{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T06:38:10Z","timestamp":1772087890619,"version":"3.50.1"},"reference-count":6,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T00:00:00Z","timestamp":1772064000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Fibrosing alopecia in a pattern distribution (FAPD) is an infrequent presentation of primary cicatricial alopecia with clinical, histopathological and trichoscopic features of Androgenetic Alopecia (AGA), as well as Lichen Planopilaris (LPP).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The aim of this study is to describe the clinical, trichoscopic and histopathological features of 46 hispanic male patients with FAPD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a retrospective study from 8 dermatological centers across four countries: Argentina, Colombia, Mexico, and Peru. Patients with clinical diagnosis of FAPD performed by 12 dermatologists experienced in trichology from 2015 to 2022 were included.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Forty-six male patients were identified, with a mean age of 39. The age of onset ranged from 20 to 63\u202fyears. 85% of the patients (\n                      <jats:italic>n<\/jats:italic>\n                      \u202f=\u202f39) had a family history of AGA. In terms of clinical characteristics, the Male Pattern of Hair Loss (MPHL) was the most common (65%). All patients showed a symmetrical distribution of the alopecia. Regarding the trichoscopic characteristics, the most frequent finding was perifollicular desquamation (96%), while most common histological finding was concentric perifollicular lamellar fibrosis (100%). FAPD was the initial clinical suspicion in only 6 patients (13%), and androgenetic alopecia was the primary initial suspicion (56.5%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The age of onset of FAPD appears to be earlier in Latin American male patients compared with European and North American male patients. Most male patients with FAPD clinically resemble AGA in their classic pattern of hair loss.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fmed.2026.1746147","type":"journal-article","created":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T05:29:36Z","timestamp":1772083776000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical, trichoscopic, and histological characteristics of 46 hispanic men with fibrosing alopecia in a pattern distribution: a retrospective multicenter analysis"],"prefix":"10.3389","volume":"13","author":[{"given":"Luis E.","family":"S\u00e1nchez-Due\u00f1as","sequence":"first","affiliation":[{"name":"Department of Dermatology, Dermatologic Institute of Jalisco \u201cDr. Jos\u00e9 Barba Rubio\u201d, University of Guadalajara","place":["Zapopan, Mexico"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irene M.","family":"Rodriguez-Escamilla","sequence":"additional","affiliation":[{"name":"Department of Dermatology, General Hospital \u201cDr. Manuel Gea Gonzalez\u201d","place":["Mexico City, Mexico"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joel A.","family":"Ram\u00edrez-S\u00e1nchez","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Dermatologic Institute of Jalisco \u201cDr. Jos\u00e9 Barba Rubio\u201d, University of Guadalajara","place":["Zapopan, Mexico"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Jimenez-Zaragoza","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Dermatologic Institute of Jalisco \u201cDr. Jos\u00e9 Barba Rubio\u201d, University of Guadalajara","place":["Zapopan, Mexico"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guillermo","family":"Solis-Ledesma","sequence":"additional","affiliation":[{"name":"Department of Dermatopathology, Dermatologic Institute of Jalisco \u201cDr. Jos\u00e9 Barba Rubio\u201d, University of Guadalajara","place":["Zapopan, Mexico"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guillermo A.","family":"Guerrero-Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Private Practitioner","place":["Monterrey, Mexico"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miguel","family":"Marti-Machado","sequence":"additional","affiliation":[{"name":"TRICOMED","place":["Buenos Aires, Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariana","family":"Lavia","sequence":"additional","affiliation":[{"name":"TRICOMED","place":["Buenos Aires, Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sonia S.","family":"Ocampo-Garza","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Autonomous University of Nuevo, University Hospital \u201cDr. Jos\u00e9 Eleuterio Gonz\u00e1lez\u201d","place":["Monterrey, Mexico"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lizet K.","family":"Rojano-Fritz","sequence":"additional","affiliation":[{"name":"Private Practitioner","place":["Barranquilla, Colombia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aldo","family":"G\u00e1lvez-Canseco","sequence":"additional","affiliation":[{"name":"Private Practitioner","place":["Lima, Peru"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leslie E.","family":"Rocha-Mendez","sequence":"additional","affiliation":[{"name":"Private Practitioner","place":["Le\u00f3n, Guanajuato, Mexico"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicole","family":"Orendain-Koch","sequence":"additional","affiliation":[{"name":"Dermika Laser Dermatologic Center","place":["Guadalajara, Mexico"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2026,2,26]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"1557","DOI":"10.1016\/j.jaad.2019.12.056","article-title":"Fibrosing alopecia in a pattern distribution","volume":"85","author":"Griggs","year":"2021","journal-title":"J Am Acad Dermatol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"2440","DOI":"10.1111\/jdv.17604","article-title":"Clinicopathological characteristics and treatment outcomes of fibrosing alopecia in a pattern distribution: a\u202fretrospective cohort study","volume":"35","author":"Jerjen","year":"2021","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1001\/archderm.136.2.205","article-title":"Fibrosing alopecia in a pattern distribution: patterned lichen planopilaris or androgenetic alopecia with a lichenoid tissue reaction pattern?","volume":"136","author":"Zinkernagel","year":"2000","journal-title":"Arch Dermatol"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1159\/000496708","article-title":"Frequency of the types of alopecia at twenty-two specialist hair clinics: a multicenter study","volume":"5","author":"Va\u00f1\u00f3-Galv\u00e1n","year":"2019","journal-title":"Skin Appendage Disord"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"e12","DOI":"10.1111\/ijd.13871","article-title":"Clinical study of fibrosing alopecia in a pattern distribution in a Latin American population","volume":"57","author":"Mardones","year":"2018","journal-title":"Int J Dermatol"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1111\/1346-8138.16155","article-title":"Distinctive age distribution and hair loss pattern putatively highlighting uniqueness of Japanese cases of fibrosing alopecia in a pattern 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