{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T15:57:44Z","timestamp":1792684664313,"version":"4.5.0"},"reference-count":7,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T00:00:00Z","timestamp":1780963200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:p>This report describes a 59-year-old woman with a history of malignancy and post-tuberculosis lung disease complicated by chronic cavitary pulmonary aspergillosis. She was admitted with worsening hemoptysis and underwent bronchial artery embolization. However, she subsequently developed massive post-procedural hemoptysis, requiring mechanical ventilation. Sputum metagenomic next-generation sequencing detected SARS-CoV-2 and bacterial pathogens, prompting Paxlovid treatment for COVID-19 pneumonia. While her respiratory symptoms improved, epigastric pain developed. Based on elevated serum amylase\/lipase and CT-confirmed peripancreatic inflammation, she was diagnosed with acute pancreatitis. One year later, pulmonary tuberculosis and liver metastasis recurred. This case highlights acute pancreatitis temporally associated with COVID-19 pneumonia in a patient with multiple competing risk factors. Further, this case underscores the diagnostic complexity of structural lung disease with overlapping infections such as COVID-19 and stresses on the need for long-term surveillance.<\/jats:p>","DOI":"10.3389\/fmed.2026.1828229","type":"journal-article","created":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T05:41:46Z","timestamp":1780983706000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Acute pancreatitis temporally associated with COVID-19 pneumonia in a patient with post-tuberculosis chronic pulmonary aspergillosis: a case report"],"prefix":"10.3389","volume":"13","author":[{"given":"Wenqing","family":"Yu","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases, Taizhou School of Clinical Medicine, The Affiliated Taizhou People\u2019s Hospital of Nanjing Medical University, Nanjing Medical University, Taizhou","place":["Jiangsu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peiqing","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Taizhou School of Clinical Medicine, The Affiliated Taizhou People\u2019s Hospital of Nanjing Medical University, Nanjing Medical University, Taizhou","place":["Jiangsu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingdong","family":"Ding","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Taizhou School of Clinical Medicine, The Affiliated Taizhou People\u2019s Hospital of Nanjing Medical University, Nanjing Medical University, Taizhou","place":["Jiangsu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Taizhou School of Clinical Medicine, The Affiliated Taizhou People\u2019s Hospital of Nanjing Medical University, Nanjing Medical University, Taizhou","place":["Jiangsu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Taizhou School of Clinical Medicine, The Affiliated Taizhou People\u2019s Hospital of Nanjing Medical University, Nanjing Medical University, Taizhou","place":["Jiangsu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daming","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Taizhou School of Clinical Medicine, The Affiliated Taizhou People\u2019s Hospital of Nanjing Medical University, Nanjing Medical University, Taizhou","place":["Jiangsu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengjing","family":"Gu","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Taizhou School of Clinical Medicine, The Affiliated Taizhou People\u2019s Hospital of Nanjing Medical University, Nanjing Medical University, Taizhou","place":["Jiangsu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,6,9]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1038\/s42255-021-00347-1","article-title":"SARS-CoV-2 infects and replicates in cells of the human endocrine and exocrine pancreas.","volume":"3","author":"M\u00fcller","year":"2021","journal-title":"Nat Metab."},{"key":"B2","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1038\/s41392-024-01796-2","article-title":"Infection with SARS-CoV-2 can cause pancreatic impairment.","volume":"9","author":"Deng","year":"2024","journal-title":"Signal Transduct Target Ther."},{"key":"B3","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1038\/s41581-020-00357-4","article-title":"Immunity, endothelial injury and complement-induced coagulopathy in 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