{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T05:59:55Z","timestamp":1780898395667,"version":"3.54.1"},"reference-count":26,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T00:00:00Z","timestamp":1780876800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Primary open-angle glaucoma (POAG) is a progressive optic neuropathy; elevated intraocular pressure (IOP) is the only broadly modifiable risk factor. Some elderly patients remain uncontrolled on multi-drug regimens and are not immediate candidates for laser or filtering surgery. This CARE-compliant case report describes an integrative approach in such a patient.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>This case describes a 76-year-old woman with drug-refractory POAG and fluctuating IOP despite quadruple topical therapy. Adjunct electroacupuncture (EA, twice weekly) was initiated on March 28, 2025. IOP decreased from 12\u202fmmHg in the right eye (OD) \/ 29\u202fmmHg in the left eye (OS) to within target after the first two sessions and remained stable; best-corrected visual acuity (BCVA) improved from 0.4 (OD) \/ 0.25 (OS) to 0.5 in both eyes (OU). No major adverse events were observed. The observed clinical course was consistent with previously reported short-term IOP-lowering and ocular-perfusion effects of acupuncture in POAG.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>EA layered on top of standard care may be a feasible adjunct for short-term IOP stabilization and symptomatic improvement in drug-refractory POAG. However, given that topical antiglaucoma therapy was continued throughout the intervention and the inherent limitations of a single-case design, causal attribution cannot be established, and confirmation in randomized sham-controlled trials with longer follow-up is needed.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fmed.2026.1835330","type":"journal-article","created":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T05:36:30Z","timestamp":1780896990000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Electroacupuncture as an adjunctive therapy for drug-refractory primary open-angle glaucoma: a CARE-compliant case report"],"prefix":"10.3389","volume":"13","author":[{"given":"Yiqing","family":"Zhang","sequence":"first","affiliation":[{"name":"The Third Clinical Medical College, Zhejiang Chinese Medical University","place":["Zhejiang, 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University","place":["Zhejiang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaofeng","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Acupuncture and Moxibustion, The Third Affiliated Hospital of Zhejiang Chinese Medical University","place":["Zhejiang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhong","family":"Di","sequence":"additional","affiliation":[{"name":"Department of Acupuncture and Moxibustion, The Third Affiliated Hospital of Zhejiang Chinese Medical University","place":["Zhejiang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,6,8]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"1788","DOI":"10.1016\/s0140-6736(23)01289-8","article-title":"Glaucoma: now and 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