trial of the BOPPPS 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