{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T04:55:43Z","timestamp":1781585743395,"version":"3.54.5"},"reference-count":30,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T00:00:00Z","timestamp":1781568000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:p>Morning glory syndrome (MGS) is a congenital abnormal optic disc eye disease. In 1970, Kindler first described it and reported the disease in detail. Its fundus performance resembled a blooming morning glory, so it was named. This disease is relatively rare, and it was first reported in 1985 in China.<\/jats:p>","DOI":"10.3389\/fmed.2026.1819842","type":"journal-article","created":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T04:30:03Z","timestamp":1781584203000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Morning glory syndrome with retinal detachment and literature review\u2014a case report"],"prefix":"10.3389","volume":"13","author":[{"given":"Yanhong","family":"Ding","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Gongshu District Wenhui Community Health Service Center (Gongshu District Hospital of Traditional Chinese Medicine)","place":["Hangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ai","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Wenzhou TCM Hospital of Zhejiang Chinese Medical University","place":["Wenzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,6,16]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1016\/0002-9394(70)92269-5","article-title":"Morning glory syndrome: unusual congenital optic disk anomaly","volume":"69","author":"Kindler","year":"1970","journal-title":"Am J Ophthalmol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"1509","DOI":"10.3390\/jcm13051509","article-title":"Congenital optic disc anomalies: insights from multimodal imaging","volume":"13","author":"Cennamo","year":"2024","journal-title":"J Clin Med"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"626","DOI":"10.1111\/aos.12778","article-title":"Morning glory syndrome disc anomaly in childhood-a population-based study","volume":"93","author":"Ceynowa","year":"2015","journal-title":"Acta Ophthalmol"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"e78550","DOI":"10.7759\/cureus.78550","article-title":"Vitrectomy combined with gas tamponade for the treatment of morning glory syndrome with Rhegmatogenous retinal detachment: a case report","volume":"17","author":"Xin","year":"2025","journal-title":"Cureus."},{"key":"ref5","doi-asserted-by":"publisher","first-page":"684","DOI":"10.1136\/bjo.73.8.684","article-title":"Morning glory syndrome associated with marked persistent hyperplastic primary vitreous and lens colobornas","volume":"73","author":"Cennamo","year":"1989","journal-title":"Br J Ophthalmol"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"342","DOI":"10.1016\/s0161-6420(89)32886-7","article-title":"The spectrum of cavitary optic disc anomalies in a family","volume":"96","author":"Slusher","year":"1989","journal-title":"Ophthalmology"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"1565","DOI":"10.1086\/375555","article-title":"Mutations of the PAX6 gene detected in patients with a variety of optic-nerve malformations","volume":"72","author":"Azuma","year":"2003","journal-title":"Am J Hum Genet"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1136\/bjo.74.1.56","article-title":"Morning glory syndrome: a histopathological study","volume":"74","author":"Manschot","year":"1990","journal-title":"Br J Ophthalmol"},{"key":"ref9","first-page":"705","article-title":"A case of morning glory syndrome associated with contractile movement of the optic disc and subretinal neovascularization","volume":"100","author":"Chuman","year":"1996","journal-title":"Nippon Ganka Gakkai Zasshi"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1097\/ICU.0000000000000425","article-title":"Congenital anomalies of the optic disc: insights from optical coherence tomography imaging","volume":"28","author":"Jeng-Miller","year":"2017","journal-title":"Curr Opin Ophthalmol"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1016\/j.jfo.2020.05.015","article-title":"Morning glory syndrome and ultrasound study","volume":"44","author":"Gin\u00e9s-Gallego","year":"2021","journal-title":"J Fr Ophtalmol"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"631","DOI":"10.13464\/j.scuxbyxb.2017.04.027","article-title":"The clinical value of ultrasound manifestations and characteristics of rare infantile morning glory syndrome","volume":"48","author":"Juxian","year":"2017","journal-title":"J Sichuan Univ"},{"key":"ref13","volume-title":"StatPearls","author":"Ruia","year":"2023"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"674","DOI":"10.3928\/23258160-20180831-04","article-title":"Peripheral retinal nonperfusion in pediatric patients with morning glory syndrome","volume":"49","author":"She","year":"2018","journal-title":"Ophthalmic Surg Lasers Imaging