{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T12:03:38Z","timestamp":1785413018395,"version":"3.56.0"},"reference-count":18,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T00:00:00Z","timestamp":1785369600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:p>Background<\/jats:p>\n                  <jats:p>Esophageal duplication cysts (EDCs) are rare congenital foregut malformations, accounting for only 0.5 to 2.5% of all esophageal masses. Although typically diagnosed during childhood, adult presentations are uncommon and frequently characterized by asymptomatic progression or non-specific clinical features. We report the case of a 58-year-old male presenting with atypical chest pain and anxiety. Multimodal imaging (CT and MRI) revealed a massive posterior mediastinal mass measuring 12\u202f\u00d7\u202f11 cm that exerted significant mechanical compression on the left atrium. The patient underwent a successful right posterolateral thoracotomy for surgical resection. Histopathological examination confirmed the diagnosis of an esophageal duplication cyst. The postoperative course was uneventful, with complete resolution of symptoms. Giant EDCs should be considered in the differential diagnosis of mediastinal masses in adults, even when presenting with atypical cardiovascular symptoms. Surgical resection remains the definitive treatment of choice to prevent long-term complications and establish a formal histological diagnosis.<\/jats:p>","DOI":"10.3389\/fmed.2026.1811057","type":"journal-article","created":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T11:10:24Z","timestamp":1785409824000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Case Report: Giant esophageal duplication cyst mimicking cardiac compression in an adult"],"prefix":"10.3389","volume":"13","author":[{"given":"Eduardo","family":"Agustin-Godinez","sequence":"first","affiliation":[{"name":"Laboratorio de Patologia e Inmunohistoquimica Especializada DIME, Hospital Medica Campestre","place":["Leon, Guanajuato, Mexico"]},{"name":"Division de Ciencias de la Salud, Universidad de Guanajuato","place":["Leon, Guanajuato, Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis de Jesus","family":"Prieto-Utrera","sequence":"additional","affiliation":[{"name":"Laboratorio de Patologia e Inmunohistoquimica Especializada DIME, Hospital Medica Campestre","place":["Leon, Guanajuato, Mexico"]},{"name":"Division de Ciencias de la Salud, Universidad de Guanajuato","place":["Leon, Guanajuato, Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cesar Augusto","family":"Guisao-Valencia","sequence":"additional","affiliation":[{"name":"Laboratorio de Patologia e Inmunohistoquimica Especializada DIME, Hospital Medica Campestre","place":["Leon, Guanajuato, Mexico"]},{"name":"Division de Ciencias de la Salud, Universidad de Guanajuato","place":["Leon, Guanajuato, Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruben","family":"Tachiquin-Gutierrez","sequence":"additional","affiliation":[{"name":"Hospital Angeles Leon","place":["Leon, Guanajuato, Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Serrano-Arellano","sequence":"additional","affiliation":[{"name":"Hospital San Jose","place":["Celaya, Guanajuato, Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diego","family":"Ontiveros-Ramirez","sequence":"additional","affiliation":[{"name":"Division de Ciencias de la Salud, Universidad de Guanajuato","place":["Leon, Guanajuato, Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco Tulio","family":"Dominguez-Castellanos","sequence":"additional","affiliation":[{"name":"Division de Ciencias de la Salud, Universidad de Guanajuato","place":["Leon, Guanajuato, Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Murguia-Perez","sequence":"additional","affiliation":[{"name":"Laboratorio de Patologia e Inmunohistoquimica Especializada DIME, Hospital Medica Campestre","place":["Leon, Guanajuato, Mexico"]},{"name":"Division de Ciencias de la Salud, Universidad de Guanajuato","place":["Leon, Guanajuato, Mexico"]},{"name":"UMAE Hospital de Especialidades N\u00b0 1, Centro Medico Nacional Bajio","place":["Leon, Guanajuato, Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,7,30]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.21037\/med-22-38","article-title":"Esophageal duplication cysts: a clinical practice review","volume":"7","author":"Wahi","year":"2023","journal-title":"Mediastinum"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"149","DOI":"10.4103\/2249-4847.101452","article-title":"Mediastinal enteric cyst in a neonate","volume":"1","author":"Singhal","year":"2012","journal-title":"J Clin Neonatol"},{"key":"ref3","first-page":"329","article-title":"Esophageal duplication cyst. 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