{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T07:03:16Z","timestamp":1780470196297,"version":"3.54.1"},"reference-count":33,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T00:00:00Z","timestamp":1780444800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This retrospective study evaluated the impact of a family collaboration care model on disease perception, self-management, and quality of life among elderly patients with multidrug-resistant pulmonary tuberculosis (MDR-TB).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective study was conducted on elderly patients diagnosed with MDR-TB at Henan Provincial Chest Hospital between January 2022 and December 2024. Based on nursing records, patients were classified into a standard care group and a family collaboration care group. Disease perception, self-management ability, and quality of life were assessed using the BIPQ, AHSMSRS, and WHOQOL-BREF, respectively. The partial eta-squared, Cohen\u2019s d, and Hedges\u2019 g were used to evaluate effect size.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 57 elderly patients (45 males, 12 females) were included, with 30 in the standard care group and 27 in the family collaboration care group. Compared with the standard care group, the family collaboration care group had significantly lower total disease perception scores (33.44\u202f\u00b1\u202f4.82 vs. 40.97\u202f\u00b1\u202f7.10,\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&amp;lt;\u202f0.001), higher self-management scores (131.85\u202f\u00b1\u202f13.97 vs. 108.13\u202f\u00b1\u202f11.29,\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&amp;lt;\u202f0.001), and higher quality-of-life scores (\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&amp;lt;\u202f0.001 for all domains). Effect sizes were large for disease perception (Hedges\u2019 g\u202f=\u202f\u22121.211), self-management ability (Hedges\u2019 g\u202f=\u202f1.856), and quality of life (Hedges\u2019 g\u202f=\u202f2.496).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Family collaboration care may be associated with better disease perception, improved self-management ability, and enhanced quality of life among elderly patients with MDR-TB. This model may serve as a practical approach for optimizing nursing management in MDR-TB care, although its effectiveness warrants further validation in future studies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fmed.2026.1781223","type":"journal-article","created":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T06:08:22Z","timestamp":1780466902000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Effects of a family collaboration care model on disease perception, self-management, and quality of life in elderly patients with multidrug-resistant pulmonary tuberculosis: a retrospective study"],"prefix":"10.3389","volume":"13","author":[{"given":"Zhaojie","family":"Wang","sequence":"first","affiliation":[{"name":"Henan Provincial Chest Hospital, Zhengzhou University","place":["Zhengzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Pang","sequence":"additional","affiliation":[{"name":"Henan Provincial Chest Hospital, Zhengzhou University","place":["Zhengzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,6,3]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"23","DOI":"10.3390\/s23156781","article-title":"Weak localization of radiographic manifestations in pulmonary tuberculosis from chest X-ray: a systematic review","volume":"23","author":"Feyisa","year":"2023","journal-title":"Sensors (Basel)"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1016\/j.jgar.2024.05.018","article-title":"Prevalence and patterns of drug-resistant Mycobacterium tuberculosis in newly diagnosed patients in China: a systematic review and meta-analysis","volume":"38","author":"Jin","year":"2024","journal-title":"J Glob Antimicrob Resist"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"1086","DOI":"10.1186\/s12879-025-11491-4","article-title":"Treatment outcomes and associated influencing factors among elderly patients with rifampicin-resistant tuberculosis: a multicenter, retrospective, cohort study in China","volume":"25","author":"Liu","year":"2025","journal-title":"BMC Infect Dis"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"100398","DOI":"10.1016\/j.jctube.2023.100398","article-title":"Survival status and risk factors for mortality among multidrug-resistant tuberculosis patients in Addis Ababa, Ethiopia: a retrospective follow-up study","volume":"33","author":"Getahun","year":"2023","journal-title":"J Clin Tuberc Other Mycobact Dis"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"3087","DOI":"10.2147\/idr.S524300","article-title":"Epidemiology