{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T19:35:37Z","timestamp":1770233737945,"version":"3.49.0"},"reference-count":28,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T00:00:00Z","timestamp":1770163200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>There is not enough radiologic data in the literature for the quantitative value of uterine stiffness and this study aims to contribute to the literature in this field.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the feasibility of measuring uterine myometrial stiffness (UMS) using 3T magnetic resonance elastography (MRE) in women with radiologically normal uteri and to explore potential associations with demographic and anatomical variables.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data on demographics, including age, BMI, obstetric history (gravida and parity), menopausal status, and oral contraceptive use, were gathered. Uterine measurements, such as the long axis, transverse diameter, anteroposterior diameter, and volume, were obtained using 3T MR imaging. UMS (in Pascals) was quantified using MRE, and its associations with various factors were assessed. Values are reported as mean \u00b1 standard deviation (SD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The study enrolled 48 women with a mean age of 37.54 \u00b1 10.47 years. The average UMS was 2714 \u00b1 300 Pa. A strong positive correlation was found between age and UMS (\n                      <jats:italic>r<\/jats:italic>\n                      = 0.814,\n                      <jats:italic>p<\/jats:italic>\n                      &amp;lt; 0.001), whereas no significant associations were found with BMI, uterine dimensions, gravida, or parity. UMS was higher in postmenopausal women than in women of reproductive age (\n                      <jats:italic>p<\/jats:italic>\n                      &amp;lt; 0.001). However, no statistically significant differences were observed between oral contraceptive users and non-users in this limited sample.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This feasibility study demonstrates the practicality of assessing uterine myometrial stiffness using 3T MRE and provides exploratory estimates in radiologically normal uteri. Larger prospective studies are required before normative ranges can be established.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fmed.2026.1743585","type":"journal-article","created":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T06:48:56Z","timestamp":1770187736000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of stiffness values of normal uterine myometrium by 3T magnetic resonance elastography"],"prefix":"10.3389","volume":"13","author":[{"given":"Levent","family":"Karaka\u015f","sequence":"first","affiliation":[{"name":"Department of Radiology, Gaziosmanpa\u015fa Training and Research Hospital","place":["\u0130stanbul, T\u00fcrkiye"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u00fcheyl","family":"Po\u00e7an","sequence":"additional","affiliation":[{"name":"Department of Radiology, \u0130stanbul Ni\u015fanta\u015f\u0131 University and BHT CLINIC \u0130stanbul Tema Hospital","place":["\u0130stanbul, T\u00fcrkiye"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u015e\u00fckr\u00fc","family":"\u015eahin","sequence":"additional","affiliation":[{"name":"Department of Radiology, Elaz\u0131\u011f Fethi Sekin City Hospital","place":["Elaz\u0131\u011f, T\u00fcrkiye"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2026,2,4]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1186\/s13244-022-01274-9","article-title":"Advances in the clinical application of ultrasound elastography in uterine imaging.","volume":"13","author":"Wang","year":"2022","journal-title":"Insights Into Imag."},{"key":"B2","doi-asserted-by":"publisher","first-page":"1923","DOI":"10.1007\/s10439-021-02769-0","article-title":"Anisotropic mechanical properties of the human uterus measured by spherical 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