{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T06:17:16Z","timestamp":1771481836072,"version":"3.50.1"},"reference-count":22,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T00:00:00Z","timestamp":1771459200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:p>\n                    This study compared the effects of two postoperative steroid administration routes\u2014oral prednisone versus local intraoperative dexamethasone gel foam\u2014on hearing outcomes and complications following primary stapedectomy for otosclerosis. In this retrospective comparative study, 76 consecutive patients who underwent primary stapedectomy by a single senior surgeon at a tertiary center between 2016 and 2024 were included. Patients received either oral prednisone (50\u202fmg daily for 5\u202fdays postoperatively;\n                    <jats:italic>n<\/jats:italic>\n                    \u202f=\u202f37) or local dexamethasone (8\u202fmg applied intraoperatively on gel foam;\n                    <jats:italic>n<\/jats:italic>\n                    \u202f=\u202f39). Pre- and postoperative audiometric data, demographic characteristics, and postoperative complications were analyzed. Audiometry was performed 6\u201312\u202fweeks after surgery, assessing air-conduction (AC), bone-conduction (BC), and air-bone gap (ABG) thresholds. Both groups demonstrated significant postoperative AC improvement and comparable ABG closure, with no significant differences in overall AC gain or ABG reduction. BC thresh-olds improved in both groups; however, greater BC gain was observed in the oral steroid group. Postoperative tinnitus and infections occurred more frequently in the local steroid group, while vertigo rates were similar between groups. In conclusion, oral and local steroid administration following primary stapedectomy were associated with comparable improvements in air-conduction and air\u2013bone gap outcomes. Although greater bone-conduction recovery and fewer postoperative complications were observed in the oral steroid group, these findings should be interpreted cautiously given the retrospective design and limited sample size.\n                  <\/jats:p>","DOI":"10.3389\/fmed.2026.1782153","type":"journal-article","created":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T05:24:19Z","timestamp":1771478659000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Audiometric changes following oral versus local gel foam steroid administration after stapedectomy in otosclerosis patients: a retrospective comparative study"],"prefix":"10.3389","volume":"13","author":[{"given":"Alaa","family":"Safia","sequence":"first","affiliation":[{"name":"Department of Otolaryngology, Otology Unit, Ziv Medical Center","place":["Safed, Israel"]},{"name":"Department of Speech, Language, and Audiology, Ziv Medical Center","place":["Safed, Israel"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raed","family":"Farhat","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Otology Unit, Ziv Medical Center","place":["Safed, Israel"]},{"name":"Department of Speech, Language, and Audiology, Ziv Medical Center","place":["Safed, Israel"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Uday","family":"Abd Elhadi","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Otology Unit, Ziv Medical Center","place":["Safed, Israel"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samraa","family":"Zahwa","sequence":"additional","affiliation":[{"name":"Department of Speech, Language, and Audiology, Ziv Medical Center","place":["Safed, Israel"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Doris","family":"Jubran","sequence":"additional","affiliation":[{"name":"Department of Speech, Language, and Audiology, Ziv Medical Center","place":["Safed, Israel"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saleh","family":"Amara","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Otology Unit, Ziv Medical Center","place":["Safed, Israel"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shlomo","family":"Merchavy","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Otology Unit, Ziv Medical Center","place":["Safed, Israel"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saqr","family":"Massoud","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Otology Unit, Ziv Medical Center","place":["Safed, Israel"]},{"name":"Department of Speech, Language, and Audiology, Ziv Medical Center","place":["Safed, 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effects of glucocorticoids on ischemia\u2013reperfusion injury of outer hair cells","volume":"116","author":"Tabuchi","year":"2006","journal-title":"Laryngoscope"}],"container-title":["Frontiers in 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