Retina"},{"key":"ref15","first-page":"774","article-title":"CT diagnosis of morning glory syndrome","volume":"34","author":"Kong","year":"2000","journal-title":"Chinese J Radiol"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"2010","DOI":"10.3174\/ajnr.A3542","article-title":"Morning glory disc anomaly: characteristic MR imaging findings","volume":"34","author":"Ellika","year":"2013","journal-title":"AJNR Am J Neuroradiol"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"600","DOI":"10.3760\/cma.j.issn.1005-1015.2011.06.030","article-title":"A case of chrysanthemum syndrome","volume":"27","author":"Xiaoyan","year":"2011","journal-title":"Chinese J Ocular Fundus Dis"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1159\/000510958","article-title":"Case report: Fibroglial retinal tissue in contractile morning glory disc anomaly","volume":"12","author":"Ramirez-Estudillo","year":"2021","journal-title":"Case Rep Ophthalmol."},{"key":"ref19","doi-asserted-by":"publisher","first-page":"145","DOI":"10.3760\/cma.j.issn.1674-845X.2012.03.005","article-title":"Analysis of clinical characteristics of morning glory syndrome in infants and young children","volume":"14","author":"Xu","year":"2012","journal-title":"J Optometry Ophthalmol"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"206","DOI":"10.3760\/cma.j.issn.1005-1015.2013.02.023","article-title":"Vitrectomy for pediatric morning glory syndrome with macular hole and proliferative retinal detachment","volume":"29","author":"Yuhua","year":"2013","journal-title":"Chinese J Ocular Fundus Dis"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"290","DOI":"10.3928\/0191-3913-20050901-11","article-title":"Morning glory syndrome: clinical, computerized tomographic, and ultrasonographic findings","volume":"42","author":"Harasymowycz","year":"2005","journal-title":"J Pediatr Ophthalmol Strabismus"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1007\/s10384-006-0310-8","article-title":"Clinical feature analysis of congenital optic nerve abnormalities","volume":"50","author":"Kim","year":"2006","journal-title":"Jpn J Ophthalmol"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"1262","DOI":"10.1136\/bjophthalmol-2013-303565","article-title":"Clinical characteristics and treatment of 22 eyes of morning glory syndrome associated with persistent hyperplastic primary vitreous","volume":"97","author":"Fei","year":"2013","journal-title":"Br J Ophthalmol"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"89","DOI":"10.3980\/j.issn.2222-3959.2010.01.21","article-title":"Vitrectomy of rhegmatogenous retinal detachment in morning glory syndrome","volume":"3","author":"Yang","year":"2010","journal-title":"Int J Ophthalmol"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"7","DOI":"10.3969\/J.ISSN.1005-328X.2017.04.003","article-title":"Clinical experience in the diagnosis and treatment of comprehensive amblyopia training for 23 children with morning glory syndrome","volume":"25","author":"Dongqing","year":"2017","journal-title":"Chinese J Strabismus Pediatric Ophthalmol"},{"key":"ref26","first-page":"157","article-title":"Clinical analysis of 2769 cases of congenital nasolacrimal duct obstruction","volume":"20","author":"Chen","year":"2012","journal-title":"Chinese J Strabismus Pediatric Ophthalmol"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1159\/000516205","article-title":"Management of retinal detachment associated with morning glory disc syndrome","volume":"12","author":"Etheridge","year":"2021","journal-title":"Case Rep Ophthalmol"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"766","DOI":"10.18240\/ijo.2022.05.12","article-title":"Prophylactic juxtapapillary laser photocoagulation in pediatric morning glory syndrome","volume":"15","author":"Zou","year":"2022","journal-title":"Int J Ophthalmol"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"e57817","DOI":"10.7759\/cureus.57817","article-title":"Morning glory anomaly with serous macular detachment","volume":"16","author":"Goli","year":"2024","journal-title":"Cureus"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"415","DOI":"10.3928\/23258160-20240409-01","article-title":"Rapid resolution of serous retinal detachment in morning glory disc anomaly with Oral acetazolamide treatment","volume":"55","author":"Lee","year":"2024","journal-title":"Ophthalmic Surg Lasers Imaging Retina"}],"container-title":["Frontiers in Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2026.1819842\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T04:30:10Z","timestamp":1781584210000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2026.1819842\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,16]]},"references-count":30,"alternative-id":["10.3389\/fmed.2026.1819842"],"URL":"https:\/\/doi.org\/10.3389\/fmed.2026.1819842","relation":{},"ISSN":["2296-858X"],"issn-type":[{"value":"2296-858X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,16]]},"article-number":"1819842"}}