{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T07:11:26Z","timestamp":1773645086912,"version":"3.50.1"},"reference-count":24,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T00:00:00Z","timestamp":1773619200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:p>Although sarcoidosis is a granulomatous disease with unknown etiology involving multisystems, the pleura is rarely affected in this disease. Here, a case of sarcoidosis with pleural nodules and pleural effusion was presented. The patient suffered from dry cough and dyspnea lasting for 4 weeks. Chest computed tomography showed pulmonary nodules, subpleural nodules, mediastinal lymphadenopathy and bilateral pleural effusion. Thoracoscopic pleural biopsy was performed, and histopathological examination demonstrated non-caseating granulomas, confirming sarcoidosis-related pleural involvement. The patient was treated with corticosteroids, and all discomfort symptoms gradually regressed. A follow-up CT performed 8 weeks later exhibited the complete resolution of pleural effusion. The present case report highlights that when pleural effusion and pleural nodule are observed in a patient, sarcoidosis should be considered as the underlying disease while other potential causes are ruled out.<\/jats:p>","DOI":"10.3389\/fmed.2026.1786968","type":"journal-article","created":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T06:39:47Z","timestamp":1773643187000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Pulmonary sarcoidosis with pleural involvement in a 44-year-old patient: a case report"],"prefix":"10.3389","volume":"13","author":[{"given":"Bin","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine, Binzhou Medical University Hospital","place":["Binzhou Shandong, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nailiang","family":"Zhai","sequence":"additional","affiliation":[{"name":"Department of Respiratory 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