{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T16:32:04Z","timestamp":1790785924403,"version":"4.1.0"},"reference-count":25,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T00:00:00Z","timestamp":1779235200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>\n                      Diabetic neuropathy is a prevalent and debilitating complication of poorly controlled diabetes mellitus, primarily affecting peripheral nerves. Patients commonly present with symptoms such as burning sensation, numbness, tingling, and pain in the extremities, often associated with sensory deficits. Current conventional management provides limited symptomatic relief, highlighting the need for complementary approaches. In Ayurveda, this condition can be considered an\n                      <jats:italic>Upadrava<\/jats:italic>\n                      (complication) of\n                      <jats:italic>Prameha<\/jats:italic>\n                      (diabetes mellitus) and is managed through a combination of internal medications, external therapies, and detoxification procedures.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methodology<\/jats:title>\n                    <jats:p>A 65-year-old male patient with a 15-year history of uncontrolled diabetes mellitus presented with a severe burning sensation in both lower limbs. The patient was managed with Ayurvedic interventions, including internal medications for 1\u202fmonth followed by 21\u202fdays of inpatient Panchakarma therapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Clinical assessment using the visual analog scale (VAS), Neuropathy Disability Score (NDS), and neuropathy grading showed significant improvement following the intervention. The patient, who initially presented with moderate neuropathy, showed marked clinical improvement after 2\u202fmonths of treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This case suggests that Ayurvedic interventions may offer a beneficial complementary approach in the management of diabetic peripheral neuropathy. Further systematic studies are required to substantiate these findings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fmed.2026.1802855","type":"journal-article","created":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T04:39:22Z","timestamp":1779251962000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Ayurvedic management of diabetic peripheral neuropathy: a case report"],"prefix":"10.3389","volume":"13","author":[{"given":"Arathy","family":"Menon","sequence":"first","affiliation":[{"name":"Department of Kayachikitsa, Shree Swaminarayan Ayurvedic College, Swaminarayan University","place":["Gandhinagar, Gujarat, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Chacko","sequence":"additional","affiliation":[{"name":"Department of Kayachikitsa, Rajiv Gandhi Ayurveda Medical College","place":["Mahe, Puducherry, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Delvin T.","family":"Robin","sequence":"additional","affiliation":[{"name":"Department of Swasthavritta, Amrita School of Ayurveda, Amrita Vishwa Vidyapeetham","place":["Kollam, Kerala, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Preethi","family":"Mohan","sequence":"additional","affiliation":[{"name":"Department of Agada Tantra and Vyavahara Ayurveda, Amrita School of Ayurveda, Amrita Vishwa Vidyapeetham","place":["Kollam, Kerala, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,5,20]]},"reference":[{"key":"ref1","first-page":"88","article-title":"Prevalence and associated determinants of diabetic peripheral neuropathy in individuals with type 2 diabetes mellitus in rural South India","volume":"44","author":"Darivemula","year":"2019","journal-title":"Indian J Community Med"},{"key":"ref2","volume-title":"Charaka 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Kashaya Kalpana","author":"Krishnan","year":"2016"},{"key":"ref25","volume-title":"Sharangadhara Samhita","author":"Sharangadhara","year":"1984"}],"container-title":["Frontiers in Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2026.1802855\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T04:39:47Z","timestamp":1779251987000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2026.1802855\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,20]]},"references-count":25,"alternative-id":["10.3389\/fmed.2026.1802855"],"URL":"https:\/\/doi.org\/10.3389\/fmed.2026.1802855","relation":{},"ISSN":["2296-858X"],"issn-type":[{"value":"2296-858X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,20]]},"article-number":"1802855"}}