{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T07:11:09Z","timestamp":1773645069133,"version":"3.50.1"},"reference-count":38,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T00:00:00Z","timestamp":1773619200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:p>Peristomal pyoderma gangrenosum (PPG) is a rare and therapeutically challenging inflammatory dermatosis predominantly affecting individuals with stoma surgery. This review provides a comprehensive overview of PPG, encompassing its etiology, clinical manifestations, diagnostic methods, treatment strategies, and nursing management. PPG\u2019s multifactorial etiology involves immune dysfunction, genetic predisposition, surgical trauma, and demographic factors, which contribute to the formation of painful ulcers that significantly impair patients\u2019 quality of life. Accurate diagnosis requires a multidisciplinary approach, including clinical evaluation, histopathological examination, and advanced diagnostic criteria. Effective management combines local wound care, systemic therapies, and surgical interventions, emphasizing a patient-centered and evidence-based approach. Nursing strategies, including advanced wound care, pain management, psychological support, nutritional interventions, and health education, play a vital role in optimizing outcomes and preventing recurrence. Future research should focus on the development of specific biomarkers, novel therapeutic agents, and standardized nursing protocols to address the unmet needs in PPG care. This integrated diagnostic, therapeutic, and nursing framework aims to enhance patient outcomes and provide insights for future clinical and research advancements.<\/jats:p>","DOI":"10.3389\/fmed.2026.1774931","type":"journal-article","created":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T06:39:29Z","timestamp":1773643169000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Peristomal pyoderma gangrenosum: a review of nursing research progress"],"prefix":"10.3389","volume":"13","author":[{"given":"Guowei","family":"Chen","sequence":"first","affiliation":[{"name":"Department of General Surgery, Chongqing General Hospital","place":["Chongqing, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoxu","family":"Lan","sequence":"additional","affiliation":[{"name":"Department of Hemodialysis, Chongqing General Hospital","place":["Chongqing, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fang","family":"Li","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Chongqing General Hospital","place":["Chongqing, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deyuan","family":"Zeng","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Chongqing General Hospital","place":["Chongqing, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luhong","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Chongqing General Hospital","place":["Chongqing, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoyu","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Nursing, Xipeng Town Health Center","place":["Chongqing, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Chongqing General Hospital","place":["Chongqing, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2026,3,16]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"769","DOI":"10.1001\/archsurg.1994.01420310101019","article-title":"Peristomal pyoderma gangrenosum and inflammatory bowel disease","volume":"129","author":"Cairns","year":"1994","journal-title":"Arch Surg"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"938","DOI":"10.1007\/BF02052602","article-title":"Parastomal pyoderma gangrenosum in inflammatory bowel disease","volume":"37","author":"Tjandra","year":"1994","journal-title":"Dis Colon Rectum"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1093\/gastro\/got013","article-title":"Diagnosis and management of parastomal pyoderma gangrenosum","volume":"1","author":"Wu","year":"2013","journal-title":"Gastroenterol Rep"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1067\/mjd.2000.104515","article-title":"Parastomal pyoderma gangrenosum: clinical features and management","volume":"6","author":"Lyon","year":"2000","journal-title":"J Am Acad Dermatol"},{"key":"ref5","first-page":"377","article-title":"Analysis of 20 cases of peristomal pyoderma gangrenosum","volume":"6","author":"Cao","year":"2000","journal-title":"Foreign Med Sci Surg Sect"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"e22405","DOI":"10.7759\/cureus.22405","article-title":"Diagnosis and treatment difficulty in early-onset peristomal pyoderma gangrenosum associated with ulcerative colitis: a case report","volume":"14","author":"Imaizumi","year":"2022","journal-title":"Cureus"},{"key":"ref7","first-page":"525","article-title":"Peristomal pyoderma gangrenosum after colectomy for Crohn disease. 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