{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T05:18:42Z","timestamp":1787635122655,"version":"build-2736575974"},"reference-count":36,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T00:00:00Z","timestamp":1787616000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Granulomatous prostatitis (GP) is a relatively uncommon disorder, accounting for approximately 0. 8% to 1.0% of all benign inflammatory prostatic conditions. Xanthogranulomatous prostatitis (XGP) is an exceptionally rare subtype of GP, with only a limited number of cases documented in the medical literature. Clinically and radiologically, this entity often mimics prostatic carcinoma, necessitating histopathological examination for an accurate diagnosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>\n                      A 69-year-old man presented with a multi-year history of urinary frequency, nocturia, dysuria, and dull flank pain. Clinical evaluation and laboratory studies revealed an elevated prostate-specific antigen (PSA) level. Ultrasonography demonstrated prostatic enlargement with heterogeneous echogenicity and a 1.7-cm intravesical protrusion. Prostate magnetic resonance imaging (MRI) indicated a prostatic volume of 46.33 cm\n                      <jats:sup>3<\/jats:sup>\n                      . A lesion measuring up to 2.4 cm in maximum diameter was localized to the right basal transitional zone and right basal fibromuscular stroma. The lesion exhibited low signal intensity on T2-weighted imaging, hyperintensity on diffusion-weighted imaging (DWI), and restricted diffusion with a correspondingly low signal on the apparent diffusion coefficient (ADC) map. Bladder involvement was also noted, yielding a Prostate Imaging Reporting and Data System (PI-RADS) score of 4. The patient subsequently underwent transurethral resection of the prostate (TURP) as a therapeutic intervention. Histopathological examination of the resected tissue confirmed the diagnosis of XGP.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>XGP is an extremely rare prostatic pathology, and histopathological examination remains the gold standard for definitive diagnosis. Conservative management and TURP constitute the recommended therapeutic approaches for this condition.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fmed.2026.1883799","type":"journal-article","created":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T04:23:20Z","timestamp":1787631800000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Xanthogranulomatous prostatitis mimicking prostate carcinoma: a case report and comprehensive literature review"],"prefix":"10.3389","volume":"13","author":[{"given":"Mingfeng","family":"Ji","sequence":"first","affiliation":[{"name":"Department of Urology, Second Affiliated Hospital of Dalian Medical University","place":["Dalian, Liaoning, China"]},{"name":"Liaoning Provincial Key Laboratory of Urological Digital Precision Diagnosis and Treatment","place":["Dalian, Liaoning, China"]},{"name":"Liaoning Engineering Research Center of Integrated Precision Diagnosis and 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