and molecular drug-resistance patterns of tuberculosis in non-elderly patients in Luoyang, China, 2019-2023","volume":"18","author":"Wang","year":"2025","journal-title":"Infect Drug Resist"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"2534656","DOI":"10.1080\/22221751.2025.2534656","article-title":"Mixed infections and heteroresistance of Mycobacterium tuberculosis among multidrug-resistant tuberculosis in China: a genomic epidemiology study","volume":"14","author":"Liu","year":"2025","journal-title":"Emerg Microbes Infect"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"2055102919844504","DOI":"10.1177\/2055102919844504","article-title":"Illness perception and high readmission health outcomes","volume":"6","author":"Sawyer","year":"2019","journal-title":"Health Psychol Open"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"4056548","DOI":"10.1155\/2023\/4056548","article-title":"Factors associated with medication adherence in elderly individuals with tuberculosis: a qualitative study","volume":"2023","author":"Hassani","year":"2023","journal-title":"Can J Infect Dis Med Microbiol"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"940","DOI":"10.1186\/s12889-024-18476-z","article-title":"A serial mediating effect of perceived family support on psychological well-being","volume":"24","author":"An","year":"2024","journal-title":"BMC Public Health"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"2570212","DOI":"10.1080\/10641963.2025.2570212","article-title":"Interdisciplinary collaborative care model combined with family empowerment in patients with comorbid hypertension and diabetes: a study on blood pressure\/glucose control and psychosocial adaptation based on the COM-B model","volume":"47","author":"Wu","year":"2025","journal-title":"Clin Exp Hypertens"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"651","DOI":"10.1001\/jama.2020.11747","article-title":"Effect of a collaborative care model on depressive symptoms and glycated hemoglobin, blood pressure, and serum cholesterol among patients with depression and diabetes in India: the INDEPENDENT randomized clinical trial","volume":"324","author":"Ali","year":"2020","journal-title":"JAMA"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1186\/s12889-020-10055-2","article-title":"Tuberculosis-related stigma and its determinants in Dalian, Northeast China: a cross-sectional study","volume":"21","author":"Chen","year":"2021","journal-title":"BMC Public Health"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"4191","DOI":"10.12998\/wjcc.v12.i20.4191","article-title":"Clinical effects of detailed nursing management interventions on medication adherence and disease perception in patients with drug-resistant tuberculosis","volume":"12","author":"Chen","year":"2024","journal-title":"World J Clin Cases"},{"key":"ref14","first-page":"7","article-title":"Guidelines for the diagnosis and treatment of pulmonary tuberculosis","volume":"20","author":"CM","year":"2013","journal-title":"Chinese Practical Rural Doctor Journal"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"15265","DOI":"10.1038\/s41598-025-00415-6","article-title":"Latent profile analysis of fear of progression in Chinese hematologic malignancy survivors","volume":"15","author":"Liu","year":"2025","journal-title":"Sci Rep"},{"key":"ref16","first-page":"93","article-title":"Research progress on health self-management assessment tools for adults","volume":"25","author":"Huang","year":"2010","journal-title":"Nurs J"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"e74056","DOI":"10.2196\/74056","article-title":"Health self-management behaviors as a bridge between electronic health literacy and health-related quality of life: cross-sectional study from China","volume":"27","author":"Zhang","year":"2025","journal-title":"J Med Internet Res"},{"key":"ref18","first-page":"1127","article-title":"Introduction and usage instructions for the Chinese version of the World Health Organization quality of life questionnaire","volume":"1","author":"Hao","year":"2000","journal-title":"Modern Rehabilitation"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1186\/s12955-019-1130-0","article-title":"Measurement equivalence of the English, Chinese and Malay versions of the World Health Organization quality of life (WHOQOL-BREF) questionnaires","volume":"17","author":"Cheung","year":"2019","journal-title":"Health Qual Life Outcomes"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1111\/jocn.13775","article-title":"The role of the family in supporting the self-management of chronic conditions: a qualitative systematic