{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T16:50:11Z","timestamp":1776876611329,"version":"3.51.2"},"reference-count":46,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T00:00:00Z","timestamp":1776816000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:p>Verruciform xanthoma (VX) is a rare benign mucocutaneous proliferative lesion that primarily affects the oral mucosa and, in rare cases, the genital mucosa and skin. Due to its uncommon occurrence and varied, non-specific clinical manifestations, the condition is prone to misdiagnosis and missed diagnosis. This report introduces an even rarer case of pediatric vulvar VX, providing a detailed interpretation and analysis of the ultrasonographic features of this condition. Furthermore, in conjunction with previous literature, this report summarizes and analyzes the currently reported vulvar VX cases, aiming to obtain effective diagnostic and therapeutic information, enhance preoperative diagnostic accuracy, and improve patient prognosis.<\/jats:p>","DOI":"10.3389\/fmed.2026.1774843","type":"journal-article","created":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T16:10:20Z","timestamp":1776874220000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Giant vulvar verruciform xanthoma in a child: a rare case report and literature review"],"prefix":"10.3389","volume":"13","author":[{"given":"Yan","family":"Xia","sequence":"first","affiliation":[{"name":"Department of Ultrasonography, Hangzhou Third People's Hospital, Hangzhou Third Hospital Affiliated to Zhejiang Chinese Medical University","place":["Hangzhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Liu","sequence":"additional","affiliation":[{"name":"Cancer Center, Department of Ultrasound Medicine, Zhejiang Provincial People\u2019s Hospital (Affiliated People\u2019s Hospital), Hangzhou Medical College","place":["Zhejiang, Hangzhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongyan","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Hangzhou Third People\u2019s Hospital, Hangzhou Third Hospital Affiliated to Zhejiang Chinese Medical University","place":["Hangzhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongsheng","family":"Xia","sequence":"additional","affiliation":[{"name":"Department of Ultrasonography, Hangzhou Third People's Hospital, Hangzhou Third Hospital Affiliated to Zhejiang Chinese Medical University","place":["Hangzhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bin","family":"Dong","sequence":"additional","affiliation":[{"name":"Department of Ultrasonography, Hangzhou Third People's Hospital, Hangzhou Third Hospital Affiliated to Zhejiang Chinese Medical University","place":["Hangzhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2026,4,22]]},"reference":[{"key":"ref1","first-page":"561","volume-title":"Andrews' Diseases of the Skin: Clinical Dermatology","author":"Odom","year":"2004"},{"key":"ref2","author":"Chen","year":"2019"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1093\/ajcp\/71.2.224","article-title":"Verruciform xanthoma of the vulva. 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