{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T15:19:02Z","timestamp":1783696742624,"version":"3.55.0"},"reference-count":48,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T00:00:00Z","timestamp":1783641600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100031514","name":"Health Commission of Chengdu Municipality","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100031514","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:p>\n                    The detrimental effects of micro- and nanoplastics (MNPs) on human health have been the subject of intense research in recent years, but there is little data on how MNPs affect intestinal health. Six participants with colonic or terminal ileal erosion were enrolled, and one erosive tissue sample plus one adjacent non-erosive tissue sample were collected from each participant. Pyrolysis gas chromatography\/mass spectrometry (Py-GC\/MS) was utilized to determine the MNP content of these tissues after pathological examination investigation verified the existence of inflammation in the erosive tissue samples. Our results revealed that MNPs were present in all intestinal samples, with a total MNP concentration of 1758.15 (664.07) mg\/kg in inflammatory tissues and 611.49 (510.64) mg\/kg in non-inflammatory intestinal tissues; the difference was statistically significant (\n                    <jats:italic>p<\/jats:italic>\n                    &amp;lt; 0.05). Three types of MNPs were identified: polyethylene (PE), polyvinyl chloride (PVC), and polystyrene (PS). PE and PVC exhibited a 100% detection rate in all tissue samples, whereas PS was found in 16.67% of samples. Correlation analysis revealed marginal associations of intestinal MNP levels with age, drinking water source and diarrhea. This work provides preliminary baseline data and hints at a weak link between MNP exposure and intestinal inflammation.\n                  <\/jats:p>","DOI":"10.3389\/fmed.2026.1732146","type":"journal-article","created":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T15:08:26Z","timestamp":1783696106000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Higher abundance of micro- and nanoplastics in inflammatory tissues from patients with intestinal erosion"],"prefix":"10.3389","volume":"13","author":[{"given":"Li-Xia","family":"Du","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, Chengdu BOE Hospital","place":["Chengdu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuan","family":"Song","sequence":"additional","affiliation":[{"name":"Center of Reproductive Medicine, Chengdu BOE Hospital","place":["Chengdu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tian-Chao","family":"Deng","sequence":"additional","affiliation":[{"name":"Department of Pathology, Chengdu BOE Hospital","place":["Chengdu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Qian","family":"Feng","sequence":"additional","affiliation":[{"name":"Department of Comprehensive Pediatric Internal Medicine, Chongqing University Three Gorges Hospital","place":["Chongqing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li-Juan","family":"Qiao","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Chengdu BOE Hospital","place":["Chengdu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Chengdu BOE Hospital","place":["Chengdu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lian-Lian","family":"Liu","sequence":"additional","affiliation":[{"name":"Center of Endoscopy, Chengdu BOE Hospital","place":["Chengdu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Xu","sequence":"additional","affiliation":[{"name":"Center of Endoscopy, Chengdu BOE Hospital","place":["Chengdu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Zeng","sequence":"additional","affiliation":[{"name":"Center of Endoscopy, Chengdu BOE Hospital","place":["Chengdu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua","family":"Qing","sequence":"additional","affiliation":[{"name":"Center of Endoscopy, Chengdu BOE Hospital","place":["Chengdu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qin","family":"Li","sequence":"additional","affiliation":[{"name":"Center of Endoscopy, Chengdu BOE Hospital","place":["Chengdu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,7,10]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"147815","DOI":"10.1016\/j.scitotenv.2021.147815","article-title":"Micro (nano) plastic pollution: the ecological influence on soil-plant system and human health.","volume":"788","author":"Allouzi","year":"2021","journal-title":"Sci Total Environ."},{"key":"B2","doi-asserted-by":"publisher","first-page":"107662","DOI":"10.1016\/j.envint.2022.107662","article-title":"Micro- and nanoplastics: a new cardiovascular risk factor?","volume":"171","author":"Zhu","year":"2023","journal-title":"Environ Int."},{"key":"B3","doi-asserted-by":"publisher","first-page":"140","DOI":"10.17756\/jfcn.2024-186","article-title":"Micro and nano plastics in the food chain: challenges, risks, and future directions.","volume":"10","author":"Mummaleti","year":"2024","journal-title":"J Food Chem Nanotechnol."},{"key":"B4","doi-asserted-by":"crossref","DOI":"10.1007\/s10311-022-01560-4","volume-title":"Higher Number of Microplastics in Tumoral Colon Tissues from Patients with Colorectal Adenocarcinoma.","author":"Cetin","year":"2023"},{"key":"B5","doi-asserted-by":"publisher","first-page":"414","DOI":"10.1021\/acs.est.1c03924","article-title":"Analysis of microplastics in human feces reveals a correlation between fecal microplastics and inflammatory bowel disease status.","volume":"56","author":"Yan","year":"2022","journal-title":"Environ Sci Technol."},{"key":"B6","doi-asserted-by":"publisher","first-page":"135227","DOI":"10.1016\/j.chemosphere.2022.135227","article-title":"Plastic particles in medicine: a systematic review of exposure and effects to human health.","volume":"303","author":"Gopinath","year":"2022","journal-title":"Chemosphere."},{"key":"B7","doi-asserted-by":"publisher","first-page":"3065","DOI":"10.1021\/acs.est.3c08902","article-title":"Micro(nano)plastics in the human body: sources, occurrences, fates, and health risks.","volume":"58","author":"Li","year":"2024","journal-title":"Environ. 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