{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T05:17:56Z","timestamp":1787807876775,"version":"build-2784847793"},"reference-count":15,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T00:00:00Z","timestamp":1787788800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Veno-venous extracorporeal membrane oxygenation (VV-ECMO) is a life-saving salvage therapy for treating severe respiratory failure. We present a case of trauma-related hypoxemia with severe tricuspid chordae tendinae rupture managed with VV-ECMO.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>\n                      We report the successful use of VV-ECMO in a 29-year-old patient with severe acute respiratory distress syndrome (ARDS). Refractory hypoxemia persisted despite maximal conventional therapy during the course of treatment at the outside hospital. Under VV-ECMO support, the patient\u2019s oxygen saturation improved, allowing for the down-titration of ventilator parameters. However, when an attempt was made to reduce the ECMO settings, the patient\u2019s oxygen saturation decreased. Transesophageal echocardiography (TEE) revealed a traumatic rupture of the tricuspid chordae tendineae, which was identified as the underlying etiology of the patient\u2019s severe ARDS. Following surgical repair and subsequent improvement in oxygenation, the patient was successfully decannulated from VV-ECMO. Post-decannulation, the patient developed a high fever, later confirmed as\n                      <jats:italic>Burkholderia cepacia<\/jats:italic>\n                      infective endocarditis, which responded well to targeted antimicrobial therapy.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>VV-ECMO should be considered a viable supportive therapy for patients with trauma-induced ARDS. However, if acute hypoxemia persists despite conventional interventions during VV-ECMO support, immediate differential diagnosis is warranted. Notably, bedside echocardiography serves as a critical tool for identifying underlying cardiac etiologies of refractory hypoxemia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fmed.2026.1877495","type":"journal-article","created":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T04:26:18Z","timestamp":1787804778000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Focusing on persistent hypoxemia during VV-ECMO secondary to traumatic tricuspid valve injury: a case report"],"prefix":"10.3389","volume":"13","author":[{"given":"Yunpeng","family":"Zhao","sequence":"first","affiliation":[{"name":"Department of Critical Care Medicine, Affiliated Jinhua Hospital Zhejiang University School of Medicine","place":["Jinhua, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, Affiliated Jinhua Hospital Zhejiang University School of Medicine","place":["Jinhua, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, Affiliated Jinhua Hospital Zhejiang University School of Medicine","place":["Jinhua, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,8,27]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"CD010381","DOI":"10.1002\/14651858.CD010381.pub3","article-title":"Extracorporeal membrane oxygenation for critically ill adults.","volume":"9","author":"Burrell","year":"2023","journal-title":"Cochrane Database Syst Rev"},{"key":"B2","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1016\/S2213-2600(18)30452-1","article-title":"Venovenous extracorporeal membrane oxygenation for acute respiratory distress syndrome: a systematic review and 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VA-ECMO as a bridge to successful reoperative cardiac surgery in a case of traumatic tricuspid valve injury.","volume":"2023","author":"Jacob","year":"2023","journal-title":"J Surg Case Rep"}],"container-title":["Frontiers in Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2026.1877495\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T04:26:19Z","timestamp":1787804779000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2026.1877495\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,27]]},"references-count":15,"alternative-id":["10.3389\/fmed.2026.1877495"],"URL":"https:\/\/doi.org\/10.3389\/fmed.2026.1877495","relation":{},"ISSN":["2296-858X"],"issn-type":[{"value":"2296-858X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,27]]},"article-number":"1877495"}}