{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T13:09:22Z","timestamp":1780664962297,"version":"3.54.1"},"reference-count":36,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T00:00:00Z","timestamp":1780617600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The COVID-19 pandemic has posed significant challenges to diagnosis, particularly when Real-time reverse transcription-polymerase chain reaction (RT-PCR) was scarce.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study evaluates the diagnostic validity of Computed tomography (CT) and its impact on patient treatment when RT-PCR was unavailable. A retrospective examination of 50 symptomatic patients from December 2022 to June 2023 was conducted. All patients underwent non-contrast chest CT scans following institutional ethical approval. CT images were analyzed by experienced radiologists, assessing CT likelihood and severity. RT-PCR tests were also conducted, and patient management decisions were recorded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The patient group had a mean age of 67.2\u202fyears (range 32\u201389\u202fyears), with 64.9% male. Ground-glass opacity (GGO) was the most common CT finding (56.8%), often peripheral, multilobar, and bilateral. Two CT phenotypes were identified. CT demonstrated high sensitivity compared to RT-PCR.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>As CT severity levels were higher in our patients, it becomes a crucial tool for early COVID-19 detection and management. Prompt CT exams, especially within 5 days of symptom onset, improve diagnostic precision. Specific CT phenotypes and severity scores provide valuable information for predicting disease severity and guiding patient management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fmed.2026.1732764","type":"journal-article","created":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T12:34:50Z","timestamp":1780662890000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Utilizing CT chest imaging for the diagnosis and monitoring of COVID infections and emergency intensive care unit strategic treatment"],"prefix":"10.3389","volume":"13","author":[{"given":"Linling","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine, The First People\u2019s Hospital of Fuyang Hangzhou","place":["Hangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongjia","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, The First People\u2019s Hospital of Fuyang Hangzhou","place":["Hangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,6,5]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1016\/j.jacr.2020.02.008","article-title":"Coronavirus (COVID-19) outbreak: what the Department of Radiology Should Know","volume":"17","author":"Kooraki","year":"2020","journal-title":"J Am Coll Radiol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"727","DOI":"10.1056\/NEJMoa2001017","article-title":"A novel coronavirus from patients with pneumonia in China, 2019","volume":"382","author":"Zhu","year":"2020","journal-title":"N Engl J Med"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1016\/S0140-6736(20)30183-5","article-title":"Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China","volume":"395","author":"Huang","year":"2020","journal-title":"Lancet"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1016\/j.ijid.2020.01.009","article-title":"The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health - the latest 2019 novel coronavirus outbreak in Wuhan, China","volume":"91","author":"Hui","year":"2020","journal-title":"Int J Infect Dis"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1016\/S0140-6736(20)30185-9","article-title":"A novel coronavirus outbreak of global health concern","volume":"395","author":"Wang","year":"2020","journal-title":"Lancet"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1007\/s11427-020-1637-5","article-title":"Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission","volume":"63","author":"Xu","year":"2020","journal-title":"Sci China Life Sci"},{"key":"ref7","first-page":"2020","volume-title":"Coronavirus Disease 2019 (COVID-19): Situation Report, 52","year":"2020"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"896","DOI":"10.1016\/S1473-3099(20)30319-4","article-title":"Estimation of COVID-19 burden in Egypt","volume":"20","author":"Hassany","year":"2020","journal-title":"Lancet Infect Dis"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1097\/RTI.0000000000000524","article-title":"Radiological Society of North America expert consensus statement on reporting chest CT findings related to COVID-19. 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