{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T12:07:01Z","timestamp":1784117221358,"version":"3.55.0"},"reference-count":47,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T00:00:00Z","timestamp":1784073600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:p>Abrikossoff entities, also known as granular cell tumors (GCTs), are categorized as rare benign soft-tissue tumors of Schwann cell origin. The most common site of predilection is the oral cavity, followed by the skin, breast, digestive tract, and tracheobronchial tree; the least common location is the central nervous system. They are benign growths associated with a good prognosis, with surgical resection being their standard treatment. However, sometimes, they become malignant. They typically manifest as solitary tumors; hence, multiple lesions are rare. Here, we report a 49-year-old woman with a palpable and painful mass in her right breast. While the clinical and radiological features favored a diagnosis of epidermoid cyst, immunohistochemistry confirmed an Abrikossoff tumor. No recurrence of the GCT was assessed during the control.<\/jats:p>","DOI":"10.3389\/fmed.2026.1810784","type":"journal-article","created":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T11:10:20Z","timestamp":1784113820000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Granular cell tumor mimicking breast carcinoma in a 49-year-old female: a case report"],"prefix":"10.3389","volume":"13","author":[{"given":"Fadoua","family":"El Mansouri","sequence":"first","affiliation":[{"name":"Immunopathology-Immunotherapy-Immunomonitoring Laboratory, Faculty of Medicine, Mohammed VI University of Sciences and Health (UM6SS)","place":["Casablanca, Morocco"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khadija","family":"Bichri","sequence":"additional","affiliation":[{"name":"Immunopathology-Immunotherapy-Immunomonitoring Laboratory, Faculty of Medicine, Mohammed VI University of Sciences and Health (UM6SS)","place":["Casablanca, Morocco"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zakaria","family":"Hafiani","sequence":"additional","affiliation":[{"name":"Immunopathology-Immunotherapy-Immunomonitoring Laboratory, Faculty of Medicine, Mohammed VI University of Sciences and Health (UM6SS)","place":["Casablanca, Morocco"]},{"name":"Moulay Youssef Breast Center","place":["Casablanca, Morocco"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed","family":"Zarqaoui","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Les Iris Clinic","place":["Casablanca, Morocco"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bouchra","family":"Ghazi","sequence":"additional","affiliation":[{"name":"Immunopathology-Immunotherapy-Immunomonitoring Laboratory, Faculty of Medicine, Mohammed VI University of Sciences and Health (UM6SS)","place":["Casablanca, Morocco"]},{"name":"Reproductive Health Physiopathology Laboratory, Mohammed IV Center for Research and Innovation (CM6RI)","place":["Rabat, Morocco"]},{"name":"Department of Obstetrics and Gynecology, Mohammed VI International University Hospital","place":["Bouskoura, Morocco"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,7,15]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1149735","DOI":"10.3389\/fmed.2023.1149735","article-title":"Case report: Abrikossoff's tumor of the facial skin","volume":"10","author":"Ardeleanu","year":"2023","journal-title":"Front Med"},{"key":"B2","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1007\/BF02078314","volume":"260","author":"Abrikossoff","year":"1926","journal-title":"Virchows Arch path Anat"},{"key":"B3","unstructured":"Granular Cell Tumor\n          \n          \n            \n              Neelon\n              D\n            \n            \n              Lannan\n              F\n    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         \n          \n          2019"},{"key":"B47","doi-asserted-by":"publisher","first-page":"26","DOI":"10.4103\/2349-6029.184008","article-title":"Granular cell tumor: An uncommon tumor of Schwann cell origin","volume":"3","author":"Tiwary","year":"2016","journal-title":"Indian J Dermatopathol Diagn Dermatol"}],"container-title":["Frontiers in 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