{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T23:36:08Z","timestamp":1792798568327,"version":"4.5.0"},"reference-count":63,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T00:00:00Z","timestamp":1782345600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aimed to evaluate the predictive value of critical care echocardiographic parameters for weaning outcomes in patients receiving venoarterial extracorporeal membrane oxygenation (VA-ECMO) for cardiogenic shock.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A comprehensive literature search was conducted across PubMed, Embase, Cochrane Library, Web of Science, Scopus, and CINAHL from inception to December 2025. Studies reporting echocardiographic predictors of VA-ECMO weaning outcomes were included. A two-component analytical approach was applied, which pooled standardized mean differences for association analyses and used bivariate random-effects modeling (Reitsma method) for diagnostic accuracy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 37 studies encompassing 3,458 patients were analyzed. Aortic valve opening status exhibited the highest discriminative ability (AUC\u202f=\u202f0.88, 95% CI: 0.82\u20130.93), followed by left ventricular outflow tract velocity-time integral (AUC\u202f=\u202f0.85, 95% CI: 0.81\u20130.88), tissue Doppler-derived mitral annular systolic velocity (AUC\u202f=\u202f0.81, 95% CI: 0.76\u20130.86), and left ventricular ejection fraction (AUC\u202f=\u202f0.79, 95% CI: 0.75\u20130.83). Provisional reference thresholds, derived primarily from studies using a 48-h decannulation definition, included LVEF 20\u201325%, LVOT-VTI\u202f\u2265\u202f10\u202fcm, and TAPSE \u226517\u202fmm; these should be interpreted as exploratory rather than confirmatory.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This meta-analysis describes a hierarchy of echocardiographic parameters for predicting VA-ECMO weaning success and provides provisional reference thresholds that may inform\u2014but do not replace \u2014 individualized clinical judgment in cardiogenic shock management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fmed.2026.1835564","type":"journal-article","created":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T05:31:18Z","timestamp":1782365478000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Meta-analysis of the predictive value of critical care echocardiography for weaning outcomes in patients with VA-ECMO-assisted cardiogenic shock"],"prefix":"10.3389","volume":"13","author":[{"given":"Miao","family":"Niu","sequence":"first","affiliation":[{"name":"Beijing Jingmei Group General Hospital","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongshun","family":"Feng","sequence":"additional","affiliation":[{"name":"Beijing Jingmei Group General Hospital","place":["Beijing, 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