{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T04:49:15Z","timestamp":1782103755143,"version":"3.54.5"},"reference-count":24,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T00:00:00Z","timestamp":1782086400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To evaluate the effectiveness of a clinical decision support system in improving management of the entire blood transfusion process using a retrospective before-and-after comparative study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A closed-loop transfusion decision support system was developed and implemented hospital-wide in 2020 following a 1-month pilot. Outcomes before implementation (Jan 2018\u2013Jun 2020) and after implementation (Jul 2020\u2013Dec 2022) were compared, including documentation quality and completeness, documentation time, nursing satisfaction, and transfusion adverse events.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      After implementation, completeness of transfusion records increased from 97.1% to 99.1% (\n                      <jats:italic>P<\/jats:italic>\n                      &amp;lt; 0.05). Documentation time significantly decreased and nursing satisfaction significantly improved (both\n                      <jats:italic>P<\/jats:italic>\n                      &amp;lt; 0.001). A statistically significant difference was observed in the reported incidence of transfusion adverse reactions between the pre- and post-implementation periods (\u03c7\n                      <jats:sup>2<\/jats:sup>\n                      = 9.41,\n                      <jats:italic>P<\/jats:italic>\n                      &amp;lt; 0.05; OR = 1.39, 95% CI: 1.13\u20131.73).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The system standardizes transfusion management, improves documentation completeness, reduces nursing workload, and enhances management of transfusion reactions.<\/jats:p>\n                  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