{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T04:55:30Z","timestamp":1781758530941,"version":"3.54.5"},"reference-count":20,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T00:00:00Z","timestamp":1781740800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:p>\n                    <jats:italic>Leclercia adecarboxylata<\/jats:italic>\n                    is a motile, Gram-negative bacillus in the Enterobacteriaceae family and is ubiquitous in nature. In our study, we report a case of catheter-associated bloodstream infection caused by multidrug-resistant\n                    <jats:italic>L. adecarboxylata<\/jats:italic>\n                    in a colon tumor patient. The clinical symptom of the patient was high fever with chills. Initially, the patient was treated empirically with cefoperazone-sulbactam. Although cefoperazone-sulbactam was used for 4\u202fdays, the patient still had a fever. Then the bacterial cultures of the peripheral blood and catheter were positive for\n                    <jats:italic>L. adecarboxylata<\/jats:italic>\n                    . The treatment regimen was changed to meropenem. After the treatment, the patient\u2019s clinical symptoms improved and the patient was discharged. Although\n                    <jats:italic>L. adecarboxylata<\/jats:italic>\n                    is regarded as a highly sensitive pathogen, it was a multidrug-resistant bacterium in our study. We recommend that the treatment of\n                    <jats:italic>L. adecarboxylata<\/jats:italic>\n                    should be based on antimicrobial sensitivity tests.\n                  <\/jats:p>","DOI":"10.3389\/fmed.2026.1861083","type":"journal-article","created":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T04:34:08Z","timestamp":1781757248000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Case Report: Catheter-associated multidrug-resistant Leclercia adecarboxylata bloodstream infection in a colon tumor patient"],"prefix":"10.3389","volume":"13","author":[{"given":"Ning","family":"Du","sequence":"first","affiliation":[{"name":"Department of Pharmacy, National Cancer Center\/National Clinical Research Center for Cancer \/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College","place":["Shenzhen, Guangdong, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"You","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, The First Hospital of Qiqihar","place":["Qiqihar, Heilongjiang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhe","family":"Chen","sequence":"additional","affiliation":[{"name":"Qiqihar Medical University","place":["Qiqihar, Heilongjiang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,6,18]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1556\/030.65.2018.009","article-title":"A rarely isolated Gram-negative bacterium in microbiology laboratories: Leclercia adecarboxylata \u2020","volume":"65","author":"\u00c7i\u00e7ek","year":"2018","journal-title":"Acta Microbiol Immunol 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Microbiol"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"7844377","DOI":"10.1155\/crdi\/7844377","article-title":"A unique case report of Leclercia adecarboxylata causing Monomicrobial neurosurgical infections","volume":"2025","author":"Purcell","year":"2025","journal-title":"Case Rep Infect Dis"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2020\/7403152","article-title":"Catheter-related ESBL-producing Leclercia adecarboxylata septicemia in hemodialysis patient: an emerging pathogen?","volume":"2020","author":"Alosaimi","year":"2020","journal-title":"Case Rep Infect Dis"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"724","DOI":"10.1111\/j.1469-0691.2004.00892.x","article-title":"Natural antimicrobial susceptibility patterns and biochemical profiles of Leclercia adecarboxylata strains","volume":"10","author":"Stock","year":"2004","journal-title":"Clin Microbiol Infect"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"1620","DOI":"10.1099\/jmm.0.059535-0","article-title":"Leclercia adecarboxylata and catheter-related bacteraemia: review of the literature and outcome with regard to catheters and patients","volume":"62","author":"De Mauri","year":"2013","journal-title":"J Med Microbiol"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"3129","DOI":"10.1128\/JCM.00948-12","article-title":"Catheter-related bacteremia caused by multidrug-resistant Leclercia adecarboxylata in a patient with breast cancer","volume":"50","author":"Shin","year":"2012","journal-title":"J Clin Microbiol"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"e2023052","DOI":"10.4084\/MJHID.2023.052","article-title":"A rare case of multidrug-resistant Leclercia adecarboxylata catheter-related bloodstream infection and an updated brief literature review","volume":"15","author":"Colangelo","year":"2023","journal-title":"Mediterr J Hematol Infect 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