{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T07:02:41Z","timestamp":1779692561931,"version":"3.53.1"},"reference-count":20,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T00:00:00Z","timestamp":1779667200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005047","name":"Liaoning Provincial Natural Science Foundation","doi-asserted-by":"crossref","award":["2025-BS-0661"],"award-info":[{"award-number":["2025-BS-0661"]}],"id":[{"id":"10.13039\/501100005047","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Inclusion body myositis (IBM) is a rare inflammatory myopathy characterized by progressive limb muscle weakness, dysphagia, and respiratory impairment. In this report, we review the case of a pregnant patient with IBM who underwent cesarean section safely under general anesthesia. Perioperative anesthetic management for these patients has been rarely described.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>We describe a 43-year-old parturient (G2P1) who was diagnosed with IBM 7\u202fyears prior to this pregnancy, with confirmed involvement of the flexor digitorum profundus and quadriceps muscles. She had mild dysphagia but no respiratory muscle involvement. Due to gestational diabetes mellitus and fetal macrosomia, she required a cesarean section. General anesthesia was administered with aspiration precautions and prophylaxis against malignant hyperthermia (MH). General anesthesia, combined with a reduced dose of rocuronium and reversal with sugammadex, facilitated uneventful extubation within 30\u202fmin postoperatively. The newborn was assigned a 10\/10 Apgar score at 1 and 5\u202fmin after delivery, and the patient was discharged on postoperative day 4 without complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This case demonstrates that, with precautionary preparations targeting potential complications\u2014including aspiration risk, MH, exaggerated sensitivity to neuromuscular blocking agents (NMBAs), and postoperative pulmonary complications\u2014general anesthesia may be a safe and feasible option for cesarean delivery in IBM patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fmed.2026.1799325","type":"journal-article","created":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T06:04:26Z","timestamp":1779689066000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Cesarean delivery in a patient with inclusion body myositis: is general anesthesia safe? A case report"],"prefix":"10.3389","volume":"13","author":[{"given":"Yanan","family":"Pu","sequence":"first","affiliation":[{"name":"Department of Anesthesiology, The Second Affiliated Hospital of Dalian Medical University","place":["Dalian, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Su","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, The Second Affiliated Hospital of Dalian Medical University","place":["Dalian, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liya","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, The Second Affiliated Hospital of Dalian Medical University","place":["Dalian, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, The Second Affiliated Hospital of Dalian Medical University","place":["Dalian, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiayuan","family":"Niu","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, The Second Affiliated Hospital of Dalian Medical University","place":["Dalian, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, The Second Affiliated Hospital of Dalian Medical University","place":["Dalian, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,5,25]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"426","DOI":"10.1212\/WNL.0000000000000642","article-title":"Evaluation and construction of diagnostic criteria for inclusion body 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