review","volume":"27","author":"Whitehead","year":"2018","journal-title":"J Clin Nurs"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"460","DOI":"10.3390\/healthcare11040460","article-title":"The effect of a nurse-led family involvement program on anxiety and depression in patients with advanced-stage hepatocellular carcinoma","volume":"11","author":"Klankaew","year":"2023","journal-title":"Healthcare (Basel)"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1186\/s40748-025-00203-0","article-title":"Improving maternal well-being: a matrescence education pilot study for new mothers","volume":"11","author":"Trinko","year":"2025","journal-title":"Matern Health Neonatol Perinatol"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"11150","DOI":"10.1038\/s41598-025-96260-8","article-title":"Treatment adherence and its association with family support among pulmonary tuberculosis patients in Jinja, eastern Uganda","volume":"15","author":"Alinaitwe","year":"2025","journal-title":"Sci Rep"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1186\/s12879-020-05354-3","article-title":"The effects of family, society and national policy support on treatment adherence among newly diagnosed tuberculosis patients: a cross-sectional study","volume":"20","author":"Chen","year":"2020","journal-title":"BMC Infect Dis"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"e12629","DOI":"10.1111\/jjns.12629","article-title":"The role of family support in medication adherence and quality of life among tuberculosis patients: a scoping review","volume":"22","author":"Lutfian","year":"2025","journal-title":"Jpn J Nurs Sci"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"S202","DOI":"10.1016\/j.ijtb.2022.10.022","article-title":"Drug resistant tuberculosis among elderly: challenges","volume":"69","author":"Chopra","year":"2022","journal-title":"Indian J Tuberc"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"2381468320915239","DOI":"10.1177\/2381468320915239","article-title":"Measuring stigma to assess the social justice implications of health-related policy decisions: application to novel treatment regimens for multidrug-resistant tuberculosis","volume":"5","author":"Dowdy","year":"2020","journal-title":"MDM Policy Pract"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"725045","DOI":"10.3389\/fpsyt.2021.725045","article-title":"The biobehavioral family model: An evidence-based approach to biopsychosocial research, residency training, and patient care","volume":"12","author":"Wood","year":"2021","journal-title":"Front Psych"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"21","DOI":"10.3390\/ijerph21091135","article-title":"Integrated approach to chronic pain-the role of psychosocial factors and multidisciplinary treatment: a narrative review","volume":"21","author":"Kova\u010devi\u0107","year":"2024","journal-title":"Int J Environ Res Public Health"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"208","DOI":"10.1016\/j.ijtb.2017.08.031","article-title":"Cost effectiveness of decentralised care model for managing MDR-TB in India","volume":"65","author":"John","year":"2018","journal-title":"Indian J Tuberc"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"43","DOI":"10.21010\/Ajidv19i2.5","article-title":"Family support, motivation, and patient adherence to tuberculosis treatment: insights from Indonesia","volume":"19","author":"Dana","year":"2025","journal-title":"Afr J Infect Dis"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1186\/s12890-023-02440-5","article-title":"Effectiveness of family support health education intervention to improve health-related quality of life among pulmonary tuberculosis patients in Melaka, Malaysia","volume":"23","author":"Saidi","year":"2023","journal-title":"BMC Pulm Med"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"3387","DOI":"10.2147\/ppa.S558068","article-title":"Latent profile analysis and influencing factors of medication-related burden in multidrug-resistant tuberculosis patients in Chengdu, China","volume":"19","author":"Li","year":"2025","journal-title":"Patient Prefer Adherence"}],"container-title":["Frontiers in Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2026.1781223\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T06:08:24Z","timestamp":1780466904000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2026.1781223\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,3]]},"references-count":33,"alternative-id":["10.3389\/fmed.2026.1781223"],"URL":"https:\/\/doi.org\/10.3389\/fmed.2026.1781223","relation":{},"ISSN":["2296-858X"],"issn-type":[{"value":"2296-858X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,3]]},"article-number":"1781223"}}