{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T06:03:01Z","timestamp":1781071381446,"version":"3.54.1"},"reference-count":59,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T00:00:00Z","timestamp":1781049600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>eHealth interventions represent a novel approach to improving Post Intensive Care Syndrome-Family. However, the effectiveness of these interventions on psychological outcomes in the families of ICU patients remains uncertain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The purpose of this study was to examine the effectiveness of eHealth interventions in alleviating psychological symptoms (anxiety, depression, and post-traumatic stress disorder) of Post Intensive Care Syndrome-Family.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We systematically searched the databases across Cochrane Library, PubMed, Web of Science, Embase, and CINAHL from 1st January 2012 to 27th June 2025. Randomized controlled trials of eHealth interventions aimed at improving Post Intensive Care Syndrome-Family were included in the review.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>This systematic review included 11 randomized controlled trials, involving 1,200 participants. The pooled results demonstrated that eHealth interventions did not significantly alleviate anxiety, depression, or PTSD symptoms in family members of ICU patients within 3\u202fmonths of follow-up. However, subgroup analyses indicated that eHealth with early-stage psychological support led to a statistically significant improvement in depression symptoms (SMD\u202f=\u202f\u22120.32, 95% CI: \u22120.62 to \u22120.01).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>eHealth interventions did not demonstrate statistically significant short-term (\u22643-month follow-up) improvements in psychological symptoms of Post Intensive Care Syndrome-Family. Integrating early-stage psychological support into eHealth interventions may have a potential benefit in improving the psychological symptoms of ICU patients\u2019 families, although further rigorous validation is needed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Systematic review registration<\/jats:title>\n                    <jats:p>\n                      <jats:ext-link>https:\/\/www.crd.york.ac.uk\/PROSPERO\/view\/CRD420250656227<\/jats:ext-link>\n                      , Identifier: CRD420250656227.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fmed.2026.1847415","type":"journal-article","created":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T05:41:09Z","timestamp":1781070069000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Effects of eHealth interventions on psychological outcomes of post intensive care syndrome-family: a systematic review and meta-analysis"],"prefix":"10.3389","volume":"13","author":[{"given":"Baolin","family":"Huang","sequence":"first","affiliation":[{"name":"School of Public Health and Nursing, Hangzhou Normal University","place":["Hangzhou, Zhejiang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaqi","family":"Li","sequence":"additional","affiliation":[{"name":"School of Public Health and Nursing, Hangzhou Normal University","place":["Hangzhou, Zhejiang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaibo","family":"Shen","sequence":"additional","affiliation":[{"name":"School of Public Health and Nursing, Hangzhou Normal University","place":["Hangzhou, Zhejiang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheng","family":"He","sequence":"additional","affiliation":[{"name":"School of Public Health and Nursing, Hangzhou Normal University","place":["Hangzhou, Zhejiang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruoyu","family":"Luo","sequence":"additional","affiliation":[{"name":"School of Nursing, Zhejiang Chinese Medical University","place":["Hangzhou, Zhejiang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yangyang","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Public Health and Nursing, Hangzhou Normal University","place":["Hangzhou, Zhejiang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na","family":"Yin","sequence":"additional","affiliation":[{"name":"School of Public Health and Nursing, Hangzhou Normal University","place":["Hangzhou, Zhejiang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiyong","family":"Jing","sequence":"additional","affiliation":[{"name":"Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College","place":["Hangzhou, Zhejiang, 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