{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T05:18:11Z","timestamp":1787894291669,"version":"build-2784847793"},"reference-count":47,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T00:00:00Z","timestamp":1787875200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000030","name":"Centers for Disease Control and Prevention","doi-asserted-by":"publisher","award":["U48DP006392"],"award-info":[{"award-number":["U48DP006392"]}],"id":[{"id":"10.13039\/100000030","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"\n Introduction<\/jats:title>\n Expanding access to culturally relevant physical activity (PA) programs is key to supporting healthy brain aging among older Latinos. The C.E.R.E.B.R.O. study compared two Spanish-language PA programs delivered remotely to Latinos with subjective cognitive impairment. BAILAMOS\u2122 was a 6-month Latin dance-based intervention, and \u00a1En Forma y Fuerte! (Fit &amp; Strong!) was a 3-month multicomponent program.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n This pilot randomized trial took place remotely via Zoom. Participants were healthy, inactive, and Spanish speaking (aged 60-82). Participants were randomized via computer-generated block randomization to either BAILAMOS\u2122 or \u00a1En Forma y Fuerte!. The objective of the trial was to compare feasibility of both remote interventions. Feasibility was assessed via (1) reach, (2) recruitment rate, (3) adherence to intervention, (4) retention, and (5) adverse events. Acceptability was assessed quantitatively and qualitatively via a post-program evaluation survey of program components.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n The C.E.R.E.B.R.O. study reached 401 individuals, screened 199 individuals, and enrolled &amp; randomized 38 participants (mean age = 68.89 \u00b1 9.74 years; 75% female). The recruitment rate was 9.48%. Nineteen participants were randomized to BAILAMOS\u2122 and nineteen to \u00a1En Forma y Fuerte!. Mean attendance for BAILAMOS\u2122 was 55.51% across 48 sessions, while mean attendance for \u00a1En Forma y Fuerte! was 68.42% across 24 sessions, falling under our pre-determined benchmarks. Retention rates were 84.21% for BAILAMOS\u2122 and 89.47% for \u00a1En Forma y Fuerte!, meeting our success criteria. Program evaluations highlighted high satisfaction, with higher instructor ratings within \u00a1En Forma y Fuerte!. No serious adverse events were reported.<\/jats:p>\n <\/jats:sec>\n \n Discussion<\/jats:title>\n Both remotely delivered, culturally tailored PA programs demonstrated strong retention, high participant satisfaction, and acceptable safety among older Latino adults with subjective cognitive impairment. Although recruitment and adherence remained challenging, higher attendance in the shorter-duration program suggests intervention length may influence sustained engagement. These findings support the potential of remote PA programs to increase access among older Latino adults and highlight the need for improved recruitment and engagement strategies in future trials.<\/jats:p>\n <\/jats:sec>\n \n Clinical Trial Registration<\/jats:title>\n \n https:\/\/clinicaltrials.gov\/study\/NCT05588778?term=NCT05588778&amp;rank=1<\/jats:ext-link>\n , identifier [NCT05588778].\n <\/jats:p>\n <\/jats:sec>","DOI":"10.3389\/fmed.2026.1862017","type":"journal-article","created":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T04:31:35Z","timestamp":1787891495000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Feasibility and acceptability of two remote physical activity programs for older Latino adults: the C.E.R.E.B.R.O. study, a pilot randomized trial"],"prefix":"10.3389","volume":"13","author":[{"given":"Jocelyn","family":"Ocampo-Mota","sequence":"first","affiliation":[{"name":"Department of Kinesiology and Nutrition, University of Illinois Chicago","place":["Chicago, IL, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuliana","family":"Soto","sequence":"additional","affiliation":[{"name":"Department of Kinesiology and Nutrition, University of Illinois Chicago","place":["Chicago, IL, United States"]},{"name":"Department of Medicine, University of Illinois Chicago","place":["Chicago, IL, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel A.","family":"Negrete","sequence":"additional","affiliation":[{"name":"Department of Kinesiology and Nutrition, University of Illinois Chicago","place":["Chicago, IL, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo","family":"Cardiel","sequence":"additional","affiliation":[{"name":"Department of Kinesiology and Nutrition, University of Illinois Chicago","place":["Chicago, IL, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brynne Karlinsey","family":"Skidmore","sequence":"additional","affiliation":[{"name":"Department of Kinesiology and Nutrition, University of Illinois Chicago","place":["Chicago, IL, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana","family":"Pinto","sequence":"additional","affiliation":[{"name":"Department of Kinesiology and Nutrition, University of Illinois Chicago","place":["Chicago, IL, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David X.","family":"Marquez","sequence":"additional","affiliation":[{"name":"Department of Kinesiology and Nutrition, University of Illinois Chicago","place":["Chicago, IL, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,8,28]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/j.jalz.2018.06.3063","article-title":"Racial and ethnic estimates of Alzheimer\u2019s disease and related dementias in the United States (2015-2060) in adults aged =65 years.","volume":"15","author":"Matthews","year":"2019","journal-title":"Alzheimers Dement."},{"key":"B2","doi-asserted-by":"publisher","first-page":"277","DOI":"10.14283\/jpad.2021.27","article-title":"Association of subjective cognitive decline with risk of cognitive impairment and dementia: a systematic review and meta-analysis of prospective longitudinal studies.","volume":"8","author":"Wang","year":"2021","journal-title":"J Prev Alzheimers Dis."},{"key":"B3","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1016\/j.jalz.2014.01.001","article-title":"A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer\u2019s disease.","volume":"10","author":"Jessen","year":"2014","journal-title":"Alzheimers Dement."},{"key":"B4","doi-asserted-by":"publisher","first-page":"7715","DOI":"10.1002\/alz.14232","article-title":"Subjective cognitive decline and cognitive change among diverse middle-aged and older Hispanic\/Latino adults: results from the Study of Latinos-Investigation of Neurocognitive Aging (SOL-INCA).","volume":"20","author":"M\u00e1rquez","year":"2024","journal-title":"Alzheimers Dement."},{"key":"B5","doi-asserted-by":"publisher","first-page":"1677","DOI":"10.1002\/alz.12589","article-title":"Addressing the disparities in dementia risk, early detection and care in Latino populations: highlights from the second Latinos &. 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